Search Results - "LIPPENS, S."

Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality by Remijsen, Q, Kuijpers, T W, Wirawan, E, Lippens, S, Vandenabeele, P, Vanden Berghe, T

“…Neutrophil extracellular traps (NETs) are chromatin structures loaded with antimicrobial molecules. They can trap and kill various bacterial, fungal and…”
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Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria by Wirawan, E, Vande Walle, L, Kersse, K, Cornelis, S, Claerhout, S, Vanoverberghe, I, Roelandt, R, De Rycke, R, Verspurten, J, Declercq, W, Agostinis, P, Vanden Berghe, T, Lippens, S, Vandenabeele, P

“…Autophagy and apoptosis are two important and interconnected stress-response mechanisms. However, the molecular interplay between these two pathways is not…”
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Developing 3D SEM in a broad biological context by KREMER, A., LIPPENS, S., BARTUNKOVA, S., ASSELBERGH, B., BLANPAIN, C., FENDRYCH, M., GOOSSENS, A., HOLT, M., JANSSENS, S., KROLS, M., LARSIMONT, J.‐C., Mc GUIRE, C., NOWACK, M.K., SAELENS, X., SCHERTEL, A., SCHEPENS, B., SLEZAK, M., TIMMERMAN, V., THEUNIS, C., VAN BREMPT, R., VISSER, Y., GUÉRIN, C.J.

“…Summary When electron microscopy (EM) was introduced in the 1930s it gave scientists their first look into the nanoworld of cells. Over the last 80 years EM…”
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Proteolysis of Ambra1 during apoptosis has a role in the inhibition of the autophagic pro-survival response by Pagliarini, V, Wirawan, E, Romagnoli, A, Ciccosanti, F, Lisi, G, Lippens, S, Cecconi, F, Fimia, G M, Vandenabeele, P, Corazzari, M, Piacentini, M

“…Under stress conditions, pro-survival and pro-death processes are concomitantly activated and the final outcome depends on the complex crosstalk between these…”
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An overview of state‐of‐the‐art image restoration in electron microscopy by ROELS, J., AELTERMAN, J., LUONG, H.Q., LIPPENS, S., PIŽURICA, A., SAEYS, Y., PHILIPS, W.

“…Summary In Life Science research, electron microscopy (EM) is an essential tool for morphological analysis at the subcellular level as it allows for…”
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A workflow for 3D‐CLEM investigating liver tissue by KREMER, A., VAN HAMME, E., BONNARDEL, J., BORGHGRAEF, P., GUÉRIN, C.J., GUILLIAMS, M., LIPPENS, S.

“…Summary Correlative light and electron microscopy (CLEM) is a method used to investigate the exact same region in both light and electron microscopy (EM) in…”
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Death penalty for keratinocytes: apoptosis versus cornification by Lippens, S, Denecker, G, Ovaere, P, Vandenabeele, P, Declercq, W

“…Homeostasis implies a balance between cell growth and cell death. This balance is essential for the development and maintenance of multicellular organisms…”
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Unravelling the ultrastructural details of αT‐catenin‐deficient cell–cell contacts between heart muscle cells by the use of FIB‐SEM by VANSLEMBROUCK, B., KREMER, A., VAN ROY, F., LIPPENS, S., VAN HENGEL, J.

“…Summary The intercalated disc is an important structure in cardiomyocytes, as it is essential to maintain correct contraction and proper functioning of the…”
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A novel RIPK4–IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes by De Groote, P, Tran, H T, Fransen, M, Tanghe, G, Urwyler, C, De Craene, B, Leurs, K, Gilbert, B, Van Imschoot, G, De Rycke, R, Guérin, C J, Holland, P, Berx, G, Vandenabeele, P, Lippens, S, Vleminckx, K, Declercq, W

“…Receptor-interacting protein kinase 4 (RIPK4)-deficient mice have epidermal defects and fusion of all external orifices. These are similar to Bartsocas–Papas…”
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Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis by Lippens, S, Lefebvre, S, Gilbert, B, Sze, M, Devos, M, Verhelst, K, Vereecke, L, Guire, C Mc, Guérin, C, Vandenabeele, P, Pasparakis, M, Mikkola, M L, Beyaert, R, Declercq, W, van Loo, G

“…The ubiquitin-editing enzyme A20 (tumor necrosis factor- α -induced protein 3) serves as a critical brake on nuclear factor κ B (NF- κ B) signaling. In humans,…”
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Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing by Lippens, S, Kockx, M, Knaapen, M, Mortier, L, Polakowska, R, Verheyen, A, Garmyn, M, Zwijsen, A, Formstecher, P, Huylebroeck, D, Vandenabeele, P, Declercq, W

“…The epidermis is a stratified squamous epithelium in which keratinocytes progressively undergo terminal differentiation towards the skin surface leading to…”
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Regulation of PIDD auto-proteolysis and activity by the molecular chaperone Hsp90 by Tinel, A, Eckert, M J, Logette, E, Lippens, S, Janssens, S, Jaccard, B, Quadroni, M, Tschopp, J

“…In response to DNA damage, p53-induced protein with a death domain (PIDD) forms a complex called the PIDDosome, which either consists of PIDD, RIP-associated…”
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Caspase-14 is expressed in the epidermis, the choroid plexus, the retinal pigment epithelium and thymic Hassall's bodies by Lippens, S, VandenBroecke, C, Van Damme, E, Tschachler, E, Vandenabeele, P, Declercq, W

“…Cell Death and Differentiation (2003) 10, 257-259. doi:10.1038/sj.cdd.4401141…”
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PIDD Mediates NF-κB Activation in Response to DNA Damage by Janssens, Sophie, Tinel, Antoine, Lippens, Saskia, Tschopp, Jürg

“…Activation of NF-κB following genotoxic stress allows time for DNA-damage repair and ensures cell survival accounting for acquired chemoresistance, an…”
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An international survey of Training Needs and Career Paths of Core Facility Staff by Adami, Valentina, Homer, Natalie, Utz, Nadine, Lippens, Saskia, Rappoport, Joshua Z, Fernandez-Rodriguez, Julia

“…Core facilities (CFs) provide a centralised access to costly equipment, scientific expertise, experimental design, day-to-day technical support and training of…”
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A comparison of human and automatic musical genre classification by Lippens, S., Martens, J.P., De Mulder, T.

“…Recently there has been an increasing amount of work in the area of automatic genre classification of music in audio format. In addition to automatically…”
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Activation of p38 MAPK is required for Bax translocation to mitochondria, cytochrome c release and apoptosis induced by UVB irradiation in human keratinocytes by Van Laethem, An, Van Kelst, Sofie, Lippens, Saskia, Declercq, Wim, Vandenabeele, Peter, Janssens, Stefan, Vandenheede, Jackie R., Garmyn, Maria, Agostinis, Patrizia

“…This study establishes that activation of p38 MAPK by UVB represents a crucial signal required for the conformational change and translocation of Bax to the…”
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Terminal Differentiation of Human Keratinocytes and Stratum Corneum Formation is Associated with Caspase-14 Activation by Eckhart, Leopold, Declercq, Wim, Ban, Jozef, Rendl, Michael, Lengauer, Barbara, Mayer, Christoph, Lippens, Saskia, Vandenabeele, Peter, Tschachler, Erwin

“…Programmed cell death of epidermal keratinocytes (KC) results in the formation of cornified cells, which constitute the outermost skin layer, the stratum…”
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Cosmetische rostrale neusreconstructie na plaveiselcelcarcinoomresectie bij twee honden by Lippens, S., Van Goethem, B., Gielen, I., Polis, I., de Rooster, H.

“…Twee mannelijke golden retrievers van ongeveer tien jaar oud werden aangeboden met een zichtbare massa in de neus, niesden en vertoonden epistaxis. Uit…”
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Regulation of the Expression and Processing of Caspase-12 by Kalai, Michael, Lamkanfi, Mohamed, Denecker, Geertrui, Boogmans, Michael, Lippens, Saskia, Meeus, Ann, Declercq, Wim, Vandenabeele, Peter

“…Phylogenetic analysis clusters caspase-12 with the inflammatory caspases 1 and 11. We analyzed the expression of caspase-12 in mouse embryos, adult organs, and…”
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