Search Results - "LIPP, J"

SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis by Muhar, Matthias, Ebert, Anja, Neumann, Tobias, Umkehrer, Christian, Jude, Julian, Wieshofer, Corinna, Rescheneder, Philipp, Lipp, Jesse J, Herzog, Veronika A, Reichholf, Brian, Cisneros, David A, Hoffmann, Thomas, Schlapansky, Moritz F, Bhat, Pooja, von Haeseler, Arndt, Köcher, Thomas, Obenauf, Anna C, Popow, Johannes, Ameres, Stefan L, Zuber, Johannes

“…Defining direct targets of transcription factors and regulatory pathways is key to understanding their roles in physiology and disease. We combined SLAM-seq…”
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Single crystal toroidal diamond anvils for high pressure experiments beyond 5 megabar by Jenei, Zs, O’Bannon, E. F., Weir, S. T., Cynn, H., Lipp, M. J., Evans, W. J.

“…Static compression experiments over 4 Mbar are rare, yet critical for developing accurate fundamental physics and chemistry models, relevant to a range of…”
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Isolating live cell clones from barcoded populations using CRISPRa-inducible reporters by Umkehrer, Christian, Holstein, Felix, Formenti, Laura, Jude, Julian, Froussios, Kimon, Neumann, Tobias, Cronin, Shona M., Haas, Lisa, Lipp, Jesse J., Burkard, Thomas R., Fellner, Michaela, Wiesner, Thomas, Zuber, Johannes, Obenauf, Anna C.

“…We developed a functional lineage tracing tool termed CaTCH (CRISPRa tracing of clones in heterogeneous cell populations). CaTCH combines precise clonal…”
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Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin by Peters, Jan-Michael, Hirota, Toru, Lipp, Jesse J, Toh, Ban-Hock

“…Histones are subject to numerous post-translational modifications. Some of these 'epigenetic' marks recruit proteins that modulate chromatin structure. For…”
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P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates by Sansó, Miriam, Levin, Rebecca S, Lipp, Jesse J, Wang, Vivien Ya-Fan, Greifenberg, Ann Katrin, Quezada, Elizabeth M, Ali, Akbar, Ghosh, Animesh, Larochelle, Stéphane, Rana, Tariq M, Geyer, Matthias, Tong, Liang, Shokat, Kevan M, Fisher, Robert P

“…The transcription cycle of RNA polymerase II (Pol II) is regulated at discrete transition points by cyclin-dependent kinases (CDKs). Positive transcription…”
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Meiotic Prophase Requires Proteolysis of M Phase Regulators Mediated by the Meiosis-Specific APC/CAma1 by Okaz, Elwy, Argüello-Miranda, Orlando, Bogdanova, Aliona, Vinod, P.K., Lipp, Jesse J., Markova, Zuzana, Zagoriy, Ievgeniia, Novak, Bela, Zachariae, Wolfgang

“…Whereas proliferating cells enter M phase shortly after DNA replication, the first M phase of meiosis is preceded by an extended prophase in which homologous…”
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Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells by Lieb, Simone, Blaha-Ostermann, Silvia, Kamper, Elisabeth, Rippka, Janine, Schwarz, Cornelia, Ehrenhöfer-Wölfer, Katharina, Schlattl, Andreas, Wernitznig, Andreas, Lipp, Jesse J, Nagasaka, Kota, van der Lelij, Petra, Bader, Gerd, Koi, Minoru, Goel, Ajay, Neumüller, Ralph A, Peters, Jan-Michael, Kraut, Norbert, Pearson, Mark A, Petronczki, Mark, Wöhrle, Simon

“…Targeted cancer therapy is based on exploiting selective dependencies of tumor cells. By leveraging recent functional screening data of cancer cell lines we…”
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Compression-rate dependence of pressure-induced phase transitions in Bi by Husband, Rachel J., O’Bannon, Earl F., Liermann, Hanns-Peter, Lipp, Magnus J., Méndez, Alba S. J., Konôpková, Zuzana, McBride, Emma E., Evans, William J., Jenei, Zsolt

“…It is qualitatively well known that kinetics related to nucleation and growth can shift apparent phase boundaries from their equilibrium value. In this work,…”
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Rec8 Phosphorylation by Casein Kinase 1 and Cdc7-Dbf4 Kinase Regulates Cohesin Cleavage by Separase during Meiosis by Katis, Vittorio L., Lipp, Jesse J., Imre, Richard, Bogdanova, Aliona, Okaz, Elwy, Habermann, Bianca, Mechtler, Karl, Nasmyth, Kim, Zachariae, Wolfgang

“…During meiosis, two rounds of chromosome segregation after a single round of DNA replication produce haploid gametes from diploid precursors. At meiosis I,…”
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Dbf4-Dependent Cdc7 Kinase Links DNA Replication to the Segregation of Homologous Chromosomes in Meiosis I by Matos, Joao, Lipp, Jesse J., Bogdanova, Aliona, Guillot, Sylvine, Okaz, Elwy, Junqueira, Magno, Shevchenko, Andrej, Zachariae, Wolfgang

“…Meiosis differs from mitosis in that DNA replication is followed by the segregation of homologous chromosomes but not sister chromatids. This depends on the…”
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Prefrontal but not cerebellar tDCS attenuates renewal of extinguished conditioned eyeblink responses by Lipp, J., Draganova, R., Batsikadze, G., Ernst, T.M., Uengoer, M., Timmann, D.

“…•No direct effects of dlPFC or cerebellar tDCS on extinction of conditioned eyeblinks.•Anodal tDCS of dlPFC during extinction attenuated renewal…”
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Dynamic compression of Ce and Pr with millisecond time-resolved X-ray diffraction by O’Bannon III, Earl F., Husband, Rachel J., Baer, Bruce J., Lipp, Magnus J., Liermann, Hanns-Peter, Evans, William J., Jenei, Zsolt

“…Both cerium (Ce) and praseodymium (Pr) undergo a volume collapse transition under compression that originate from similar electronic mechanisms. Yet the…”
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Anomalous elastic properties across the γ to α volume collapse in cerium by Lipp, Magnus J., Jenei, Zs, Cynn, H., Kono, Y., Park, C., Kenney-Benson, C., Evans, W. J.

“…The behavior of the f -electrons in the lanthanides and actinides governs important macroscopic properties but their pressure and temperature dependence is not…”
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MicroRNAs in blood act as biomarkers of colorectal cancer and indicate potential therapeutic targets by Stang, Axel, Weilert, Hauke, Lipp, Michael J., Oldhafer, Karl J., Hoheisel, Jörg D., Zhang, Chaoyang, Bauer, Andrea S.

“…Association studies have linked alterations of blood‐derived microRNAs (miRNAs) with colorectal cancer (CRC). Here, we performed a microarray‐based comparison…”
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Genetic dependencies associated with transcription factor activities in human cancer cell lines by Thatikonda, Venu, Supper, Verena, Wachter, Johannes, Kaya, Onur, Kombara, Anju, Bilgilier, Ceren, Ravichandran, Madhwesh C., Lipp, Jesse J., Sharma, Rahul, Badertscher, Lukas, Boghossian, Andrew S., Rees, Matthew G., Ronan, Melissa M., Roth, Jennifer A., Grosche, Sarah, Neumüller, Ralph A., Mair, Barbara, Mauri, Federico, Popa, Alexandra

“…Transcription factors (TFs) are important mediators of aberrant transcriptional programs in cancer cells. In this study, we focus on TF activity (TFa) as a…”
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Thermal signatures of the Kondo volume collapse in cerium by Lipp, M J, Jackson, D, Cynn, H, Aracne, C, Evans, W J, McMahan, A K

“…X-ray diffraction measurements of cerium in the vicinity of the isostructural gamma-alpha transition have been performed with high precision and accuracy from…”
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Functional and molecular characterization of PD1+ tumor-infiltrating lymphocytes from lung cancer patients by Lipp, Jesse J., Wang, Limei, Yang, Haitang, Yao, Feng, Harrer, Nathalie, Müller, Stefan, Berezowska, Sabina, Dorn, Patrick, Marti, Thomas M., Schmid, Ralph A., Hegedüs, Belazs, Souabni, Abdallah, Carotta, Sebastian, Pearson, Mark A., Sommergruber, Wolfgang, Kocher, Greg J., Hall, Sean R.R.

“…Antibody-mediated cancer immunotherapy targets inhibitory surface molecules, such as PD1, PD-L1, and CTLA-4, aiming to re-invigorate dysfunctional T cells. We…”
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Dynamic diamond anvil cell (dDAC): a novel device for studying the dynamic-pressure properties of materials by Evans, William J, Yoo, Choong-Shik, Lee, Geun Woo, Cynn, Hyunchae, Lipp, Magnus J, Visbeck, Ken

“…We have developed a unique device, a dynamic diamond anvil cell (dDAC), which repetitively applies a time-dependent load/pressure profile to a sample. This…”
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Optimizing sample pretreatment for compound-specific stable carbon isotopic analysis of amino sugars in marine sediment by Zhu, R, Lin, Y.-S, Lipp, J. S, Meador, T. B, Hinrichs, K.-U

“…Amino sugars are quantitatively significant constituents of soil and marine sediment, but their sources and turnover in environmental samples remain poorly…”
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Genetic interaction mapping reveals a role for the SWI/SNF nucleosome remodeler in spliceosome activation in fission yeast by Patrick, Kristin L, Ryan, Colm J, Xu, Jiewei, Lipp, Jesse J, Nissen, Kelly E, Roguev, Assen, Shales, Michael, Krogan, Nevan J, Guthrie, Christine

“…Although numerous regulatory connections between pre-mRNA splicing and chromatin have been demonstrated, the precise mechanisms by which chromatin factors…”
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