Search Results - "LINONG ZHANG"

CX3CR1 Is Expressed in Differentiated Human Ciliated Airway Cells and Co-Localizes with Respiratory Syncytial Virus on Cilia in a G Protein-Dependent Manner by Jeong, Kwang-Il, Piepenhagen, Peter A, Kishko, Michael, DiNapoli, Joshua M, Groppo, Rachel P, Zhang, Linong, Almond, Jeffrey, Kleanthous, Harry, Delagrave, Simon, Parrington, Mark

“…Respiratory syncytial virus (RSV) is the principal cause of bronchiolitis in infants and a significant healthcare problem. The RSV Glycoprotein (G) mediates…”
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Mutations in the F protein of the live-attenuated respiratory syncytial virus vaccine candidate ΔNS2/Δ1313/I1314L increase the stability of infectivity and content of prefusion F protein by Alamares-Sapuay, Judith, Kishko, Michael, Lai, Charles, Parrington, Mark, Delagrave, Simon, Herbert, Richard, Castens, Ashley, Swerczek, Joanna, Luongo, Cindy, Yang, Lijuan, Collins, Peter L, Buchholz, Ursula J, Zhang, Linong

“…Respiratory syncytial virus (RSV) is the leading viral cause of bronchiolitis and pneumonia in infants and toddlers, but there currently is no licensed…”
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Effect of genetic background and delivery route on the preclinical properties of a live attenuated RSV vaccine by Groppo, Rachel, DiNapoli, Joshua, Il Jeong, Kwang, Kishko, Michael, Jackson, Nicholas, Kleanthous, Harold, Delagrave, Simon, Zhang, Linong, Parrington, Mark

“…A safe and effective vaccine against RSV remains an important unmet public health need. Intranasally (IN) delivered live-attenuated vaccines represent the most…”
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A novel vaccine adjuvant based on straight polyacrylate potentiates vaccine-induced humoral and cellular immunity in cynomolgus macaques by Pavot, Vincent, Bisceglia, Hélène, Guillaume, Florine, Montano, Sandrine, Zhang, Linong, Boudet, Florence, Haensler, Jean

“…Adjuvants are central to the efficacy of subunit vaccines. Although several new adjuvants have been approved in human vaccines over the last decade, the panel…”
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Core bead chromatography for preparation of highly pure, infectious respiratory syncytial virus in the negative purification mode by Mundle, Sophia T, Kishko, Michael, Groppo, Rachel, DiNapoli, Joshua, Hamberger, John, McNeil, Bryan, Kleanthous, Harry, Parrington, Mark, Zhang, Linong, Anderson, Stephen F

“…Highlights • A purification procedure for respiratory syncytial virus is described. • Purification is achieved by core bead chromatography followed by…”
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Immunogenicity and protective efficacy of RSV G central conserved domain vaccine with a prefusion nanoparticle by Rainho-Tomko, Jennifer N., Pavot, Vincent, Kishko, Michael, Swanson, Kurt, Edwards, Darin, Yoon, Heesik, Lanza, Lilibeth, Alamares-Sapuay, Judith, Osei-Bonsu, Robert, Mundle, Sophia T., Murison, Dave A., Gallichan, Scott, Delagrave, Simon, Wei, Chih-Jen, Zhang, Linong, Nabel, Gary J.

“…Respiratory syncytial virus (RSV) G glycoprotein has recently reemerged as a vaccine antigen due to its ability to elicit potent neutralizing antibodies and…”
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Application of replication-defective West Nile virus vector to non-flavivirus vaccine targets by Giel-Moloney, Maryann, Vaine, Michael, Zhang, Linong, Parrington, Mark, Gajewska, Beata, Vogel, Thorsten U., Pougatcheva, Svetlana O., Duan, Xiaochu, Farrell, Timothy, Ustyugova, Irina, Phogat, Sanjay, Kleanthous, Harry, Pugachev, Konstantin V.

“…The RepliVax vaccine platform(RV) is based on flavivirus genomes that are rationally attenuated by deletion. The self-limiting infection provided by RV has…”
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Preclinical Qualification of a New Multi-antigen Candidate Vaccine for Metastatic Melanoma by VOGEL, Thorsten U, VISAN, Lucian, MCNEIL, Bryan, SANDHU, Devender, SCOLLARD, Nancy, LINONG ZHANG, BRADLEY, Bill, MEI TANG, LOVITT, Corey, OOMEN, Ray, DUNN, Pamela, TARTAGLIA, Jim, LJUTIC, Belma, BERINSTEIN, Neil L, GAJEWSKA, Beata, CATERINI, Judy, SALHA, Danielle, TAO WEN, LIWEI HE, PARRINGTON, Mark, CAO, Shi-Xian

“…New therapies are urgently required for the treatment of patients with melanoma. Here we describe the generation and preclinical evaluation of 3 new…”
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Evaluation of the respiratory syncytial virus G-directed neutralizing antibody response in the human airway epithelial cell model by Kishko, Michael, Catalan, John, Swanson, Kurt, DiNapoli, Josh, Wei, Chih-Jen, Delagrave, Simon, Chivukula, Sudha, Zhang, Linong

“…Human respiratory syncytial virus (RSV) is a major cause of serious respiratory tract infections in infants and the elderly. Recently it was shown that the RSV…”
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Mutations in the F protein of the live-attenuated respiratory syncytial virus vaccine candidate [DELTA]NS2/[DELTA]1313/I1314L increase the stability of infectivity and content of prefusion F protein by Alamares-Sapuay, Judith, Kishko, Michael, Lai, Charles, Parrington, Mark, Delagrave, Simon, Herbert, Richard, Castens, Ashley, Swerczek, Joanna, Luongo, Cindy, Yang, Lijuan, Collins, Peter L, Buchholz, Ursula J, Zhang, Linong

“…Respiratory syncytial virus (RSV) is the leading viral cause of bronchiolitis and pneumonia in infants and toddlers, but there currently is no licensed…”
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A respiratory syncytial virus (RSV) F protein nanoparticle vaccine focuses antibody responses to a conserved neutralization domain by Swanson, Kurt A, Rainho-Tomko, Jennifer N, Williams, Zachary P, Lanza, Lilibeth, Peredelchuk, Michael, Kishko, Michael, Pavot, Vincent, Alamares-Sapuay, Judith, Adhikarla, Haritha, Gupta, Sankalp, Chivukula, Sudha, Gallichan, Scott, Zhang, Linong, Jackson, Nicholas, Yoon, Heesik, Edwards, Darin, Wei, Chih-Jen, Nabel, Gary J

“…A stabilized form of the respiratory syncytial virus (RSV) fusion (F) protein has been explored as a vaccine to prevent viral infection because it presents…”
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Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus by Rush, Scott A., Brar, Gurpreet, Hsieh, Ching-Lin, Chautard, Emilie, Rainho-Tomko, Jennifer N., Slade, Chris D., Bricault, Christine A., Kume, Ana, Kearns, James, Groppo, Rachel, Mundle, Sophia T., Zhang, Linong, Casimiro, Danilo, Fu, Tong-Ming, DiNapoli, Joshua M., McLellan, Jason S.

“…Human metapneumovirus (hMPV) is a major cause of acute respiratory infections in infants and older adults, for which no vaccines or therapeutics are available…”
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Presumed Risk Factors and Biomarkers for Severe Respiratory Syncytial Virus Disease and Related Sequelae: Protocol for an Observational Multicenter, Case-Control Study From the Respiratory Syncytial Virus Consortium in Europe (RESCEU) by Jefferies, Kimberley, Drysdale, Simon B, Robinson, Hannah, Clutterbuck, Elizabeth Ann, Blackwell, Luke, McGinley, Joseph, Lin, Gu-Lung, Galal, Ushma, Nair, Harish, Aerssens, Jeroen, Öner, Deniz, Langedijk, Annefleur, Bont, Louis, Wildenbeest, Joanne G, Martinon-Torres, Federico, Rodríguez-Tenreiro Sánchez, Carmen, Nadel, Simon, Openshaw, Peter, Thwaites, Ryan, Widjojoatmodjo, Myra, Zhang, Linong, Nguyen, Thi Lien-Anh, Giaquinto, Carlo, Giordano, Giuseppe, Baraldi, Eugenio, Pollard, Andrew J

“…Abstract Respiratory syncytial virus (RSV) is the leading viral pathogen associated with acute lower respiratory tract infection and hospitalization in…”
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Mutations in the F protein of the live-attenuated respiratory syncytial virus vaccine candidate ΔNS2/Δ1313/I1314L increase the stability of infectivity and content of prefusion F protein by Judith Alamares-Sapuay, Michael Kishko, Charles Lai, Mark Parrington, Simon Delagrave, Richard Herbert, Ashley Castens, Joanna Swerczek, Cindy Luongo, Lijuan Yang, Peter L. Collins, Ursula J. Buchholz, Linong Zhang

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CX3CR1 Is Expressed in Differentiated Human Ciliated Airway Cells and Co-Localizes with Respiratory Syncytial Virus on Cilia in a G Protein-Dependent Manner: e0130517 by Jeong, Kwang-Il, Piepenhagen, Peter A, Kishko, Michael, DiNapoli, Joshua M, Groppo, Rachel P, Zhang, Linong, Almond, Jeffrey, Kleanthous, Harry, Delagrave, Simon, Parrington, Mark

“…Respiratory syncytial virus (RSV) is the principal cause of bronchiolitis in infants and a significant healthcare problem. The RSV Glycoprotein (G) mediates…”
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Evaluation of promoters for foreign gene expression in the E3 region of bovine adenovirus type-3 by Zhang, Linong, Gomis, Susantha, Tikoo, Suresh K.

“…In order to optimize foreign gene expression in the E3 region of BAdV-3, we constructed full-length BAdV-3 genomic DNA clones containing a reporter gene…”
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The Himar1 mariner transposase cloned in a recombinant adenovirus vector is functional in mammalian cells by Zhang, Linong, Sankar, Uma, Lampe, David J., Robertson, Hugh M., Graham, Frank L.

“…Mariner transposons belong to the mariner/Tc1 superfamily of class II, DNA-mediated elements. One of these transposons, Himar1, isolated from the horn fly, is…”
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Identification of cis-acting sequences required for selective packaging of bovine adenovirus type 3 DNA by Xing, Li, Zhang, Linong, Kessel, Jill Van, Tikoo, Suresh Kumar

“…Vaccine and Infectious Disease Organization, University of Saskatchewan, 120-Veterinary Road, Saskatoon, SK, Canada S7N 5E3 Correspondence Suresh Kumar Tikoo…”
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Recombinant Genomic RNA of Coronavirus MHV-A59 after Coreplication with a DI RNA Containing the MHV-RI Spike Gene by Zhang, Linong, Homberger, Felix, Spaan, Willy, Luytjes, Willem

“…A strategy for targeted RNA recombination between the spike gene on the genomic RNA of MHV-A59 and a synthetic DI RNA containing the MHV-RI spike gene is…”
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Molecular characterization of the S proteins of two enterotropic murine coronavirus strains by Kunita, Satoshi, Zhang, Linong, Homberger, Felix R., Compton, Susan R.

“…Enterotropic strains of murine coronaviruses (MHV-Y and MHV-RI) differ extensively in their pathogenesis from the prototypic respiratory strains of murine…”
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