Search Results - "LINKESCH, Werner"

Human platelet lysate can replace fetal bovine serum for clinical-scale expansion of functional mesenchymal stromal cells by Schallmoser, Katharina, Bartmann, Christina, Rohde, Eva, Reinisch, Andreas, Kashofer, Karl, Stadelmeyer, Elke, Drexler, Camilla, Lanzer, Gerhard, Linkesch, Werner, Strunk, Dirk

“…BACKGROUND: Human multipotent mesenchymal stromal cells (MSCs) are promising candidates for a growing spectrum of regenerative and immunomodulatory cellular…”
Get full text

Impact of ATG-containing reduced-intensity conditioning after single- or double-unit allogeneic cord blood transplantation by Pascal, Laurent, Tucunduva, Luciana, Ruggeri, Annalisa, Blaise, Didier, Ceballos, Patrice, Chevallier, Patrice, Cornelissen, Jan, Maillard, Natacha, Tabrizi, Reza, Petersen, Eefke, Linkesch, Werner, Sengeloev, Henrik, Kenzey, Chantal, Pagliuca, Antonio, Holler, Ernst, Einsele, Hermann, Gluckman, Eliane, Rocha, Vanderson, Yakoub-Agha, Ibrahim

“…We analyzed 661 adult patients who underwent single-unit (n = 226) or double-unit (n = 435) unrelated cord blood transplantation (UCBT) following a…”
Get full text

Humanized large-scale expanded endothelial colony–forming cells function in vitro and in vivo by Reinisch, Andreas, Hofmann, Nicole A., Obenauf, Anna C., Kashofer, Karl, Rohde, Eva, Schallmoser, Katharina, Flicker, Karin, Lanzer, Gerhard, Linkesch, Werner, Speicher, Michael R., Strunk, Dirk

“…Endothelial progenitor cells are critically involved in essential biologic processes, such as vascular homeostasis, regeneration, and tumor angiogenesis…”
Get full text

Blood Monocytes Mimic Endothelial Progenitor Cells by Rohde, Eva, Malischnik, Christina, Thaler, Daniela, Maierhofer, Theresa, Linkesch, Werner, Lanzer, Gerhard, Guelly, Christian, Strunk, Dirk

“…The generation of endothelial progenitor cells (EPCs) from blood monocytes has been propagated as a novel approach in the diagnosis and treatment of…”
Get full text

Vinorelbine as substitute for vincristine in patients with diffuse large B cell lymphoma and vincristine-induced neuropathy by Hatzl, Stefan, Posch, Florian, Rezai, Arwin, Gornicec, Maximilian, Beham-Schmid, Christine, Magnes, Theresa, Wangner, Sandro, Deutsch, Alexander, Greinix, Hildegard, Uhl, Barbara, Prochazka, Katharina T., Egle, Alexander, Greil, Richard, Melchardt, Thomas, Linkesch, Werner, Schulz, Eduard, Neumeister, Peter

“…Background A combination of rituximab with cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) is the standard first-line therapy for diffuse…”
Get full text

Immune Cells Mimic the Morphology of Endothelial Progenitor Colonies In Vitro by Rohde, Eva, Bartmann, Christina, Schallmoser, Katharina, Reinisch, Andreas, Lanzer, Gerhard, Linkesch, Werner, Guelly, Christian, Strunk, Dirk

“…Endothelial progenitor cells (EPC) are considered powerful biologic markers for vascular function and cardiovascular risk, predicting events and death from…”
Get full text

Two steps to functional mesenchymal stromal cells for clinical application by Bartmann, Christina, Rohde, Eva, Schallmoser, Katharina, Pürstner, Peter, Lanzer, Gerhard, Linkesch, Werner, Strunk, Dirk

“…BACKGROUND: Ex vivo expansion of multipotent mesenchymal stromal cells (MSCs) is a prerequisite for evaluating their therapeutic potential in ongoing clinical…”
Get full text

Rapid large-scale expansion of functional mesenchymal stem cells from unmanipulated bone marrow without animal serum by Schallmoser, Katharina, Rohde, Eva, Reinisch, Andreas, Bartmann, Christina, Thaler, Daniela, Drexler, Camilla, Obenauf, Anna C, Lanzer, Gerhard, Linkesch, Werner, Strunk, Dirk

“…Adult mesenchymal stem cells (MSCs) are considered as valuable mediators for tissue regeneration and cellular therapy. This study was performed to develop…”
Get more information

Rituximab plus subcutaneous cladribine in patients with extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue: a phase II study by the Arbeitsgemeinschaft Medikamentöse Tumortherapie by Troch, Marlene, Kiesewetter, Barbara, Willenbacher, Wolfgang, Willenbacher, Ella, Zebisch, Armin, Linkesch, Werner, Fridrik, Michael, Müllauer, Leonhard, Greil, Richard, Raderer, Markus

“…Currently, there is no standard systemic treatment for extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue. Both rituximab and…”
Get full text

Humanized system to propagate cord blood-derived multipotent mesenchymal stromal cells for clinical application by Reinisch, Andreas, Bartmann, Christina, Rohde, Eva, Schallmoser, Katharina, Bjelic-Radisic, Vesna, Lanzer, Gerhard, Linkesch, Werner, Strunk, Dirk

“…Umbilical cord blood (UCB) is an easily accessible alternative source for multipotent mesenchymal stromal cells (MSCs) and is generally believed to provide…”
Get more information

Frequency, onset and clinical impact of somatic DNMT3A mutations in therapy-related and secondary acute myeloid leukemia by FRIED, Isabella, BODNER, Claudia, PICHLER, Monika M, LIND, Karin, BEHAM-SCHMID, Christine, QUEHENBERGER, Franz, SPERR, Wolfgang R, LINKESCH, Werner, SILL, Heinz, WÖLFLER, Albert

“…The recent identification of DNMT3A mutations in de novo acute myeloid leukemia prompted us to determine their frequency, patterns and clinical impact in a…”
Get full text

The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling by Staber, Philipp B., Vesely, Paul, Haq, Naznin, Ott, Rene G., Funato, Kotaro, Bambach, Isabella, Fuchs, Claudia, Schauer, Silvia, Linkesch, Werner, Hrzenjak, Andelko, Dirks, Wilhelm G., Sexl, Veronika, Bergler, Helmut, Kadin, Marshall E., Sternberg, David W., Kenner, Lukas, Hoefler, Gerald

“…Anaplastic large cell lymphomas (ALCLs) are highly proliferating tumors that commonly express the AP-1 transcription factor JunB. ALK fusions occur in…”
Get full text

MALT lymphoma and extranodal diffuse large B-cell lymphoma are targeted by aberrant somatic hypermutation by Deutsch, Alexander J.A., Aigelsreiter, Ariane, Staber, Philipp B., Beham, Alfred, Linkesch, Werner, Guelly, Christian, Brezinschek, Ruth I., Fruhwirth, Margareta, Emberger, Werner, Buettner, Maike, Beham-Schmid, Christine, Neumeister, Peter

“…Recently, a novel mechanism introducing genetic instability, termed aberrant somatic hypermutation (ASHM), has been described in diffuse large B-cell lymphoma…”
Get full text

Treatment of Extranodal Marginal Zone B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue Type With Cladribine: A Phase II Study by JÄGER, Gerald, NEUMEISTER, Peter, CHOTT, Andreas, BEHAM-SCHMID, Christine, HOLLER, Gerald, LINKESCH, Werner, RADERER, Markus, BREZINSCHEK, Ruth, HINTERLEITNER, Thomas, FIEBIGER, Wolfgang, PENZ, Melitta, NEUMANN, Hans J, MLINERITSCH, Brigitte, DESANTIS, Maria, QUEHENBERGER, Franz

“…As chemotherapy has not been extensively studied in patients with lymphoma of the mucosa-associated lymphoid tissue (MALT), we initiated a prospective study to…”
Get full text

90Yttrium-Ibritumomab-Tiuxetan as First-Line Treatment for Follicular Lymphoma: 30 Months of Follow-Up Data From an International Multicenter Phase II Clinical Trial by SCHOLZ, Christian W, PINTO, Antonello, ARCAMONE, Manuela, STROUX, Andrea, FRERICKS, Bernd, POTT, Christiane, PEZZUTTO, Antonio, LINKESCH, Werner, LINDEN, Ola, VIARDOT, Andreas, KELLER, Ulrich, HESS, Georg, LASTORIA, Secondo, LERCH, Kristina, FRIGERI, Ferdinando

“…PURPOSEWe report on a multicenter phase II trial of (90)yttrium-ibritumomab-tiuxetan ((90)YIT) as first-line stand-alone therapy for patients with follicular…”
Get full text

Histiocytic sarcoma - targeted therapy: novel therapeutic options? A series of 4 cases by Schlick, Konstantin, Aigelsreiter, Ariane, Pichler, Martin, Reitter, Sonja, Neumeister, Peter, Hoefler, Gerald, Beham-Schmid, Christine, Linkesch, Werner

“…Histiocytic sarcoma (HS) is a rare but highly aggressive disease. The cancer-specific survival of patients with HS is short and only limited response to…”
Get more information

Common alterations in gene expression and increased proliferation in recurrent acute myeloid leukemia by STABER, Philipp Bernhard, LINKESCH, Werner, ZAUNER, Dorothea, BEHAM-SCHMID, Christine, GUELLY, Christian, SCHAUER, Silvia, SILL, Heinz, HOEFLER, Gerald

“…Recurrent disease following high-dose chemotherapy is a major problem in patients with acute myeloid leukemia (AML). To identify its characteristics, we…”
Get full text

Pharmacokinetics, bioequivalence, tolerability, and effects on platelet counts of two formulations of anagrelide in healthy volunteers and patients with thrombocythemia associated with chronic myeloproliferation by Petrides, Petro E., MD, PhD, Gisslinger, Heinz, MD, Steurer, Michael, MD, Linkesch, Werner, MD, Krumpl, Günther, MD, Schüller, Agnes, MPharmSci, Widmann, Rudolf, PhD

“…Abstract Background: Anagrelide hydrochloride is an anti-thrombotic agent indicated for the treatment of essential thrombocythemia (ET). In various previously…”
Get full text

Roscovitine in B-chronic lymphocytic leukemia cells: high apoptosis-inducing efficacy and synergism with alemtuzumab independent of the patients' pretreatment status by Weingrill, Eva, Wolfler, Albert, Strunk, Dirk, Linkesch, Werner, Sill, Heinz, Liebmann, Peter M

“…* Division of Hematology, Department of Internal Medicine ° Institute of Pathophysiology, Medical University Graz, Austria Correspondence: Peter M. Liebmann,…”
Get full text

Bendamustine-bortezomib-dexamethasone is an active and well-tolerated regimen in patients with relapsed or refractory multiple myeloma by Ludwig, Heinz, Kasparu, Hedwig, Leitgeb, Clemens, Rauch, Elisabeth, Linkesch, Werner, Zojer, Niklas, Greil, Richard, Seebacher, Adelheid, Pour, Ludek, Weißmann, Adalbert, Adam, Zdeněk

“…Bendamustine with bortezomib and dexamethasone was evaluated in 79 patients with relapsed/refractory multiple myeloma. Median age was 64 years, and patients…”
Get full text