Search Results - "LINGE, Claire"

Sunscreens Inadequately Protect Against Ultraviolet-A-Induced Free Radicals in Skin: Implications for Skin Aging and Melanoma? by Haywood, Rachel, Wardman, Peter, Sanders, Roy, Linge, Claire

“…Sunscreens are employed to mitigate the adverse effects of sunlight on skin but are primarily designed to prevent ultraviolet-B-associated burning and damage…”
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Differential gene expression in response to transforming growth factor-β1 by fetal and postnatal dermal fibroblasts by Rolfe, Kerstin J., Irvine, Laurie M., Grobbelaar, Addie O., Linge, Claire

“…ABSTRACT The multipotent growth factor transforming growth factor (TGF)‐β1 is consistently linked with fibrosis and scarring. The perfect (scarless) healing of…”
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Purinergic receptors are part of a functional signaling system for proliferation and differentiation of human epidermal keratinocytes by GREIG, Aina V. H, LINGE, Claire, TERENGHI, Giorgio, MCGROUTHER, D. Angus, BURNSTOCK, Geoffrey

“…We investigated the expression of P2X5, P2X7, P2Y1 and P2Y2 receptor subtypes in normal human epidermis and in relation to markers of proliferation (PCNA and…”
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Purinergic Receptors Are Part of a Signaling System for Keratinocyte Proliferation, Differentiation, and Apoptosis in Human Fetal Epidermis by Greig, Aina V.H., Linge, Claire, Cambrey, Alison, Burnstock, Geoffrey

“…We have investigated the expression of P2X5, P2X7, P2Y1, and P2Y2 receptor subtypes in 8- to 11-wk-old human fetal epidermis in relation to markers of…”
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Dermal fibroblasts derived from fetal and postnatal humans exhibit distinct responses to insulin like growth factors by Rolfe, Kerstin J, Cambrey, Alison D, Richardson, Janette, Irvine, Laurie M, Grobbelaar, Adriaan O, Linge, Claire

“…It has been well established that human fetuses will heal cutaneous wounds with perfect regeneration. Insulin-like growth factors are pro-fibrotic fibroblast…”
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Synthetic melanin is a model for soluble natural eumelanin in UVA-photosensitised superoxide production by Haywood, Rachel M., Lee, Martin, Linge, Claire

“…Studies to UV-irradiate natural eumelanins in vitro have used insoluble pigment obtained by acid hydrolysis, which lacks melanoprotein. Eumelanin synthesised…”
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Cutaneous Scarring: A Clinical Review by Baker, Richard, Urso-Baiarda, Fulvio, Linge, Claire, Grobbelaar, Adriaan O.

“…Cutaneous scarring can cause patients symptoms ranging from the psychological to physical pain. Although the process of normal scarring is well described the…”
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Ruby laser-assisted hair removal success in relation to anatomic factors and melanin content of hair follicles by LIEW, S. H, LADHANI, K, GROBBELAAR, A. O, GAULT, D. T, SANDERS, R, GREEN, C. J, LINGE, C

“…Ruby laser-assisted hair removal is thought to work via selective photothermolysis, which relies on light reaching the deeper layers of skin, and the…”
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The effect of ruby laser light on ex vivo hair follicles: clinical implications by Liew, S H, Grobbelaar, A O, Gault, D T, Sanders, R, Green, C J, Linge, C

“…Several clinical studies on the efficacy of ruby laser-assisted hair removal have reported that regrowth of hair after treatment is common. One of the reasons…”
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A Role for TGF-β1-Induced Cellular Responses during Wound Healing of the Non-Scarring Early Human Fetus? by Rolfe, Kerstin J., Richardson, Janette, Vigor, Charlotte, Irvine, Laurie M., Grobbelaar, Addie O., Linge, Claire

“…Early human fetuses regenerate cutaneous wounds perfectly without scarring. However, transforming growth factor-β1 (TGF-β1), the cytokine linked with scarring…”
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Establishment and maintenance of normal human keratinocyte cultures by Linge, Claire

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Hypertrophic Scar Cells Fail to Undergo a Form of Apoptosis Specific to Contractile Collagen—The Role of Tissue Transglutaminase by Linge, Claire, Richardson, Janette, Vigor, Charlotte, Clayton, Elisabeth, Hardas, Bushan, Rolfe, Kerstin J.

“…Failure of apoptosis has been postulated to cause the hypercellularity and thus excess scar-tissue formation of hypertrophic scars (HTS). Here, we have…”
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Differential gene expression in response to transforming growth factor- beta 1 by fetal and postnatal dermal fibroblasts by Rolfe, Kerstin J, Irvine, Laurie M, Grobbelaar, Addie O, Linge, Claire

“…The multipotent growth factor transforming growth factor (TGF)- beta 1 is consistently linked with fibrosis and scarring. The perfect (scarless) healing of…”
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Expression of Purinergic Receptors in Non-melanoma Skin Cancers and Their Functional Roles in A431 Cells by Greig, Aina V.H., Burnstock, Geoffrey, Linge, Claire, Healy, Vourneen, Lim, Philip, Clayton, Elizabeth, Rustin, Malcolm H.A., Angus McGrouther, D.

“…We investigated the use of purinergic receptors as a new treatment modality for nonmelanoma skin cancers. Purinergic receptors, which bind adenosine…”
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An investigation to optimize angiogenesis within potential dermal replacements by POTTER, Matthew J, LINGE, Claire, CUSSONS, Paul, DYE, Julian F, SANDERS, Roy

“…Acute and chronic wounds are costly and invariably expose significant structures. Surgical reconstruction causes donor-site morbidity, scarring, and the need…”
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In vitro optimisation of topical negative pressure regimens for angiogenesis into synthetic dermal replacements by J. Potter, Matthew, Banwell, Paul, Baldwin, Christopher, Clayton, Elizabeth, Irvine, Laurie, Linge, Claire, Grobbelaar, Addrian O, Sanders, Roy, Dye, Julian F

“…Abstract Background The use of synthetic dermal replacements (SDRs) in the treatment of large wounds, which have associated morbidity and mortality, has…”
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A Role for TGF-[beta]1-Induced Cellular Responses during Wound Healing of the Non-Scarring Early Human Fetus? by Rolfe, Kerstin J, Richardson, Janette, Vigor, Charlotte, Irvine, Laurie M, Grobbelaar, Addie O, Linge, Claire

“…Early human fetuses regenerate cutaneous wounds perfectly without scarring. However, transforming growth factor-beta1 (TGF-beta1), the cytokine linked with…”
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Purinergic receptors are part of a signalling system for proliferation and differentiation in distinct cell lineages in human anagen hair follicles by Greig, Aina V. H., Linge, Claire, Burnstock, Geoffrey

“…We investigated the expression of P2X 5 , P2X 7 , P2Y 1 and P2Y 2 receptor subtypes in adult human anagen hair follicles and in relation to markers of…”
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Differential gene expression in response to transforming growth factor-beta1 by fetal and postnatal dermal fibroblasts by Rolfe, Kerstin J, Irvine, Laurie M, Grobbelaar, Addie O, Linge, Claire

“…The multipotent growth factor transforming growth factor (TGF)-beta1 is consistently linked with fibrosis and scarring. The perfect (scarless) healing of…”
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Retrospective study of the association between hypertrophic burn scarring and bacterial colonization by BAKER, Richard H. J, TOWNLEY, William A, MCKEON, S, LINGE, Claire, VIJH, Vikram

“…Although the association between hypertrophic burn scarring and infection is well described, an association with colonization has not been established. This…”
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