Search Results - "LINEU KRITSKI, Afrânio"
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Bedaquiline versus injectable containing regimens for rifampicin-resistant and multidrug-resistant tuberculosis in a reference center in Brazil - a real-world evidence study using a retrospective design
Published in BMC infectious diseases (07-10-2024)“…Drug resistance (DR) is one of the several challenges to global tuberculosis (TB) control. The implementation of bedaquiline (BED) for DR-TB after more than 40…”
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Social determinants of health and catastrophic costs associated with the diagnosis and treatment of tuberculosis
Published in Jornal brasileiro de pneumologia (01-01-2020)“…The epidemiological relevance of tuberculosis is directly related to the socioeconomic profile of a given country. Vulnerability to tuberculosis is influenced…”
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REDbox: a comprehensive semantic framework for data collection and management in tuberculosis research
Published in Scientific reports (11-05-2023)“…Clinical research outcomes depend on the correct definition of the research protocol, the data collection strategy, and the data management plan. Furthermore,…”
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Tuberculosis among children and adolescents in Rio de Janeiro, Brazil – Focus on extrapulmonary disease
Published in International journal of infectious diseases (01-04-2021)“…•Extrapulmonary Tuberculosis (EPTB) is underrepresented among Tuberculosis (TB) patients.•Miliary TB and TB meningitis in young children are unrepresented in…”
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Clinical Features and Treatment Outcomes of Patients with Drug-Resistant and Drug-Sensitive Tuberculosis: A Historical Cohort Study in Porto Alegre, Brazil
Published in PloS one (09-08-2016)“…To evaluate the clinical features and treatment outcomes of patients with pulmonary tuberculosis, stratified by level of drug resistance. This was a historical…”
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Abandonment of Treatment for Latent Tuberculosis Infection and Socioeconomic Factors in Children and Adolescents: Rio De Janeiro, Brazil
Published in PloS one (05-05-2016)“…Routine data on the use of isoniazid preventive therapy (IPT) in children and adolescents are scarce in high tuberculosis (TB) burden countries. To describe…”
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Determination of NAT2 Genotypes in a Cohort of Patients with Suspected TB in the State of Rio de Janeiro
Published in Pharmaceutics (10-07-2024)“…The human N-acetyltransferase 2 enzyme, encoded by the gene, plays an important role in the metabolism of isoniazid, the main drug used to treat tuberculosis…”
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Cost analysis of GenoType® MTBDRplus and GenoType® MTBDRsl at the State Laboratory of São Paulo, Brazil
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2023)“…We aimed to evaluate the costs of GenoType® MTBDRplus and MTBDRsl incurred during the diagnosis of first- and second-line drug-resistant tuberculosis (TB) in…”
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Beyond goodwill and promises—urgent needs and opportunities to accelerate the fight against tuberculosis in Brazil
Published in Lancet Regional Health - Americas (Online) (01-02-2024)Get full text
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Gene-Xpert Ultra for the diagnosis of extrapulmonary tuberculosis in children and adolescents
Published in Revista do Instituto de Medicina Tropical de São Paulo (01-01-2022)“…This prospective study describes the use of Gene-Xpert Ultra for the diagnosis of extrapulmonary tuberculosis (EPTB) in children and adolescents, in Rio de…”
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The use of Gene-Xpert MTB RIF in the diagnosis of extrapulmonary tuberculosis in childhood and adolescence
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2020)“…INTRODUCTIONGene-Xpert MTB RIF (Xpert) is based on nucleic acid amplification by real-time polymerase chain reaction, which allows for the identification of…”
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Predictors of mortality among intensive care unit patients coinfected with tuberculosis and HIV
Published in Jornal brasileiro de pneumologia (01-04-2018)“…To identify factors predictive of mortality in patients admitted to the ICU with tuberculosis (TB)/HIV coinfection in the Manaus, Amazon Region. This was a…”
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The clinical and molecular diagnosis of childhood and adolescent pulmonary tuberculosis in referral centers
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2020)“…The diagnostic accuracy of Xpert MTB/RIF (Xpert) in pulmonary tuberculosis (PTB) in children is lower than in adults. In Brazil, the diagnosis of PTB is based…”
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The importance of audiometric monitoring in patients with multidrug-resistant tuberculosis
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-09-2017)“…A total of 771 cases of multidrug-resistant tuberculosis (MDR-TB) were reported in Brazil in 2014. Treatment of MDR-TB with aminoglycosides can produce serious…”
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Tuberculosis contact tracing among children and adolescent referred to children's hospital in Rio de Janeiro, Brazil
Published in The Brazilian journal of infectious diseases (01-05-2015)“…To describe the investigation of latent tuberculosis infection and indication for isoniazid preventive therapy in children and adolescents evaluated at the…”
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Evaluation of the Commercial Kit SIRE Nitratase for detecting resistant Mycobacterium tuberculosis in Brazil
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-07-2017)“…This study aimed to evaluate a new commercial kit, Kit SIRE Nitratase-PlastLabor, for testing the drug susceptibility of clinical Mycobacterium tuberculosis…”
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Completeness of tuberculosis reporting forms in five Brazilian capitals with a high incidence of the disease
Published in Jornal brasileiro de pneumologia (01-04-2013)“…The aim of this study was to evaluate the completeness of tuberculosis reporting forms in the greater metropolitan areas of five Brazilian capitals where the…”
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Sociodemographic and Clinical Factors Associated with Treatment Outcomes for Drug-resistant Tuberculosis
Published in The American journal of tropical medicine and hygiene (14-12-2022)“…Drug-resistant tuberculosis (DR-TB) continues to be a serious public health problem. The objective of this study was to evaluate the sociodemographic,…”
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