Search Results - "LINENBERGER, M. L"

CD33-directed therapy with gemtuzumab ozogamicin in acute myeloid leukemia: progress in understanding cytotoxicity and potential mechanisms of drug resistance by LINENBERGER, M. L

“…CD33 is expressed on the malignant blast cells in most cases of acute myeloid leukemia (AML) but not on normal hematopoietic pluripotent stem cells…”
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Transduction of Notch2 in feline leukemia virus-induced thymic lymphoma by Rohn, J.L. (University of Washington, Seattle, WA.), Lauring, A.S, Linenberger, M.L, Overbaugh, J

“…Feline leukemia virus (FeLV) is thought to induce neoplastic diseases in infected cats by a variety of mechanisms, including the transduction of host…”
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Fibrinogen Bellingham: A γ‐chain R275C substitution and a β‐promoter polymorphism in a thrombotic member of an asymptomatic family by Linenberger, M.L., Kindelan, J., Bennett, R.L., Reiner, A.P., Côté, H.C.F.

“…Congenital dysfibrinogenemia is a rare cause of unexplained thrombosis. However, most individuals with dysfibrinogenemia are asymptomatic, suggesting that…”
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Evolution of feline leukemia virus variant genomes with insertions, deletions, and defective envelope genes in infected cats with tumors by ROHN, J. L, LINENBERGER, M. L, HOOVER, E. A, OVERBAUGH, J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Evidence for the Maintenance of Hematopoiesis in a Large Animal by the Sequential Activation of Stem-Cell Clones by Abkowitz, Janis L., Linenberger, Michael L., Newton, Michael A., Shelton, Grady H., Ott, Richard L., Guttorp, Peter

“…To test if hematopoiesis can be maintained by the sequential activation of stem-cell clones, we performed autologous marrow transplantations with limited…”
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Viral genetic variation, AIDS, and the multistep nature of carcinogenesis: the feline leukemia virus model by Rohn, J L, Gwynn, S R, Lauring, A S, Linenberger, M L, Overbaugh, J

“…Feline leukemia virus (FeLV) infection in cats serves as a valuable animal model system for understanding the mechanisms of human diseases such as cancer and…”
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Multidrug-resistance phenotype and clinical responses to gemtuzumab ozogamicin by Linenberger, Michael L., Hong, Tom, Flowers, David, Sievers, Eric L., Gooley, Ted A., Bennett, John M., Berger, Mark S., Leopold, Lance H., Appelbaum, Frederick R., Bernstein, Irwin D.

“…Expression of multidrug resistance (MDR) features by acute myeloid leukemia (AML) cells predicts a poor response to many treatments. The MDR phenotype often…”
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Hematologic manifestations of feline immunodeficiency virus infection by SHELTON, G. H, LINENBERGER, M. L, GRANT, C. K, ABKOWITZ, J. L

“…Studies were done on 53 cats with community-acquired infection with the feline immunodeficiency virus (FIV) to determine if hematologic abnormalities were…”
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Marrow Accessory Cell Infection and Alterations in Hematopoiesis Accompany Severe Neutropenia During Experimental Acute Infection With Feline Immunodeficiency Virus by Linenberger, Michael L., Beebe, Amy M., Pedersen, Niels C., Abkowitz, Janis L., Dandekar, Satya

“…Severe neutropenia and bone marrow (BM) morphologic abnormalities occur during experimentally induced primary infection with feline immunodeficiency virus…”
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In vivo infection of marrow stromal fibroblasts by feline leukemia virus by Linenberger, M L, Abkowitz, J L

“…Marrow stromal fibroblasts (FBs) likely play an important role in the regulation of hematopoiesis within the marrow microenvironment. Infection of these cells…”
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Breast cancer resistance protein (BCRP/ABCG2) does not confer resistance to gemtuzumab ozogamicin and calicheamicin-γ1 in acute myeloid leukemia cells by Walter, R B, Raden, B W, Thompson, J, Flowers, D A, Kiem, H-P, Bernstein, I D, Linenberger, M L

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Behavior of Feline Hematopoietic Stem Cells Years After Busulfan Exposure by Abkowitz, Janis L., Linenberger, Michael L., Persik, Monica, Newton, Michael A., Guttorp, Peter

“…The kinetics of hematopoietic stem cells were investigated in glucose-6-phosphate dehydrogenase (G-6-PD) heterozygous cats treated with dimethylbusulfan…”
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Studies in Feline Long-Term Marrow Culture: Hematopoiesis on Normal and Feline Leukemia Virus Infected Stromal Cells by Linenberger, Michael L., Abkowitz, Janis L.

“…To study the effects of feline leukemia virus (FeLV) on the hematopoietic microenvironment, a two-step feline long-term marrow culture (LTMC) system was…”
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Hematopoiesis in Asymptomatic Cats Infected With Feline Immunodeficiency Virus by Linenberger, Michael L., Shelton, Grady H., Persik, Monica T., Abkowitz, Janis L.

“…Anemia and neutropenia often develop in cats that are infected with the feline immunodeficiency virus (FIV), a lentivirus biologically similar to the human…”
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Hematologic abnormalities in cats seropositive for feline immunodeficiency virus by Shelton, G H, Linenberger, M L, Abkowitz, J L

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Antibody-directed therapies for hematological malignancies by Linenberger, Michael L, Maloney, David G, Bernstein, Irwin D

“…Malignant hematopoietic cells express lineage-restricted antigens that serve as suitable targets for antibody-directed therapy. Although several highly…”
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Chronic leukopenia associated with feline immunodeficiency virus infection in a cat by Shelton, G H, Abkowitz, J L, Linenberger, M L, Russell, R G, Grant, C K

“…Leukopenia attributable to lymphopenia and neutropenia was detected over a 28-week period in a 12-year-old domestic cat infected with feline immunodeficiency…”
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The effects of feline retroviruses on cytokine expression by Linenberger, Michael L, Deng, Ta

“…To identify potential roles of cytokines in retroviral pathogenesis, we used reverse transcription-quantitative competitive polymerase chain reaction…”
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Hematologic abnormalities associated with retroviral infections in the cat by Shelton, G H, Linenberger, M L

“…Feline patients with unexplained peripheral blood cytopenias, circulating immature or neoplastic cells, dysplastic or dysmorphic bone marrow abnormalities,…”
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Stem cell factor production by human marrow stromal fibroblasts by Linenberger, M L, Jacobson, F W, Bennett, L G, Broudy, V C, Martin, F H, Abkowitz, J L

“…To characterize the production of stem cell factor (SCF, the ligand for the c-kit receptor protein) and its regulation by inflammatory cytokines and…”
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