Search Results - "LINDNER, Veronique"
-
1
Thermoresponsive Gel Embedded with Adipose Stem-Cell-Derived Extracellular Vesicles Promotes Esophageal Fistula Healing in a Thermo-Actuated Delivery Strategy
Published in ACS nano (23-10-2018)“…Extracellular vesicles (EVs) are increasingly envisioned as the next generation of biological pro-regenerative nanotherapeutic agents, as has already been…”
Get full text
Journal Article -
2
Delineating the interplay between oncogenic pathways and immunity in anaplastic Wilms tumors
Published in Nature communications (30-11-2023)“…Wilms tumors are highly curable in up to 90% of cases with a combination of surgery and radio-chemotherapy, but treatment-resistant types such as diffuse…”
Get full text
Journal Article -
3
Immune-Desert Tumor Microenvironment in Thoracic SMARCA4-Deficient Undifferentiated Tumors with Limited Efficacy of Immune Checkpoint Inhibitors
Published in The oncologist (Dayton, Ohio) (08-06-2022)“…Thoracic SMARCA4-deficient undifferentiated tumors (SMARCA4-UT) are aggressive neoplasms. Data linking BAF alterations with tumor microenvironment (TME) and…”
Get full text
Journal Article -
4
The Lim1 oncogene as a new therapeutic target for metastatic human renal cell carcinoma
Published in Oncogene (01-01-2019)“…Metastatic clear cell renal cell carcinoma (CCC) remains incurable despite advances in the development of anti-angiogenic targeted therapies and the emergence…”
Get full text
Journal Article -
5
HYPerspectral Enhanced Reality (HYPER): a physiology-based surgical guidance tool
Published in Surgical endoscopy (01-04-2020)“…Background HSI is an optical technology allowing for a real-time, contrast-free snapshot of physiological tissue properties, including oxygenation…”
Get full text
Journal Article -
6
Patient-derived tumoroids and proteomic signatures: tools for early drug discovery
Published in Frontiers in immunology (18-04-2024)“…Onco-virotherapy is an emergent treatment for cancer based on viral vectors. The therapeutic activity is based on two different mechanisms including…”
Get full text
Journal Article -
7
Sarcomatoid Dedifferentiation in Renal Cell Carcinoma: From Novel Molecular Insights to New Clinical Opportunities
Published in Cancers (31-12-2019)“…Sarcomatoid features in renal cell carcinoma (RCC) have long been associated with dismal prognosis and poor response to therapy, while biological mechanisms…”
Get full text
Journal Article -
8
A new tumorgraft panel to accelerate precision medicine in prostate cancer
Published in Frontiers in oncology (26-05-2023)“…Despite the significant advances in the management of advanced prostate cancer (PCa), metastatic PCa is currently considered incurable. For further…”
Get full text
Journal Article -
9
Remote computer-assisted analysis of ICG fluorescence signal for evaluation of small intestinal anastomotic perfusion: a blinded, randomized, experimental trial
Published in Surgical endoscopy (01-05-2020)“…Background Indocyanine green fluorescence imaging (ICG-FI) may be used to visualize intestinal perfusion prior to anastomosis. Methods for quantification of…”
Get full text
Journal Article -
10
The phosphoinositide 3-Kinase/Akt pathway : A new target in human renal cell carcinoma therapy
Published in Cancer research (Chicago, Ill.) (15-05-2006)“…Metastatic renal cell carcinoma is resistant to current therapies. The phosphoinositide 3-kinase (PI3K)/Akt signaling cascade induces cell growth, cell…”
Get full text
Journal Article -
11
Mesenchymal-like tumor cells and myofibroblastic cancer-associated fibroblasts are associated with progression and immunotherapy response of clear-cell renal cell carcinoma
Published in Cancer research (Chicago, Ill.) (01-09-2023)“…Immune checkpoint inhibitors (ICI) represent the cornerstone for treatment of patients with metastatic clear-cell renal cell carcinoma (ccRCC). Despite a…”
Get full text
Journal Article -
12
Evaluation of Microscopic Tumour Extension in Localized Stage Non-Small-Cell Lung Cancer for Stereotactic Radiotherapy Planning
Published in Cancers (02-03-2022)“…Background: Stereotactic radiotherapy for localised stage non-small-cell lung carcinoma (NSCLC) is an alternative indication for patients who are inoperable or…”
Get full text
Journal Article -
13
An Enhancer Demethylator Phenotype Converged to Immune Dysfunction and Resistance to Immune Checkpoint Inhibitors in Clear-Cell Renal Cell Carcinomas
Published in Clinical cancer research (03-04-2023)“…Immune checkpoint inhibitors (ICI) have revolutionized the treatment of patients with clear-cell renal cell carcinomas (ccRCC). Although analyses of…”
Get full text
Journal Article -
14
Performance comparison of anti-p504s (SP116) Rabbit Monoclonal Primary Antibody vs. Monoclonal Rabbit Anti-Human AMACR clone 13H4 when duplexed with VENTANA Basal Cell Cocktail (34βE12+p63) as a diagnostic aid for prostatic adenocarcinoma using immunohistochemistry
Published in Virchows Archiv : an international journal of pathology (01-08-2021)“…Alpha-methylacyl-coenzyme A-racemase (AMACR), also known as p504s, is overexpressed in prostatic adenocarcinoma and is frequently used in combination with…”
Get full text
Journal Article -
15
Clinical impact of large genomic explorations at diagnosis in 198 pediatric solid tumors: a monocentric study aiming practical feasibility of precision oncology
Published in BMC cancer (21-10-2024)“…Faced to the growing development of collecting systematic molecular analyses in relapsed pediatric cancers to transform their targeted matched therapies, this…”
Get full text
Journal Article -
16
Establishment of a large panel of patient-derived preclinical models of human renal cell carcinoma
Published in Oncotarget (13-09-2016)“…The objective of the present work was to establish a large panel of preclinical models of human renal cell carcinoma (RCC) directly from patients, faithfully…”
Get full text
Journal Article -
17
Targeting FAK scaffold functions inhibits human renal cell carcinoma growth
Published in International journal of cancer (01-10-2015)“…Human conventional renal cell carcinoma (CCC) remains resistant to current therapies. Focal Adhesion Kinase (FAK) is upregulated in many epithelial tumors and…”
Get full text
Journal Article -
18
Peculiar Clinical Presentation of Coxsackievirus B4 Infection: Neonatal Restrictive Cardiomyopathy
Published in American journal of perinatology reports (01-04-2017)“…Restrictive cardiomyopathy in fetuses and neonates is extremely rare and has a poor outcome. Its etiology in neonates is elusive: metabolic diseases (e.g.,…”
Get full text
Journal Article -
19
Patient-Derived Lung Tumoroids—An Emerging Technology in Drug Development and Precision Medicine
Published in Biomedicines (12-07-2022)“…Synthetic 3D multicellular systems derived from patient tumors, or tumoroids, have been developed to complete the cancer research arsenal and overcome the…”
Get full text
Journal Article -
20
Vitamin D3 triggers antitumor activity through targeting hedgehog signaling in human renal cell carcinoma
Published in Carcinogenesis (New York) (01-11-2012)“…Human clear cell renal cell carcinoma (CCC) remains resistant to treatments despite the progress in targeted therapies. Several signaling pathways acting…”
Get full text
Journal Article