Search Results - "LIMAS, C. J"

Autoantibodies Against β-Adrenoceptors in Human Idiopathic Dilated Cardiomyopathy by Limas, Constantinos J, Goldenberg, Irvin F, Limas, Catherine

“…Although it is recognized that the number of cardiac β-adrenoceptors is reduced in human dilated cardiomyopathy, the mechanisms involved have not been defined…”
Get full text

Prognostic significance of soluble interleukin-2 receptor levels in patients with dilated cardiomyopathy by Limas, C. J., Hasikidis, C., Iakovou, J., Kroupis, C., Haidaroglou, A., Cokkinos, D. V.

“…Background Activation of T lymphocytes is thought to mediate myocardial dysfunction in dilated cardiomyopathy (CMP), probably through cytotoxic cytokines, but…”
Get full text

Hyperprolactinaemia in patients with heart failure: clinical and immunogenetic correlations by Limas, C. J., Kroupis, C., Haidaroglou, A., Cokkinos, D. V.

“…Background Prolactin represents a stimulatory link between the neuroendocrine and immune systems, but its involvement in the neurohumoral adaptations to heart…”
Get full text

Cardiac autoantibodies in dilated cardiomyopathy: a pathogenetic role? by Limas, C J

Get full text

Soluble interleukin-2 receptor levels in patients with dilated cardiomyopathy : correlation with disease severity and cardiac autoantibodies by LIMAS, C. J, GOLDENBERG, I. F, LIMAS, C

“…There is evidence that autoimmunity plays an important role in the initiation and progression of myocardial injury in dilated cardiomyopathy. Abnormalities of…”
Get full text

Soluble interleukin-2 receptor: is there a role in ischaemic cardiomyopathy? Authors' reply by Limas, C. J., Cokkinos, D. V.

Get full text

Beta-adrenoceptor antibodies and genetics in dilated cardiomyopathy--an overview and review by Limas, C J, Limas, C

“…Autoantibodies against the cardiac beta-adrenoceptor are present in 30-40% of patients with idiopathic dilated cardiomyopathy and can be detected using ligand…”
Get more information

Calcium uptake by cardiac sarcoplasmic reticulum in human dilated cardiomyopathy by Limas, C J, Olivari, M T, Goldenberg, I F, Levine, T B, Benditt, D G, Simon, A

“…To determine the biochemical basis of abnormal diastolic properties in human dilated cardiomyopathy calcium uptake by the sarcoplasmic reticulum in ventricular…”
Get more information

Rapid Recovery of Cardiac β-Adrenergic Receptors after Isoproterenol-Induced “Down”-Regulation by Limas, Constantinos J, Limas, Catherine

“…Desensitization of β-receptor-linked adenylate cyclase occurs after prolonged occupancy of the /8-receptors by their agonists. We have followed the development…”
Get full text

Influence of Thyroid Status on Intracellular Distribution of Cardiac Adrenoceptors by Limas, Catherine, Limas, Constantinos J

“…Previous studies have suggested that thyroid hormones influence the number of membrane-bound cardiac adrenoceptors, but their effect on the intracellular…”
Get full text

Altered intracellular adrenoceptor distribution in myocardium of spontaneously hypertensive rats by Limas, C J, Limas, C

“…The number of membrane-bound beta-adrenoceptors is reduced in the myocardium of spontaneously hypertensive rats, and this decline may account for the decreased…”
Get full text

Phorbol Ester- and Diacylglycerol-Mediated Desensitization of Cardiac β-Adrenergic Receptors by Limas, Constantinos J, Limas, Catherine

“…There are specific phorbol ester receptors on cardiac myocytes which may be identical with the calcium/phospholipid-dependent protein kinase (protein kinase…”
Get full text

HLA antigens in idiopathic dilated cardiomyopathy by Limas, C J, Limas, C

“…Disturbances of humoral and cellular immunity are common in patients with idiopathic dilated cardiomyopathy and they may contribute to the initiation and…”
Get full text

Comparative effects of hydralazine and captopril on the cardiovascular changes in spontaneously hypertensive rats by Limas, C, Westrum, B, Limas, CJ

“…Vascular changes that develop during the course of blood pressure rise in spontaneously hypertensive rats (SHRs) can be modified by antihypertensive therapy…”
Get full text

Disparate Effects of Colchicine on Thyroxine-Induced Cardiac Hypertrophy and Adrenoceptor Changes by Limas, Catherine, Limas, Constantinos J

“…Short-term (5 days) administration of L-thyroxine (0.1 mg/kg i.p. daily) to adult Sprague-Dawley rats induces a modest degree of cardiac hypertrophy (22%…”
Get full text

Influence of anti-beta-receptor antibodies on cardiac adenylate cyclase in patients with idiopathic dilated cardiomyopathy by Limas, C J, Goldenberg, I F, Limas, C

“…Autoantibodies against the cardiac beta 1-adrenoceptor are present in the sera of patients with idiopathic dilated cardiomyopathy and may modulate the…”
Get more information

Intracellular distribution of adrenoceptors in the failing human myocardium by Limas, C J, Limas, C, Goldenberg, I F

“…Although it is increasingly recognized that the density of cardiac membrane-bound beta adrenoceptors declines in heart failure, the mechanisms involved are…”
Get more information

Anti-beta-receptor antibodies in human dilated cardiomyopathy and correlation with HLA-DR antigens by Limas, Constantinos J., Limas, Catherine, Kubo, Spencer H., Olivari, Maria Teresa

“…The mechanisms responsible for the decline in the density of β-adrenoceptors in the failing myocardium have not been adequately defined. It is a possibility…”
Get full text

Prostaglandin metabolism in the kidneys of spontaneously hypertensive rats by Limas, C J, Limas, C

“…Renal prostaglandins have been implicated in the regulation of blood pressure. We have therefore compared prostaglandin metabolism in the kidneys of…”
Get full text

T-cell receptor gene polymorphisms in familial cardiomyopathy: correlation with anti-beta-receptor autoantibodies by Limas, C, Limas, C J, Boudoulas, H, Graber, H, Bair, R, Sparks, L, Wooley, C F

“…Cardiac autoantibodies have been detected in a significant proportion of patients with dilated cardiomyopathy, but their relation to the pathogenesis of the…”
Get more information