Search Results - "LIM, H. K"

Influenza A virus-induced apoptosis and virus propagation by Ampomah, Patrick B., Lim, Lina H. K.

“…Influenza A viruses (IAVs) are respiratory pathogens that cause severe morbidity and mortality worldwide. They affect cellular processes such as proliferation,…”
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Melioidosis: Clinical impact and public health threat in the tropics by Perumal Samy, Ramar, Stiles, Bradley G, Sethi, Gautam, Lim, Lina H K

“…This review briefly summarizes the geographical distribution and clinical impact of melioidosis, especially in the tropics. Burkholderia pseudomallei (a…”
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AIM2 inflammasome mediates hallmark neuropathological alterations and cognitive impairment in a mouse model of vascular dementia by Poh, Luting, Fann, David Y., Wong, Peiyan, Lim, Hong Meng, Foo, Sok Lin, Kang, Sung-Wook, Rajeev, Vismitha, Selvaraji, Sharmelee, Iyer, Vinaya Rajagopal, Parathy, Nageiswari, Khan, Mohammad Badruzzaman, Hess, David C., Jo, Dong-Gyu, Drummond, Grant R., Sobey, Christopher G., Lai, Mitchell K. P., Chen, Christopher Li-Hsian, Lim, Lina H. K., Arumugam, Thiruma V.

“…Chronic cerebral hypoperfusion is associated with vascular dementia (VaD). Cerebral hypoperfusion may initiate complex molecular and cellular inflammatory…”
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Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML by Tefferi, A, Lim, K-H, Abdel-Wahab, O, Lasho, T L, Patel, J, Patnaik, M M, Hanson, C A, Pardanani, A, Gilliland, D G, Levine, R L

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Frequent TET2 mutations in systemic mastocytosis: clinical, KITD816V and FIP1L1-PDGFRA correlates by Tefferi, A, Levine, R L, Lim, K-H, Abdel-Wahab, O, Lasho, T L, Patel, J, Finke, C M, Mullally, A, Li, C-Y, Pardanani, A, Gilliland, D G

“…TET2 (TET oncogene family member 2) is a candidate tumor suppressor gene located at chromosome 4q24, and was recently reported to be mutated in ∼14% of…”
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TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis by Tefferi, A, Pardanani, A, Lim, K-H, Abdel-Wahab, O, Lasho, T L, Patel, J, Gangat, N, Finke, C M, Schwager, S, Mullally, A, Li, C-Y, Hanson, C A, Mesa, R, Bernard, O, Delhommeau, F, Vainchenker, W, Gilliland, D G, Levine, R L

“…High-throughput DNA sequence analysis was used to screen for TET2 mutations in bone marrow-derived DNA from 239 patients with BCR-ABL -negative…”
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Breast cancer metastasis to brain results in recruitment and activation of microglia through annexin-A1/formyl peptide receptor signaling by Foo, Sok Lin, Sachaphibulkij, Karishma, Lee, Corinne L Y, Yap, Gracemary L R, Cui, Jianzhou, Arumugam, Thiruma, Lim, Lina H K

“…Despite advancements in therapies, brain metastasis in patients with triple negative subtype of breast cancer remains a therapeutic challenge. Activated…”
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Higher serum uric acid is associated with higher bone mass, lower bone turnover, and lower prevalence of vertebral fracture in healthy postmenopausal women by Ahn, S. H., Lee, S. H., Kim, B.-J., Lim, K.-H., Bae, S. J., Kim, E. H., Kim, H.-K., Choe, J. W., Koh, J.-M., Kim, G. S.

“…Summary Higher serum uric acid (UA) was associated with higher bone mass, lower bone turnover, and lower prevalence of vertebral fracture in postmenopausal…”
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Three-dimensional soft tissue changes after reduction malarplasty in female patients by Lim, H.-K., Choi, Y.-J., Choi, W.-C., Song, I.-S., Lee, U.-L.

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Inhibition of phosphatidylinositol kinase-III alpha induces or facilitates lysosome exocytosis from microglia by Mu, Shujing, Lim, Nastasia K.-H., Huang, Fude

“…Besides degradation, lysosomes can also carry molecules for secretion out of the cell, such as ATP and cytokines, during unconventional secretion…”
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Validity of self-reported weight and height: a cross-sectional study among Malaysian adolescents by Kee, C C, Lim, K H, Sumarni, M G, Teh, C H, Chan, Y Y, Nuur Hafizah, M I, Cheah, Y K, Tee, E O, Ahmad Faudzi, Y, Amal Nasir, M

“…Self-reported weight and height are commonly used in lieu of direct measurements of weight and height in large epidemiological surveys due to inevitable…”
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The Association of Insulin-dextrose Treatment with Hypoglycemia in Patients with Hyperkalemia by Crnobrnja, Ljiljana, Metlapalli, Manogna, Jiang, Cathy, Govinna, Mauli, Lim, Andy K. H.

“…Treatment of hyperkalemia with intravenous insulin-dextrose is associated with a risk of hypoglycemia. We aimed to determine the factors associated with…”
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Retinal hyperspectral imaging in the 5xFAD mouse model of Alzheimer’s disease by Lim, Jeremiah K. H., Li, Qiao-Xin, Ryan, Tim, Bedggood, Phillip, Metha, Andrew, Vingrys, Algis J., Bui, Bang V., Nguyen, Christine T. O.

“…Hyperspectral imaging of the retina has recently been posited as a potentially useful form of spectroscopy of amyloid-beta (Aβ) protein in the eyes of those…”
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Characterization of retinal function and structure in the MPTP murine model of Parkinson’s disease by Tran, Katie K. N., Wong, Vickie H. Y., Lim, Jeremiah K. H., Shahandeh, Ali, Hoang, Anh, Finkelstein, David I., Bui, Bang V., Nguyen, Christine T. O.

“…In addition to well characterized motor symptoms, visual disturbances are increasingly recognized as an early manifestation in Parkinson’s disease (PD). A…”
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Annexin-A1 promotes RIG-I-dependent signaling and apoptosis via regulation of the IRF3–IFNAR–STAT1–IFIT1 pathway in A549 lung epithelial cells by Yap, Gracemary L. R., Sachaphibulkij, Karishma, Foo, Sok Lin, Cui, Jianzhou, Fairhurst, Anna-Marie, Lim, Lina H. K.

“…Within the last century, millions of lives have been lost to the four major Influenza pandemics. These influenza pandemics were all caused by Influenza Type A…”
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Deletion of Annexin A1 in Mice Upregulates the Expression of Its Receptor, Fpr2/3, and Reactivity to the AnxA1 Mimetic Peptide in Platelets by Zharkova, Olga, Salamah, Maryam F, Babak, Maria V, Rajan, Elanchezhian, Lim, Lina H K, Andrade, Frans, Gil, Cristiane D, Oliani, Sonia M, Moraes, Leonardo A, Vaiyapuri, Sakthivel

“…Annexin A1 (ANXA1) is an endogenous protein, which plays a central function in the modulation of inflammation. While the functions of ANXA1 and its exogenous…”
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Retinal hyperspectral imaging in mouse models of Parkinson’s disease and healthy aging by Trlin, Paul, Gong, Jenny, Tran, Katie K. N., Wong, Vickie H. Y., Lee, Pei Ying, Hoang, Anh, Zhao, Da, Beauchamp, Leah C., Lim, Jeremiah K. H., Metha, Andrew, Barnham, Kevin J., Finkelstein, David I., Bui, Bang V., Bedggood, Phillip, Nguyen, Christine T. O.

“…Retinal hyperspectral imaging (HSI) is a non-invasive in vivo approach that has shown promise in Alzheimer’s disease. Parkinson’s disease is another…”
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Hardly water-soluble drug-loaded gelatin nanoparticles sustaining a slow release: preparation by novel single-step O/W/O emulsion accompanying solvent diffusion by Lee, E. J., Lim, K.-H.

“…Paclitaxel (PTX)-loaded gelatin nanoparticles (NPs) were prepared, for the first time, by novel O/W/O emulsion with a single-step emulsion process accompanying…”
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Gelatin Nanoparticle Preparation by Nanoprecipitation by Lee, E. J., Khan, S. A., Lim, K.-H.

“…This study focuses on the novel preparation of gelatin nanoparticles by nanoprecipitation. The principal parameters studied for its optimum conditions were the…”
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Inflammation in Diabetic Nephropathy by Lim, Andy K. H., Tesch, Gregory H.

“…Diabetic nephropathy is the leading cause of end-stage kidney disease worldwide but current treatments remain suboptimal. This review examines the evidence for…”
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