Search Results - "LIM, Daniel"

The Adult Ventricular-Subventricular Zone (V-SVZ) and Olfactory Bulb (OB) Neurogenesis by Lim, Daniel A, Alvarez-Buylla, Arturo

“…A large population of neural stem/precursor cells (NSCs) persists in the ventricular-subventricular zone (V-SVZ) located in the walls of the lateral brain…”
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Adult neural stem cells stake their ground by Lim, Daniel A, Alvarez-Buylla, Arturo

“…Highlights • Neural stem cells retain regional identity into adulthood. • Cerebrospinal fluid, vasculature, and neuronal activity control adult V-SVZ…”
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Universal Scherrer equation for graphene fragments by Lim, Daniel J., Marks, Nigel A., Rowles, Matthew R.

“…Graphene fragments spanning a wide range of size and shape were studied computationally using the Debye scattering equation. The calculated diffraction…”
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Limited Intervention and Moral Kindergartens by Lim, Daniel

“…Recently, William Hasker and Cheryl Chen have argued that James Sterba’s argument for the non-existence of God based on the existence of horrendous evil…”
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Long noncoding RNAs in cancer metastasis by Liu, S. John, Dang, Ha X., Lim, Daniel A., Feng, Felix Y., Maher, Christopher A.

“…Metastasis is a major contributor to cancer-associated deaths. It is characterized by a multistep process that occurs through the acquisition of molecular and…”
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Molecular Identity of Human Outer Radial Glia during Cortical Development by Pollen, Alex A., Nowakowski, Tomasz J., Chen, Jiadong, Retallack, Hanna, Sandoval-Espinosa, Carmen, Nicholas, Cory R., Shuga, Joe, Liu, Siyuan John, Oldham, Michael C., Diaz, Aaron, Lim, Daniel A., Leyrat, Anne A., West, Jay A., Kriegstein, Arnold R.

“…Radial glia, the neural stem cells of the neocortex, are located in two niches: the ventricular zone and outer subventricular zone. Although outer…”
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Mindfulness and compassion: an examination of mechanism and scalability by Lim, Daniel, Condon, Paul, DeSteno, David

“…Emerging evidence suggests that meditation engenders prosocial behaviors meant to benefit others. However, the robustness, underlying mechanisms, and potential…”
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The Long Noncoding RNA Pnky Regulates Neuronal Differentiation of Embryonic and Postnatal Neural Stem Cells by Ramos, Alexander D., Andersen, Rebecca E., Liu, Siyuan John, Nowakowski, Tomasz Jan, Hong, Sung Jun, Gertz, Caitlyn C., Salinas, Ryan D., Zarabi, Hosniya, Kriegstein, Arnold R., Lim, Daniel A.

“…While thousands of long noncoding RNAs (lncRNAs) have been identified, few lncRNAs that control neural stem cell (NSC) behavior are known. Here, we identify…”
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Forging our understanding of lncRNAs in the brain by Andersen, Rebecca E., Lim, Daniel A.

“…During both development and adulthood, the human brain expresses many thousands of long noncoding RNAs (lncRNAs), and aberrant lncRNA expression has been…”
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Potential and Pitfalls of ChatGPT and Natural-Language Artificial Intelligence Models for Diabetes Education by Sng, Gerald Gui Ren, Tung, Joshua Yi Min, Lim, Daniel Yan Zheng, Bee, Yong Mong

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Prefrontal-Subthalamic Hyperdirect Pathway Modulates Movement Inhibition in Humans by Chen, Witney, de Hemptinne, Coralie, Miller, Andrew M., Leibbrand, Michael, Little, Simon J., Lim, Daniel A., Larson, Paul S., Starr, Philip A.

“…The ability to dynamically change motor outputs, such as stopping an initiated response, is an important aspect of human behavior. A hyperdirect pathway…”
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Modulating the expression of long non‐coding RNAs for functional studies by Liu, S John, Lim, Daniel A

“…Long non‐coding RNAs (lncRNAs) have emerged as important regulators of cell biology. The mechanisms by which lncRNAs function are likely numerous, and most are…”
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Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment by Müller, Sören, Kohanbash, Gary, Liu, S John, Alvarado, Beatriz, Carrera, Diego, Bhaduri, Aparna, Watchmaker, Payal B, Yagnik, Garima, Di Lullo, Elizabeth, Malatesta, Martina, Amankulor, Nduka M, Kriegstein, Arnold R, Lim, Daniel A, Aghi, Manish, Okada, Hideho, Diaz, Aaron

“…Tumor-associated macrophages (TAMs) are abundant in gliomas and immunosuppressive TAMs are a barrier to emerging immunotherapies. It is unknown to what extent…”
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Spatiotemporal gene expression trajectories reveal developmental hierarchies of the human cortex by Nowakowski, Tomasz J., Bhaduri, Aparna, Pollen, Alex A., Alvarado, Beatriz, Mostajo-Radji, Mohammed A., Di Lullo, Elizabeth, Haeussler, Maximilian, Sandoval-Espinosa, Carmen, Liu, Siyuan John, Velmeshev, Dmitry, Ounadjela, Johain Ryad, Shuga, Joe, Wang, Xiaohui, Lim, Daniel A., West, Jay A., Leyrat, Anne A., Kent, W. James, Kriegstein, Arnold R.

“…Systematic analyses of spatiotemporal gene expression trajectories during organogenesis have been challenging because diverse cell types at different stages of…”
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CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells by Liu, S. John, Horlbeck, Max A., Cho, Seung Woo, Birk, Harjus S., Malatesta, Martina, He, Daniel, Attenello, Frank J., Villalta, Jacqueline E., Cho, Min Y., Chen, Yuwen, Mandegar, Mohammad A., Olvera, Michael P., Gilbert, Luke A., Conklin, Bruce R., Chang, Howard Y., Weissman, Jonathan S., Lim, Daniel A.

“…The human genome produces thousands of long noncoding RNAs (lncRNAs)-transcripts >200 nucleotides long that do not encode proteins. Although critical roles in…”
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Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element by Cho, Seung Woo, Xu, Jin, Sun, Ruping, Mumbach, Maxwell R., Carter, Ava C., Chen, Y. Grace, Yost, Kathryn E., Kim, Jeewon, He, Jing, Nevins, Stephanie A., Chin, Suet-Feung, Caldas, Carlos, Liu, S. John, Horlbeck, Max A., Lim, Daniel A., Weissman, Jonathan S., Curtis, Christina, Chang, Howard Y.

“…Noncoding mutations in cancer genomes are frequent but challenging to interpret. PVT1 encodes an oncogenic lncRNA, but recurrent translocations and deletions…”
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A single-cell atlas of the normal and malformed human brain vasculature by Winkler, Ethan A, Kim, Chang N, Ross, Jayden M, Garcia, Joseph H, Gil, Eugene, Oh, Irene, Chen, Lindsay Q, Wu, David, Catapano, Joshua S, Raygor, Kunal, Narsinh, Kazim, Kim, Helen, Weinsheimer, Shantel, Cooke, Daniel L, Walcott, Brian P, Lawton, Michael T, Gupta, Nalin, Zlokovic, Berislav V, Chang, Edward F, Abla, Adib A, Lim, Daniel A, Nowakowski, Tomasz J

“…Cerebrovascular diseases are a leading cause of death and neurologic disability. Further understanding of disease mechanisms and therapeutic strategies…”
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CONICS integrates scRNA-seq with DNA sequencing to map gene expression to tumor sub-clones by Müller, Sören, Cho, Ara, Liu, Siyuan J, Lim, Daniel A, Diaz, Aaron

“…Abstract Motivation Single-cell RNA-sequencing (scRNA-seq) has enabled studies of tissue composition at unprecedented resolution. However, the application of…”
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miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells by Silber, Joachim, Lim, Daniel A, Petritsch, Claudia, Persson, Anders I, Maunakea, Alika K, Yu, Mamie, Vandenberg, Scott R, Ginzinger, David G, James, C David, Costello, Joseph F, Bergers, Gabriele, Weiss, William A, Alvarez-Buylla, Arturo, Hodgson, J Graeme

“…Glioblastoma multiforme (GBM) is an invariably fatal central nervous system tumor despite treatment with surgery, radiation, and chemotherapy. Further insights…”
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Acceptance of Tele-Rehabilitation by Stroke Patients: Perceived Barriers and Facilitators by Tyagi, Shilpa, Lim, Daniel S.Y., Ho, Wilbert H.H., Koh, Yun Qing, Cai, Vincent, Koh, Gerald C.H., Legido-Quigley, Helena

“…To explore the perceived barriers and facilitators of tele-rehabilitation (TR) by stroke patients, caregivers and rehabilitation therapists in an Asian…”
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