Search Results - "LIM, Andrew S. P"

Modification of the relationship of the apolipoprotein E ε4 allele to the risk of Alzheimer disease and neurofibrillary tangle density by sleep by Lim, Andrew S P, Yu, Lei, Kowgier, Matthew, Schneider, Julie A, Buchman, Aron S, Bennett, David A

“…The apolipoprotein E (APOE [GenBank, 348; OMIM, 107741]) ε4 allele is a common and well-established genetic risk factor for Alzheimer disease (AD). Sleep…”
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Association of accelerometer-derived sleep measures with lifetime psychiatric diagnoses: A cross-sectional study of 89,205 participants from the UK Biobank by Wainberg, Michael, Jones, Samuel E, Beaupre, Lindsay Melhuish, Hill, Sean L, Felsky, Daniel, Rivas, Manuel A, Lim, Andrew S P, Ollila, Hanna M, Tripathy, Shreejoy J

“…Sleep problems are both symptoms of and modifiable risk factors for many psychiatric disorders. Wrist-worn accelerometers enable objective measurement of sleep…”
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Correlates of Person-Specific Rates of Change in Sensor-Derived Physical Activity Metrics of Daily Living in the Rush Memory and Aging Project by Buchman, Aron S, Wang, Tianhao, Oveisgharan, Shahram, Zammit, Andrea R, Yu, Lei, Li, Peng, Hu, Kun, Hausdorff, Jeffrey M, Lim, Andrew S P, Bennett, David A

“…This study characterized person-specific rates of change of total daily physical activity (TDPA) and identified correlates of this change. TDPA metrics were…”
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Seasonal plasticity of cognition and related biological measures in adults with and without Alzheimer disease: Analysis of multiple cohorts by Lim, Andrew S P, Gaiteri, Chris, Yu, Lei, Sohail, Shahmir, Swardfager, Walter, Tasaki, Shinya, Schneider, Julie A, Paquet, Claire, Stuss, Donald T, Masellis, Mario, Black, Sandra E, Hugon, Jacques, Buchman, Aron S, Barnes, Lisa L, Bennett, David A, De Jager, Philip L

“…There are few data concerning the association between season and cognition and its neurobiological correlates in older persons-effects with important…”
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Retraction: 24-Hour Rhythms of DNA Methylation and Their Relation with Rhythms of RNA Expression in the Human Dorsolateral Prefrontal Cortex by Lim, Andrew S. P, Srivastava, Gyan P, Yu, Lei, Chibnik, Lori B, Xu, Jishu, Buchman, Aron S, Schneider, Julie A, Myers, Amanda J, Bennett, David A, De Jager, Philip L

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Sleep Fragmentation and the Risk of Incident Alzheimer's Disease and Cognitive Decline in Older Persons by Lim, Andrew S P, Kowgier, Matthew, Yu, Lei, Buchman, Aron S, Bennett, David A

“…Cross-sectional studies suggest that sleep fragmentation is associated with cognitive performance in older adults. We tested the hypothesis that sleep…”
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A common polymorphism near PER1 and the timing of human behavioral rhythms by Lim, Andrew S. P., Chang, Anne-Marie, Shulman, Joshua M., Raj, Towfique, Chibnik, Lori B., Cain, Sean W., Rothamel, Katherine, Benoist, Christophe, Myers, Amanda J., Czeisler, Charles A., Buchman, Aron S., Bennett, David A., Duffy, Jeanne F., Saper, Clifford B., De Jager, Philip L.

“…Objective: Circadian rhythms influence the timing of behavior, neurological diseases, and even death. Rare mutations in homologs of evolutionarily conserved…”
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Sleep is related to neuron numbers in the ventrolateral preoptic/intermediate nucleus in older adults with and without Alzheimer's disease by LIM, Andrew S. P, ELLISON, Brian A, WANG, Joshua L, LEI YU, SCHNEIDER, Julie A, BUCHMAN, Aron S, BENNETT, David A, SAPER, Clifford B

“…Fragmented sleep is a common and troubling symptom in ageing and Alzheimer's disease; however, its neurobiological basis in many patients is unknown. In…”
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Sleep fragmentation and Parkinson's disease pathology in older adults without Parkinson's disease by Sohail, Shahmir, Yu, Lei, Schneider, Julie A., Bennett, David A., Buchman, Aron S., Lim, Andrew S. P.

“…ABSTRACT Introduction Patients with Parkinson's disease (PD) frequently experience disrupted sleep, and several sleep abnormalities are associated with an…”
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Irregular 24-hour activity rhythms and the metabolic syndrome in older adults by Sohail, Shahmir, Yu, Lei, Bennett, David A, Buchman, Aron S, Lim, Andrew S P

“…Circadian rhythms - near 24 h intrinsic biological rhythms - modulate many aspects of human physiology and hence disruption of circadian rhythms may have an…”
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Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer’s disease by Lim, Andrew S. P., Klein, Hans-Ulrich, Yu, Lei, Chibnik, Lori B., Ali, Sanam, Xu, Jishu, Bennett, David A., De Jager, Philip L.

“…Circadian and seasonal rhythms are seen in many species, modulate several aspects of human physiology, including brain functions such as mood and cognition,…”
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Circadian disturbances in Alzheimer's disease progression: a prospective observational cohort study of community-based older adults by Li, Peng, Gao, Lei, Gaba, Arlen, Yu, Lei, Cui, Longchang, Fan, Wenqing, Lim, Andrew S P, Bennett, David A, Buchman, Aron S, Hu, Kun

“…Circadian disturbances are commonly seen in people with Alzheimer's disease and have been reported in individuals without symptoms of dementia but with…”
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24-hour rhythms of DNA methylation and their relation with rhythms of RNA expression in the human dorsolateral prefrontal cortex by Lim, Andrew S P, Srivastava, Gyan P, Yu, Lei, Chibnik, Lori B, Xu, Jishu, Buchman, Aron S, Schneider, Julie A, Myers, Amanda J, Bennett, David A, De Jager, Philip L

“…Circadian rhythms modulate the biology of many human tissues, including brain tissues, and are driven by a near 24-hour transcriptional feedback loop. These…”
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Locus coeruleus neuron density and parkinsonism in older adults without Parkinson's disease by Buchman, Aron S., Nag, Sukriti, Shulman, Joshua M., Lim, Andrew S.P., VanderHorst, Veronique G.J.M., Leurgans, Sue E., Schneider, Julie A., Bennett, David A.

“…Previous work has showed that nigral neuron density is related to the severity of parkinsonism proximate to death in older persons without a clinical diagnosis…”
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Sex Difference in Daily Rhythms of Clock Gene Expression in the Aged Human Cerebral Cortex by Lim, Andrew S.P., Myers, Amanda J., Yu, Lei, Buchman, Aron S., Duffy, Jeanne F., De Jager, Philip L., Bennett, David A.

“…Studies using self-report and physiological markers of circadian rhythmicity have demonstrated sex differences in a number of circadian attributes including…”
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Fragmentation of Rest/Activity Patterns in Community-Based Elderly Individuals Predicts Incident Heart Failure by Gao, Lei, Lim, Andrew S P, Wong, Patricia M, Gaba, Arlen, Cui, Longchang, Yu, Lei, Buchman, Aron S, Bennett, David A, Hu, Kun, Li, Peng

“…Heart failure has previously been linked to sleep disorders that are often associated with frequent disturbances to human rest/activity patterns. We tested…”
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Disrupted Rest-Activity Rhythms and Cerebral Small Vessel Disease Pathology in Older Adults by Sommer, Rosa, Yu, Lei, Schneider, Julie A., Bennett, David A., Buchman, Aron S., Lim, Andrew S.P.

“…The pathogenesis of cerebral small vessel disease remains incompletely understood. The relationship between circadian rhythm disturbances and histopathologic…”
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Regional Neocortical Gray Matter Structure and Sleep Fragmentation in Older Adults by Lim, Andrew S P, Fleischman, Debra A, Dawe, Robert J, Yu, Lei, Arfanakis, Konstantinos, Buchman, Aron S, Bennett, David A

“…To test the hypothesis that greater sleep fragmentation is associated with regionally decreased cortical gray matter volume in older community-dwelling adults…”
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Circadian alterations during early stages of Alzheimer's disease are associated with aberrant cycles of DNA methylation in BMAL1 by Cronin, Peter, McCarthy, Michael J, Lim, Andrew S.P, Salmon, David P, Galasko, Douglas, Masliah, Eliezer, De Jager, Philip L, Bennett, David A, Desplats, Paula

“…Abstract Introduction Circadian alterations are prevalent in Alzheimer's disease (AD) and may contribute to cognitive impairment, behavioral symptoms, and…”
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Fragmentation of rest periods, astrocyte activation, and cognitive decline in older adults with and without Alzheimer's disease by Wu, Rebecca, Tripathy, Shreejoy, Menon, Vilas, Yu, Lei, Buchman, Aron S., Bennett, David A., De Jager, Philip L., Lim, Andrew S. P.

“…Introduction Sleep disruption is associated with astrocyte activation and impaired cognition in model organisms. However, the relationship among sleep,…”
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