Search Results - "LIHUA BAO"

Complement Factor H Deficiency Accelerates Development of Lupus Nephritis by LIHUA BAO, HAAS, Mark, QUIGG, Richard J

“…Complement factor H (CfH) is a key regulator of the alternative pathway, and its presence on mouse platelets and podocytes allows the processing of immune…”
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Resveratrol inhibits β-amyloid-induced neuronal apoptosis through regulation of SIRT1-ROCK1 signaling pathway by Feng, Xiaowen, Liang, Nan, Zhu, Dexiao, Gao, Qing, Peng, Lei, Dong, Haiman, Yue, Qingwei, Liu, Haili, Bao, Lihua, Zhang, Jing, Hao, Jing, Gao, Yingmao, Yu, Xuejie, Sun, Jinhao

“…Alzheimer's disease (AD) is characterized by the accumulation of β-amyloid peptide (Aβ) and loss of neurons. Recently, a growing body of evidences have…”
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Renal FcRn Reclaims Albumin but Facilitates Elimination of IgG by SARAV, Menaka, YING WANG, HACK, Bradley K, CHANG, Anthony, JENSEN, Mark, LIHUA BAO, QUIGG, Richard J

“…The widely distributed neonatal Fc receptor (FcRn) contributes to maintaining serum levels of albumin and IgG in adults. In the kidney, FcRn is expressed on…”
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Complement in Lupus Nephritis: New Perspectives by Bao, Lihua, Cunningham, Patrick N., Quigg, Richard J.

“…Background: Systemic lupus erythematosus (SLE) is an autoimmune disorder caused by loss of tolerance to self-antigens, the production of autoantibodies and…”
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Distinct roles for C3a and C5a in complement-induced tubulointerstitial injury by Bao, Lihua, Wang, Ying, Haas, Mark, Quigg, Richard J.

“…To prevent injury to host tissues, complement activation is regulated by a number of plasma and membrane-associated proteins, most of which limit C3 and C5…”
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18F-FDG PET/CT and PET for evaluation of pathological response to neoadjuvant chemotherapy in breast cancer: a meta-analysis by Cheng, Xu, Li, Yongjun, Liu, Biao, Xu, Zhaoqiang, Bao, Lihua, Wang, Jie

“…Neoadjuvant chemotherapy is increasingly the treatment for patients with inoperable breast cancer. Considering the side-effects of chemotherapy, there is a…”
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Loss of CD11b exacerbates murine complement-mediated tubulointerstitial nephritis by Chaves, Lee Daniel, Bao, Lihua, Wang, Ying, Chang, Anthony, Haas, Mark, Quigg, Richard John

“…Acute complement activation occurs in the tubulointerstitium (TI) of kidneys transplanted from Crry(-/-)C3(-/-) mice into complement-sufficient wildtype mice,…”
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TNF causes changes in glomerular endothelial permeability and morphology through a Rho and myosin light chain kinase‐dependent mechanism by Xu, Chang, Wu, Xiaoyan, Hack, Bradley K., Bao, Lihua, Cunningham, Patrick N.

“…A key function of the endothelium is to serve as a regulated barrier between tissue compartments. We have previously shown that tumor necrosis factor (TNF)…”
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Signaling through Up-Regulated C3a Receptor Is Key to the Development of Experimental Lupus Nephritis by Bao, Lihua, Osawe, Iyabo, Haas, Mark, Quigg, Richard J

“…Signaling of the C3a anaphylatoxin through its G protein-coupled receptor, C3aR, is relevant in a variety of inflammatory diseases, but its role in lupus…”
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Unrestricted C3 activation occurs in crry-deficient kidneys and rapidly leads to chronic renal failure by LIHUA BAO, YING WANG, CHANG, Anthony, MINTO, Andrew W, JIAN ZHOU, HONG KANG, HAAS, Mark, QUIGG, Richard J

“…Deficiency of the C3 convertase regulator Crry is embryonic lethal in mice unless C3 also is absent. For evaluation of the effect of local kidney Crry…”
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Comparison of 18F-FDG PET/CT with bone scintigraphy for detection of bone metastasis: a meta-analysis by Cheng, Xu, Li, Yongjun, Xu, Zhaoqiang, Bao, Lihua, Li, Dianfu, Wang, Jie

“…The skeleton is one of the favorable sites for the metastasis of almost all human malignant neoplasms. An accurate diagnosis of bone metastasis is crucial for…”
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Administration of a soluble recombinant complement C3 inhibitor protects against renal disease in MRL/lpr mice by BAD, Lihua, HAAS, Mark, KRAUS, Damian M, HACK, Bradley K, RAKSTANG, Jonathan K, HOLERS, V. Michael, QUIGG, Richard J

“…Complement receptor 1-related gene/protein y (Crry) in rodents is a potent membrane complement regulator that inhibits complement C3 activation by both…”
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Decay-accelerating factor but not CD59 limits experimental immune-complex glomerulonephritis by Bao, Lihua, Haas, Mark, Minto, Andrew W, Quigg, Richard J

“…The complex balance between the pro-activating and regulatory influences of the complement system can affect the pathogenesis of immune complex-mediated…”
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Inhibiting the complement system does not reduce injury in renal ischemia reperfusion by PARK, Pierce, HAAS, Mark, CUNNINGHAM, Patrick N, ALEXANDER, Jessy J, LIHUA BAO, GUTHRIDGE, Joel M, KRAUS, Damian M, HOLERS, V. Michael, QUIGG, Richard J

“…The complex pathogenesis of ischemia reperfusion injury (IRI) includes endothelial expression of adhesion molecules, leukocyte recruitment and activation,…”
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Dopaminergic differentiation of grafted GFP transgenic neuroepithelial stem cells in the brain of a rat model of Parkinson's disease by Sun, Jinhao, Gao, Qing, Miller, Katherine, Wang, Xian, Wang, Jiazeng, Liu, Wenjing, Bao, Lihua, Zhang, Jing, Zhang, Liping, Poon, W.S., Gao, Yingmao

“…Neuroepithelial stem cells (NEPs) possess multipotent potential for self-renewal and neuronal differentiation. Using green fluorescent protein (GFP) positive…”
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Prominent renal expression of a murine leukemia retrovirus in experimental systemic lupus erythematosus by ALEXANDER, Jessy J, SAXENA, Amit K, LIHUA BAO, JACOB, Alexander, HAAS, Mark, QUIGG, Richard J

“…A role for retroviruses in human systemic lupus erythematosus (SLE) and in mouse lupus models such as the New Zealand Black and White mice (NZB/W) strain has…”
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Decay-accelerating factor expression in the rat kidney is restricted to the apical surface of podocytes by Bao, Lihua, Spiller, O. Brad, St. John, Patricia L., Haas, Mark, Hack, Bradley K., Ren, Guohui, Cunningham, Patrick N., Doshi, Mona, Abrahamson, Dale R., Morgan, B. Paul, Quigg, Richard J.

“…Decay-accelerating factor expression in the rat kidney is restricted to the apical surface of podocytes. Decay-accelerating factor (DAF) has inhibitory…”
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Bone damage in osteoporotic fractures by Lin, H, Bao, Lihua

“…Osteoporotic fracture is fundamentally different from traumatic fracture. It is a pathological fracture based on the skeletal system in the state of…”
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Metabolic disposition of [14C]‐abivertinib, an epidermal growth factor receptor tyrosine kinase inhibitor: Role of glutathione conjugation by Wang, Lu, Guo, Lian, Wang, Yixiang, Guo, Renhua, Xu, Zhaoqiang, Gao, Zhengzhen, Xie, Lijun, Chen, Juan, Chen, Ying, Liu, Yun, Zhang, Hongwen, Bao, Lihua, Xu, Wanhong, Zhu, Mingshe, Shao, Feng, Shu, Yongqian

“…Aims To determine the absorption, distribution, metabolism and excretion of abivertinib, a third‐generation epidermal growth factor receptor tyrosine kinase…”
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Evaluation of frailty status among older people living in urban communities by Edmonton Frail Scale in Wuhu, China: a cross-sectional study by Yang, Liu, Jiang, Yumin, Xu, Shuxiu, Bao, Lihua, Parker, Deborah, Xu, Xiaoyue, Li, Jinzhi

“…Background: Few studies have explored the factors that are associated with frailty among older people. Objective: To investigate the frailty status and examine…”
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