Search Results - "LIGHT, PETER E."

Non-invasive continuous-time glucose monitoring system using a chipless printable sensor based on split ring microwave resonators by Baghelani, Masoud, Abbasi, Zahra, Daneshmand, Mojgan, Light, Peter E.

“…This paper reports a highly sensitive, non-invasive sensor for real-time glucose monitoring from interstitial fluid. The structure is comprised of a chip-less…”
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Cardiac mechanisms of the beneficial effects of SGLT2 inhibitors in heart failure: Evidence for potential off-target effects by Dyck, Jason R.B., Sossalla, Samuel, Hamdani, Nazha, Coronel, Ruben, Weber, Nina C., Light, Peter E., Zuurbier, Coert J.

“…Sodium glucose cotransporter 2 inhibitors (SGLT2i) constitute a promising drug treatment for heart failure patients with either preserved or reduced ejection…”
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Cardiac Late Sodium Channel Current Is a Molecular Target for the Sodium/Glucose Cotransporter 2 Inhibitor Empagliflozin by Philippaert, Koenraad, Kalyaanamoorthy, Subha, Fatehi, Mohammad, Long, Wentong, Soni, Shubham, Byrne, Nikole J., Barr, Amy, Singh, Jyoti, Wong, Jordan, Palechuk, Taylor, Schneider, Chloe, Darwesh, Ahmed M., Maayah, Zaid H., Seubert, John M., Barakat, Khaled, Dyck, Jason R.B., Light, Peter E.

“…SGLT2 (sodium/glucose cotransporter 2) inhibitors exert robust cardioprotective effects against heart failure in patients with diabetes, and there is intense…”
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Human islets contain a subpopulation of glucagon-like peptide-1 secreting α cells that is increased in type 2 diabetes by Campbell, Scott A., Golec, Dominic P., Hubert, Matt, Johnson, Janyne, Salamon, Nicole, Barr, Amy, MacDonald, Patrick E., Philippaert, Koenraad, Light, Peter E.

“…Our study shows that glucagon-like peptide-1 (GLP-1) is secreted within human islets and may play an unexpectedly important paracrine role in islet physiology…”
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Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility by NAGENDRAN, Jayan, ARCHER, Stephen L, LIGHT, Peter E, DYCK, Jason R. B, MICHELAKIS, Evangelos D, SOLIMAN, Daniel, GURTU, Vikram, MOUDGIL, Rohit, HAROMY, Alois, AUBIN, Chantal St, WEBSTER, Linda, REBEYKA, Ivan M, ROSS, David B

“…Sildenafil was recently approved for the treatment of pulmonary arterial hypertension. The beneficial effects of phosphodiesterase type 5 (PDE5) inhibitors in…”
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Resveratrol Prevents the Prohypertrophic Effects of Oxidative Stress on LKB1 by DOLINSKY, Vernon W, CHAN, Anita Y. M, ROBILLARD FRAYNE, Isabelle, LIGHT, Peter E, DES ROSIERS, Christine, DYCK, Jason R. B

“…Master regulators of protein synthesis such as mammalian target of rapamycin (mTOR) and p70S6 kinase contribute to left ventricular hypertrophy. These…”
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Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis by Ondrusova, Katarina, Fatehi, Mohammad, Barr, Amy, Czarnecka, Zofia, Long, Wentong, Suzuki, Kunimasa, Campbell, Scott, Philippaert, Koenraad, Hubert, Matthew, Tredget, Edward, Kwan, Peter, Touret, Nicolas, Wabitsch, Martin, Lee, Kevin Y., Light, Peter E.

“…Subcutaneous white adipose tissue (scWAT) is the major fat depot in humans and is a central player in regulating whole body metabolism. Skin exposure to UV…”
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Selective enhancement of cardiomyocyte efficiency results in a pernicious heart condition by Groenendyk, Jody, Wang, Qian, Wagg, Cory, Lee, Dukgyu, Robinson, Alison, Barr, Amy, Light, Peter E, Lopaschuk, Gary D, Agellon, Luis B, Michalak, Marek

“…Transgenic mice with selective induction of calreticulin transgene expression in cardiomyocytes (Cardiac.sup.CRT+) were analyzed. Cardiac.sup.CRT+…”
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Resveratrol Inhibits Cardiac Hypertrophy via AMP-activated Protein Kinase and Akt by Chan, Anita Y.M., Dolinsky, Vernon W., Soltys, Carrie-Lynn M., Viollet, Benoit, Baksh, Shairaz, Light, Peter E., Dyck, Jason R.B.

“…Whereas studies involving animal models of cardiovascular disease demonstrated that resveratrol is able to inhibit hypertrophic growth, the mechanisms involved…”
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Direct Binding between Pre-S1 and TRP-like Domains in TRPP Channels Mediates Gating and Functional Regulation by PIP2 by Zheng, Wang, Cai, Ruiqi, Hofmann, Laura, Nesin, Vasyl, Hu, Qiaolin, Long, Wentong, Fatehi, Mohammad, Liu, Xiong, Hussein, Shaimaa, Kong, Tim, Li, Jingru, Light, Peter E., Tang, Jingfeng, Flockerzi, Veit, Tsiokas, Leonidas, Chen, Xing-Zhen

“…Transient receptor potential (TRP) channels are regulated by diverse stimuli comprising thermal, chemical, and mechanical modalities. They are also commonly…”
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Myocardial ATGL Overexpression Decreases the Reliance on Fatty Acid Oxidation and Protects against Pressure Overload-Induced Cardiac Dysfunction by Kienesberger, Petra C., Pulinilkunnil, Thomas, Sung, Miranda M. Y., Nagendran, Jeevan, Haemmerle, Guenter, Kershaw, Erin E., Young, Martin E., Light, Peter E., Oudit, Gavin Y., Zechner, Rudolf, Dyck, Jason R. B.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Decoding the effects of SGLT2 inhibitors on cardiac arrhythmias in heart failure by Light, Peter E

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Coexpression of the Type 2 Diabetes Susceptibility Gene Variants KCNJ11 E23K and ABCC8 S1369A Alter the ATP and Sulfonylurea Sensitivities of the ATP-Sensitive K+ Channel by Hamming, Kevin S C, Soliman, Daniel, Matemisz, Laura C, Niazi, Omid, Lang, Yiqiao, Gloyn, Anna L, Light, Peter E

“…Coexpression of the Type 2 Diabetes Susceptibility Gene Variants KCNJ11 E23K and ABCC8 S1369A Alter the ATP and Sulfonylurea Sensitivities of the ATP-Sensitive…”
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Islet Cholesterol Accumulation Due to Loss of ABCA1 Leads to Impaired Exocytosis of Insulin Granules by KRUIT, Janine K, WIJESEKARA, Nadeeja, JOHNSON, James D, LIGHT, Peter E, MARSH, Brad J, MACDONALD, Patrick E, BRUCE VERCHERE, C, HAYDEN, Michael R, MANNING FOX, Jocelyn E, DAI, Xiao-Qing, BRUNHAM, Liam R, SEARLE, Gavin J, MORGAN, Garry P, COSTIN, Adam J, RENMEI TANG, BHATTACHARJEE, Alpana

“…The ATP-binding cassette transporter A1 (ABCA1) is essential for normal insulin secretion from β-cells. The aim of this study was to elucidate the mechanisms…”
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The Multiple Actions of GLP-1 on the Process of Glucose-Stimulated Insulin Secretion by MacDonald, Patrick E, El-Kholy, Wasim, Riedel, Michael J, Salapatek, Anne Marie F, Light, Peter E, Wheeler, Michael B

“…The Multiple Actions of GLP-1 on the Process of Glucose-Stimulated Insulin Secretion Patrick E. MacDonald 1 , Wasim El-kholy 1 , Michael J. Riedel 2 , Anne…”
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Intracellular long-chain acyl CoAs activate TRPV1 channels by Yu, Yi, Carter, Chris R J, Youssef, Nermeen, Dyck, Jason R B, Light, Peter E

“…TRPV1 channels are an important class of membrane proteins that play an integral role in the regulation of intracellular cations such as calcium in many…”
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Mixed SYGnals in potassium channels: a mechanism for alternative ion conduction in human Kir3.2 channel mutations by Light, Peter E.

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In–human testing of a non-invasive continuous low–energy microwave glucose sensor with advanced machine learning capabilities by Kazemi, Nazli, Abdolrazzaghi, Mohammad, Light, Peter E., Musilek, Petr

“…Continuous glucose monitoring schemes that avoid finger pricking are of utmost importance to enhance the comfort and lifestyle of diabetic patients. To this…”
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Noninvasive Glucose Sensing in Aqueous Solutions Using an Active Split-Ring Resonator by Abdolrazzaghi, Mohammad, Katchinskiy, Nir, Elezzabi, Abdulhakem Y., Light, Peter E., Daneshmand, Mojgan

“…It is shown here that microwave sensors can be used to monitor glucose in serum concentration with minimum detectable as well as resolution of 1…”
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Characterization of a novel multifunctional resveratrol derivative for the treatment of atrial fibrillation by Baczko, Istvan, Liknes, David, Yang, Wei, Hamming, Kevin C, Searle, Gavin, Jaeger, Kristian, Husti, Zoltan, Juhasz, Viktor, Klausz, Gergely, Pap, Robert, Saghy, Laszlo, Varro, Andras, Dolinsky, Vernon, Wang, Shaohua, Rauniyar, Vivek, Hall, Dennis, Dyck, Jason RB, Light, Peter E

“…Background and Purpose Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with an increased risk for stroke, heart failure and…”
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