Search Results - "LIGGINS, R. T"

Polyether–polyester diblock copolymers for the preparation of paclitaxel loaded polymeric micelle formulations by Liggins, R.T., Burt, H.M.

“…A number of hypersensitivity reactions have been attributed to the presence of Cremophor ® EL in the current formulation for paclitaxel. This has led to the…”
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Development and in vitro characterization of paclitaxel and docetaxel loaded into hydrophobically derivatized hyperbranched polyglycerols by Mugabe, C., Liggins, R.T., Guan, D., Manisali, I., Chafeeva, I., Brooks, D.E., Heller, M., Jackson, J.K., Burt, H.M.

“…In this study we report the development and in vitro characterization of paclitaxel (PTX) and docetaxel (DTX) loaded into…”
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Paclitaxel loaded poly(L-lactic acid) microspheres for the prevention of intraperitoneal carcinomatosis after a surgical repair and tumor cell spill by LIGGINS, R. T, D'AMOURS, S, DEMETRICK, J. S, MACHAN, L. S, BURT, H. M

“…A controlled release delivery system for paclitaxel was developed using poly(L-lactic acid) to provide local delivery to the peritoneal cavity. Microspheres…”
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Solid-state characterization of paclitaxel by Liggins, R T, Hunter, W L, Burt, H M

“…The purpose of this work was to characterize the solid-state properties of anhydrous paclitaxel and paclitaxel dihydrate. Paclitaxel I (anhydrous) was…”
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Intra-articular treatment of arthritis with microsphere formulations of paclitaxel: biocompatibility and efficacy determinations in rabbits by Liggins, R T, Cruz, T, Min, W, Liang, L, Hunter, W L, Burt, H M

“…To assess the biocompatibility of controlled release microspheres prepared from different polymeric biomaterials in various size ranges in rabbit synovial…”
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Controlled delivery of taxol from microspheres composed of a blend of ethylene-vinyl acetate copolymer and poly ( d,l-lactic acid) by Burt, Helen M., Jackson, John K., Bains, Sarvjeet K., Liggins, Richard T., Oktaba, Ann Marie C., Arsenault, A.Larry, Hunter, William L.

“…‘Large’ (30–100 μm) and ‘small’ (10–30 μm) size range taxol-loaded microspheres composed of a blend of biodegradable poly ( d,l-lactic acid) (PLA) polymer and…”
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Paclitaxel loaded poly( l-lactic acid) (PLLA) microspheres : II. The effect of processing parameters on microsphere morphology and drug release kinetics by Liggins, Richard T, Burt, Helen M

“…The kinetics of solvent removal in microsphere preparation and their effect on the morphology and release characteristics of paclitaxel-loaded PLLA…”
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Paclitaxel loaded poly(L-lactic acid) microspheres: properties of microspheres made with low molecular weight polymers by Liggins, Richard T., Burt, Helen M.

“…Microspheres were prepared from poly(L-lactic acid) polymers having molecular weights between 500 and 50k g/mol. The polymers were synthesized using two…”
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The development of a novel intraperitoneal tumor-seeding prophylactic by Demetrick, Jeffrey S., Liggins, Richard T., Machan, Lindsay, Davis, Noelle L., Burt, Helen M., Hunter, William L.

“…Peritoneal tumor dissemination and implantation is a complication of both open and laparoscopic oncologic surgery. This study evaluates the efficacy of…”
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Polyether-polyester diblock copolymers for the preparation of paclitaxel loaded polymeric micelle formulations: Block copolymer micelles for drug delivery by LIGGINS, R. T, BURT, H. M

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Paclitaxel-loaded poly( l-lactic acid) microspheres 3: blending low and high molecular weight polymers to control morphology and drug release by Liggins, Richard T., Burt, Helen M.

“…Microspheres were prepared from paclitaxel and binary polymer blends incorporating 1, 3, 40k and 100k g/mol PLLA. Thermal analysis was performed by DSC and in…”
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