Search Results - "LIEBENBERG, Ellen"

Innervation of pathologies in the lumbar vertebral end plate and intervertebral disc by Fields, Aaron J., PhD, Liebenberg, Ellen C., BS, Lotz, Jeffrey C., PhD

“…Abstract Background context Magnetic resonance imaging (MRI) has limited diagnostic value for chronic low back pain because of the unclear relationship between…”
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Cartilage Endplate Thickness Variation Measured by Ultrashort Echo-Time MRI Is Associated With Adjacent Disc Degeneration by Berg-Johansen, Britta, Han, Misung, Fields, Aaron J., Liebenberg, Ellen C., Lim, Brandon J., Larson, Peder EZ, Gunduz-Demir, Cigdem, Kazakia, Galateia J., Krug, Roland, Lotz, Jeffrey C.

“…A magnetic resonance imaging study of human cadaver spines. To investigate associations between cartilage endplate (CEP) thickness and disc degeneration…”
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Structure‐function relationships at the human spinal disc‐vertebra interface by Berg‐Johansen, Britta, Fields, Aaron J., Liebenberg, Ellen C., Li, Alfred, Lotz, Jeffrey C.

“…ABSTRACT Damage at the intervertebral disc‐vertebra interface associates with back pain and disc herniation. However, the structural and biomechanical…”
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Alterations in intervertebral disc composition, matrix homeostasis and biomechanical behavior in the UCD-T2DM rat model of type 2 diabetes by Fields, Aaron J., Berg-Johansen, Britta, Metz, Lionel N., Miller, Stephanie, La, Brandan, Liebenberg, Ellen C., Coughlin, Dezba G., Graham, James L., Stanhope, Kimber L., Havel, Peter J., Lotz, Jeffrey C.

“…ABSTRACT Type 2 diabetes (T2D) adversely affects many tissues, and the greater incidence of discogenic low back pain among diabetic patients suggests that the…”
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ISSLS Prize Winner : Repeated Disc Injury Causes Persistent Inflammation by ULRICH, Jill A, LIEBENBERG, Ellen C, THUILLIER, Daniel U, LOTZ, Jeffrey C

“…An in vivo rat model of disc degeneration with emphasis on characterizing acute and chronic cytokine production. To compare the morphologic and proinflammatory…”
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Spaceflight-induced bone loss alters failure mode and reduces bending strength in murine spinal segments by Berg-Johansen, Britta, Liebenberg, Ellen C., Li, Alfred, Macias, Brandon R., Hargens, Alan R., Lotz, Jeffrey C.

“…ABSTRACT Intervertebral disc herniation rates are quadrupled in astronauts following spaceflight. While bending motions are main contributors to herniation,…”
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Tidemark Avulsions are a Predominant Form of Endplate Irregularity by Berg-Johansen, Britta, Jain, Deeptee, Liebenberg, Ellen C., Fields, Aaron J., Link, Thomas M., O’Neill, Conor W., Lotz, Jeffrey C.

“…STUDY DESIGN.Descriptive histologic and magnetic resonance imaging study of human cadaveric spines. OBJECTIVE.To identify and characterize common endplate…”
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Innervation patterns of PGP 9.5‐positive nerve fibers within the human lumbar vertebra by Bailey, Jeannie F., Liebenberg, Ellen, Degmetich, Sean, Lotz, Jeffrey C.

“…Intervertebral disc injury or degeneration is a common cause of low back pain, and yet the specific source of pain remains ambiguous in many cases. Previous…”
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Influence of biochemical composition on endplate cartilage tensile properties in the human lumbar spine by Fields, Aaron J., Rodriguez, David, Gary, Kaitlyn N., Liebenberg, Ellen C., Lotz, Jeffrey C.

“…ABSTRACT Endplate cartilage integrity is critical to spine health and is presumably impaired by deterioration in biochemical composition. Yet, quantitative…”
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Effects of cell type and configuration on anabolic and catabolic activity in 3D co‐culture of mesenchymal stem cells and nucleus pulposus cells by Ouyang, Ann, Cerchiari, Alec E., Tang, Xinyan, Liebenberg, Ellen, Alliston, Tamara, Gartner, Zev J., Lotz, Jeffrey C.

“…ABSTRACT Tissue engineering constructs to treat intervertebral disc degeneration must adapt to the hypoxic and inflammatory degenerative disc microenvironment…”
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Structured coculture of stem cells and disc cells prevent disc degeneration in a rat model by Allon, Aliza A., PhD, Aurouer, Nicolas, MD, Yoo, Bryan B., BS, Liebenberg, Ellen C., BS, Buser, Zorica, PhD, Lotz, Jeffrey C., PhD

“…Abstract Background context Harnessing the potential of stem cells is an important strategy for regenerative medicine. This study explores the use of bilaminar…”
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Pulsed electromagnetic fields reduce acute inflammation in the injured rat‐tail intervertebral disc by Chan, Andrew K., Tang, Xinyan, Mummaneni, Nikhil V., Coughlin, Dezba, Liebenberg, Ellen, Ouyang, Annie, Dudli, Stefan, Lauricella, Michael, Zhang, Nianli, Waldorff, Erik I., Ryaby, James T., Lotz, Jeffrey C.

“…Pro‐inflammatory cytokines are recognized contributors to intervertebral disc (IVD) degeneration and discogenic pain. We have recently reported the…”
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Microstructural abnormalities are evident by histology but not HR-pQCT at the periosteal cortex of the human tibia under CVD and T2D conditions by Garita, Barbara, Maligro, Jenna, Sadoughi, Saghi, Wu, Po Hung, Liebenberg, Ellen, Horvai, Andrew, Link, Thomas M., Kazakia, Galateia J.

“…Cortical bone microstructure deficits may increase fracture risk in individuals with cardiovascular disease and diabetes. High resolution peripheral…”
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Contribution of the Endplates to Disc Degeneration by Fields, Aaron J., Ballatori, Alexander, Liebenberg, Ellen C., Lotz, Jeffrey C.

“…Purpose of Review The endplates form the interface between the rigid vertebral bodies and compliant intervertebral discs. Proper endplate function involves a…”
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The anabolic effect of plasma-mediated ablation on the intervertebral disc: stimulation of proteoglycan and interleukin-8 production by Kuelling, Fabrice A., MD, Foley, Kevin T., MD, Liu, Jane J., MD, Liebenberg, Ellen, BS, Sin, Anthony H., MD, Matsukawa, Akihiro, MD, PhD, Lotz, Jeffrey C., PhD

“…Abstract Background context Plasma-mediated radiofrequency-based ablation (coblation) is an electrosurgical technique currently used for tissue removal in a…”
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Carpal tunnel pressure alters median nerve function in a dose-dependent manner: a rabbit model for carpal tunnel syndrome by Diao, Edward, Shao, Fang, Liebenberg, Ellen, Rempel, David, Lotz, Jeffrey C.

“…Background: An in vivo animal model for carpal tunnel syndrome (CTS) is presented which allows for graded application of pressure to the median nerve within…”
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Alterations in Intervertebral Disc Composition, Matrix Homeostasis and Biomechanical Behavior in the UCD-T2DM Rat Model of Type 2 Diabetes by Fields, Aaron J., PhD, Berg-Johansen, Britta, MS, Metz, Lionel N., MD, Miller, Stephanie, BS, Brandan La, BS, Liebenberg, Ellen C., BS, Coughlin, Dezba G., PhD, Graham, James L., PhD, Stanhope, Kimber L., PhD, Havel, Peter J., PhD, DVM, Lotz, Jeffrey C., PhD

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Intradiscal thermal therapy does not stimulate biologic remodeling in an in vivo sheep model by BASS, Elisa C, NAU, William H, LOTZ, Jeffrey C, DIEDERICH, Chris J, LIEBENBERG, Ellen, SHU, Richard, PELLEGRINO, Richard, SUTTON, Jeffrey, ATTAWIA, Mohamed, HU, Serena S, FERRIER, William T

“…Thermal energy was delivered in vivo to ovine cervical discs and the postheating response was monitored over time. To determine the effects of two distinctly…”
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Modic type 1 change is an autoimmune response that requires a proinflammatory milieu provided by the ‘Modic disc’ by Dudli, Stefan, Liebenberg, Ellen, Magnitsky, Sergey, Lu, Bochao, Lauricella, Michael, Lotz, Jeffrey C.

“…Modic changes (MCs) are magnetic resonance imaging (MRI) evidence of inflammatory and fibrotic vertebral bone marrow lesions that associate with adjacent disc…”
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Propionibacterium acnes infected intervertebral discs cause vertebral bone marrow lesions consistent with Modic changes by Dudli, Stefan, Liebenberg, Ellen, Magnitsky, Sergey, Miller, Steve, Demir-Deviren, Sibel, Lotz, Jeffrey C.

“…ABSTRACT Modic type I change (MC1) are vertebral bone marrow lesions adjacent to degenerated discs that are specific for discogenic low back pain. The…”
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