Search Results - "LIARD, Francine"

Oral Bioavailability and In Vivo Efficacy of the Helicase-Primase Inhibitor BILS 45 BS against Acyclovir-Resistant Herpes Simplex Virus Type 1 by JIANMIN DUAN, LIUZZI, Michel, PARIS, William, LIARD, Francine, BROWNE, Abigail, DANSEREAU, Nathalie, SIMONEAU, Bruno, FAUCHER, Anne-Marie, CORDINGLEY, Michael G

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Structure−Activity Study on a Novel Series of Macrocyclic Inhibitors of the Hepatitis C Virus NS3 Protease Leading to the Discovery of BILN 2061 by Llinàs-Brunet, Montse, Bailey, Murray D, Bolger, Gordon, Brochu, Christian, Faucher, Anne-Marie, Ferland, Jean Marie, Garneau, Michel, Ghiro, Elise, Gorys, Vida, Grand-Maître, Chantal, Halmos, Ted, Lapeyre-Paquette, Nicole, Liard, Francine, Poirier, Martin, Rhéaume, Manon, Tsantrizos, Youla S, Lamarre, Daniel

“…From the discovery of competitive hexapeptide inhibitors, potent and selective HCV NS3 protease macrocyclic inhibitors have been identified. Structure−activity…”
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Tissue specificity of endothelin binding sites by Bolger, G T, Liard, F, Krogsrud, R, Thibeault, D, Jaramillo, J

“…A measurement was made of the binding of 125I-labeled endothelin (125I-ET) to crude membrane fractions prepared from rat aorta, atrium, ventricle, portal vein,…”
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Vascular reactivity, tissue levels, and binding sites for endothelin: a comparison in the spontaneously hypertensive and Wistar-Kyoto rats by Bolger, G T, Liard, F, Jodoin, A, Jaramillo, J

“…The role of endothelin (ET-1) in mediating the development of blood pressure was investigated in the spontaneously hypertensive (SHR) rat using the…”
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A novel oral vehicle for poorly soluble HSV-helicase inhibitors: PK/PD validations by Duan, Jianmin, Liard, Francine, Paris, William, Lambert, Michelle

“…The current study describes the design and validation of a novel oral vehicle for delivering poorly water-soluble herpes simplex virus (HSV)-helicase…”
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2‘,6‘-Dimethylphenoxyacetyl:  A New Achiral High Affinity P 3 -P 2 Ligand for Peptidomimetic-Based HIV Protease Inhibitors by Beaulieu, Pierre L., Anderson, Paul C., Cameron, Dale R., Croteau, Gilbert, Gorys, Vida, Grand-Maître, Chantal, Lamarre, Daniel, Liard, Francine, Paris, William, Plamondon, Louis, Soucy, François, Thibeault, Diane, Wernic, Dominik, Yoakim, Christiane, Pav, Susan, Tong, Liang

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2‘,6‘-Dimethylphenoxyacetyl:  A New Achiral High Affinity P3-P2 Ligand for Peptidomimetic-Based HIV Protease Inhibitors by Beaulieu, Pierre L, Anderson, Paul C, Cameron, Dale R, Croteau, Gilbert, Gorys, Vida, Grand-Maître, Chantal, Lamarre, Daniel, Liard, Francine, Paris, William, Plamondon, Louis, Soucy, François, Thibeault, Diane, Wernic, Dominik, Yoakim, Christiane, Pav, Susan, Tong, Liang

“…Starting from palinavir (1), our lead HIV protease inhibitor, we have discovered a new series of truncated analogues in which the P3-P2 quinaldic-valine…”
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Pharmacokinetic aspects of palinavir, an HIV protease inhibitor, in Sprague-Dawley rats by Liard, F, Jaramillo, J, Paris, W L, Yoakim, C

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Potent HIV Protease Inhibitors Containing a Novel (Hydroxyethyl)amide Isostere by Beaulieu, Pierre L, Wernic, Dominik, Abraham, Anderson, Paul C, Bogri, Tibor, Bousquet, Yves, Croteau, Gilbert, Guse, Ingrid, Lamarre, Daniel, Liard, Francine, Paris, William, Thibeault, Diane, Pav, Susan, Tong, Liang

“…A series of HIV protease inhibitors containing a novel (hydroxyethyl)amidosuccinoyl core has been synthesized. These peptidomimetic structures inhibit viral…”
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The human renin infused rat: use as an in vivo model for the biological evaluation of human renin inhibitors by Bolger, G, Vigeant, J C, Liard, F, Simoneau, B, Thibeault, D, Pilote, L, Lamarre, D, Jung, G, Anderson, P, Jaramillo, J

“…The human renin infused rat model (HRIRM) was used as an in vivo small-animal model for evaluating the efficacy of a collection of inhibitors of human renin…”
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Tissue selectivity and calcium dependence of contractile responses to endothelin by Bolger, G T, Liard, F, Jaramillo, J

“…The tissue selectivity and calcium dependence of endothelin, a potent vasoconstrictor peptide obtained from endothelial cells, were investigated in a number of…”
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Characterization of intestinal smooth muscle responses and binding sites for endothelin by Bolger, G T, Liard, F, Garneau, M, Jaramillo, J

“…The contractile activity of and binding sites for endothelin-1 (ET-1) were investigated in isolated guinea-pig ileal longitudinal smooth muscle (GPILM). ET-1…”
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Interactions between endothelin and atrial natriuretic factor in the rat aortic ring preparation by Bolger, G, Liard, F, Krogsrud, R, Welchner, E, Jaramillo, J

“…The potential interaction (s) between atrial natriuretic factor (ANF) and porcine--human endothelin (ET-1) was investigated in the endothelium-denuded rat…”
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