Search Results - "LIAO, Serena G"
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Whole-Genome Methylation Sequencing Reveals Distinct Impact of Differential Methylations on Gene Transcription in Prostate Cancer
Published in The American journal of pathology (01-12-2013)“…DNA methylation is one of the most important epigenetic mechanisms in regulating gene expression. Genome hypermethylation has been proposed as a critical…”
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2
Missing value imputation in high-dimensional phenomic data: imputable or not, and how?
Published in BMC bioinformatics (05-11-2014)“…In modern biomedical research of complex diseases, a large number of demographic and clinical variables, herein called phenomic data, are often collected and…”
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An R package suite for microarray meta-analysis in quality control, differentially expressed gene analysis and pathway enrichment detection
Published in Bioinformatics (Oxford, England) (01-10-2012)“…With the rapid advances and prevalence of high-throughput genomic technologies, integrating information of multiple relevant genomic studies has brought new…”
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4
Bias correction for selecting the minimal-error classifier from many machine learning models
Published in Bioinformatics (Oxford, England) (15-11-2014)“…Supervised machine learning is commonly applied in genomic research to construct a classifier from the training data that is generalizable to predict…”
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RNASeqDesign: A framework for RNA-Seq genome-wide power calculation and study design issues
Published in Journal of the Royal Statistical Society. Series C, Applied statistics (01-04-2019)“…Massively parallel sequencing (a.k.a. next-generation sequencing, NGS) technology has emerged as a powerful tool in characterizing genomic profiles. Among many…”
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RNASeqDesign: a framework for ribonucleic acid sequencing genomewide power calculation and study design issues
Published in Journal of the Royal Statistical Society Series C: Applied Statistics (01-04-2019)“…Massively parallel sequencing (also known as next generation sequencing (NGS)) technology has emerged as a powerful tool in characterizing genomic profiles…”
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Targeted DNA Methylation Screen in the Mouse Mammary Genome Reveals a Parity-Induced Hypermethylation of Igf1r That Persists Long after Parturition
Published in Cancer prevention research (Philadelphia, Pa.) (01-10-2015)“…The most effective natural prevention against breast cancer is an early first full-term pregnancy. Understanding how the protective effect is elicited will…”
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Abstract P5-11-05: Pregnancy-induced epigenetic changes in the insulin-like growth factor signaling pathway
Published in Cancer research (Chicago, Ill.) (01-05-2015)“…Abstract Prevention will prove to be the single most effective way of eradicating breast cancer. Currently, the most effective natural breast cancer prevention…”
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Targeted DNA methylation screen in the mouse mammary genome reveals a parity-induced hypermethylation of IGF1R which persists long after parturition
Published in Cancer prevention research (Philadelphia, Pa.) (19-08-2015)“…The most effective natural prevention against breast cancer is an early first full term pregnancy. Understanding how the protective effect is elicited will…”
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