Search Results - "LIANIDOU, Evi"
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Detection and relevance of epigenetic markers on ctDNA: recent advances and future outlook
Published in Molecular oncology (01-06-2021)“…Liquid biopsy, a minimally invasive approach, is a highly powerful clinical tool for the real‐time follow‐up of cancer and overcomes many limitations of tissue…”
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Liquid biopsies
Published in Genes chromosomes & cancer (01-04-2019)“…Liquid biopsy is based on minimally invasive blood tests and has a high potential to significantly change the therapeutic strategy in cancer patients,…”
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Circulating Tumor Cells in Breast Cancer: Detection Systems, Molecular Characterization, and Future Challenges
Published in Clinical chemistry (Baltimore, Md.) (01-09-2011)“…Circulating tumor cell (CTC) analysis is a promising new diagnostic field for estimating the risk for metastatic relapse and metastatic progression in patients…”
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Liquid biopsy in ovarian cancer: the potential of circulating miRNAs and exosomes
Published in Translational research : the journal of laboratory and clinical medicine (01-03-2019)“…Ovarian cancer still remains the most lethal female cancer, since in most cases it is diagnosed at an advanced stage. Usually after completion of primary…”
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Liquid biopsy in ovarian cancer: recent advances on circulating tumor cells and circulating tumor DNA
Published in Clinical chemistry and laboratory medicine (26-01-2018)“…Ovarian cancer remains the most lethal disease among gynecological malignancies despite the plethora of research studies during the last decades. The majority…”
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Circulating cell-free DNA in breast cancer: size profiling, levels, and methylation patterns lead to prognostic and predictive classifiers
Published in Oncogene (02-05-2019)“…Blood circulating cell-free DNA (ccfDNA) is a suggested biosource of valuable clinical information for cancer, meeting the need for a minimally-invasive…”
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The Role of CTCs as Tumor Biomarkers
Published in Advances in experimental medicine and biology (2015)“…Detection of Circulating Tumor Cells (CTCs) in peripheral blood can serve as a "liquid biopsy" approach and as a source of valuable tumor markers. CTCs are…”
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Gene expression profiling and DNA methylation analyses of CTCs
Published in Molecular oncology (01-03-2016)“…A variety of molecular assays have been developed for CTCs detection and molecular characterization. Molecular assays are based on the nucleic acid analysis in…”
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Prognostic Significance of TWIST1 , CD24 , CD44 , and ALDH1 Transcript Quantification in EpCAM-Positive Circulating Tumor Cells from Early Stage Breast Cancer Patients
Published in Cells (Basel, Switzerland) (29-06-2019)“…(1) Background: The aim of the study was to evaluate the prognostic significance of EMT-associated ( and stem-cell (SC) transcript ( , , ) quantification in…”
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Quantification of circulating miRNAs in plasma: effect of preanalytical and analytical parameters on their isolation and stability
Published in The Journal of molecular diagnostics : JMD (01-11-2013)“…Circulating miRNAs are intensively evaluated as promising blood-based biomarkers. This growing interest in developing assays for circulating miRNAs…”
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Gene expression in circulating tumor cells reveals a dynamic role of EMT and PD-L1 during osimertinib treatment in NSCLC patients
Published in Scientific reports (27-01-2021)“…Liquid biopsy is a tool to unveil resistance mechanisms in NSCLC. We studied changes in gene expression in CTC-enriched fractions of EGFR-mutant NSCLC patients…”
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SOX17 promoter methylation in circulating tumor cells and matched cell-free DNA isolated from plasma of patients with breast cancer
Published in Clinical chemistry (Baltimore, Md.) (01-01-2013)“…Detection of circulating tumor cells (CTCs) and cell-free DNA (cfDNA) in the peripheral blood of patients with solid tumors has been widely studied for the…”
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SARS-CoV-2 wastewater surveillance data can predict hospitalizations and ICU admissions
Published in The Science of the total environment (15-01-2022)“…We measured SARS-CoV-2 RNA load in raw wastewater in Attica, Greece, by RT-qPCR for the environmental surveillance of COVID-19 for 6 months. The lag between…”
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ESR1 Methylation: A Liquid Biopsy-Based Epigenetic Assay for the Follow-up of Patients with Metastatic Breast Cancer Receiving Endocrine Treatment
Published in Clinical cancer research (15-03-2018)“…Liquid biopsy provides real-time monitoring of tumor evolution and response to therapy through analysis of circulating tumor cells (CTCs) and…”
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Circulating tumor cells as promising novel biomarkers in solid cancers
Published in Critical reviews in clinical laboratory sciences (01-06-2014)“…Abstract The presence of circulating tumor cells (CTCs) in peripheral blood can serve as a "liquid biopsy" approach and has thus emerged lately as one of the…”
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Prognostic Value of Mature MicroRNA-21 and MicroRNA-205 Overexpression in Non-Small Cell Lung Cancer by Quantitative Real-Time RT-PCR
Published in Clinical chemistry (Baltimore, Md.) (01-10-2008)“…microRNA (miRNA) expression profiles are being intensively investigated for their involvement in carcinogenesis. We evaluated the prognostic value of mature…”
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Molecular characterization of circulating tumor cells in breast cancer: challenges and promises for individualized cancer treatment
Published in Cancer and metastasis reviews (01-12-2012)“…Blood testing using Circulating Tumor Cells (CTCs) has emerged as one of the hottest fields in cancer diagnosis. Research on CTCs present nowadays a challenge,…”
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RASSF1A promoter methylation in high-grade serous ovarian cancer: A direct comparison study in primary tumors, adjacent morphologically tumor cell-free tissues and paired circulating tumor DNA
Published in Oncotarget (28-03-2017)“…The RASSF1A promoter is frequently methylated in high-grade serous ovarian cancer (HGSC). We examined RASSF1A promoter methylation in primary tumors, adjacent…”
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ESR1 methylation in primary tumors and paired circulating tumor DNA of patients with high-grade serous ovarian cancer
Published in Gynecologic oncology (01-08-2018)“…Estrogen receptor, coded by the ESR1 gene, is highly expressed in epithelial ovarian cancer. ESR1 gene is frequently methylated in many types of gynecological…”
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Direct comparison of size-dependent versus EpCAM-dependent CTC enrichment at the gene expression and DNA methylation level in head and neck squamous cell carcinoma
Published in Scientific reports (16-04-2020)“…We directly compared two different approaches used for Circulating Tumor Cell (CTC) isolation, a size-dependent microfluidic system versus an EpCAM-dependent…”
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