Search Results - "LI, Shuangyue"
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Mdivi-1, a mitochondrial fission inhibitor, reduces angiotensin-II- induced hypertension by mediating VSMC phenotypic switch
Published in Biomedicine & pharmacotherapy (01-08-2021)“…Vascular smooth muscle cell (VSMC) phenotypic switch plays an essential role in the pathogenesis of hypertension. Mitochondrial dynamics, such as mitochondrial…”
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Role of Biological Sex in the Cardiovascular-Gut Microbiome Axis
Published in Frontiers in cardiovascular medicine (10-01-2022)“…There has been a recent, unprecedented interest in the role of gut microbiota in host health and disease. Technological advances have dramatically expanded our…”
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Anlotinib Inhibits Proliferation and Induces Apoptosis in B-cell Acute Lymphoblastic Leukemia by Targeting the BTK and AKT/mTOR Pathway
Published in Anti-cancer agents in medicinal chemistry (01-01-2023)“…Acute lymphoblastic leukemia (ALL) is the second most common acute leukemia in adults, whose known drug treatments are limited and expensive. This…”
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Ginsenoside Rg1 inhibits multiple myeloma and overcomes bortezomib resistance through AMPK-mTOR pathway
Published in Heliyon (15-07-2024)“…The resistance of multiple myeloma (MM) to bortezomib (BTZ) has brought multiple challenges to its clinical use. Numerous ginsenosides have potential…”
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Alterations of Gut Microbiome, Metabolome, and Lipidome in Takayasu Arteritis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-02-2023)“…Objective Mounting evidence has linked microbiome and metabolome to systemic autoimmunity and cardiovascular diseases (CVDs). Takayasu arteritis (TAK) is a…”
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Evaluation of PFOS-mediated neurotoxicity in rat primary neurons and astrocytes cultured separately or in co-culture
Published in Toxicology in vitro (01-02-2017)“…Perfluorooctane sulfonate (PFOS) is a potential neurotoxicant reported by epidemiological investigations and experimental studies, while the underlying…”
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NL101 synergizes with the BCL-2 inhibitor venetoclax through PI3K-dependent suppression of c-Myc in acute myeloid leukaemia
Published in Journal of translational medicine (27-09-2024)“…Acute myeloid leukaemia (AML) comprises a group of heterogeneous and aggressive haematological malignancies with unsatisfactory prognoses and limited treatment…”
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Optimization of Tuina rolling manipulation parameters to promote blood circulation using a circulatory orthogonal experiment
Published in Journal of Physical Therapy Science (01-01-2024)“…[Purpose] To determine the optimal Tuina rolling manipulation parameters for improving peripheral blood circulation and to observe the duration of these…”
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Posaconazole oral suspension for secondary antifungal prophylaxis in allogeneic stem cell transplantation recipients: a retrospective study
Published in BMC infectious diseases (15-05-2022)“…There is no consensus on the optimal secondary antifungal prophylaxis (SAP) regimen in patients receiving allogeneic hematopoietic stem cell transplantation…”
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Bone marrow mesenchymal stem cells conditioned medium protects VSC4.1 cells against 2,5-hexanedione-induced autophagy via NGF-PI3K/Akt/mTOR signaling pathway
Published in Brain research (01-10-2018)“…•BMSC-CM prevents HD-induced VSC4.1 cell damage by suppressing autophagy.•BMSC-CM elevated NGF and p-TrkA expressions in HD-treated cells.•NGF inhibited…”
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High expression of EBP is an adverse prognostic factor for de novo acute myeloid leukemia
Published in Hematology (Luxembourg) (01-12-2024)“…Acute myeloid leukemia (AML) is a heterogeneous disease, for which identifying reliable prognostic markers is critical for accurate clinical prognosis and…”
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Taurine inhibits neuron apoptosis in hippocampus of diabetic rats and high glucose exposed HT-22 cells via the NGF-Akt/Bad pathway
Published in Amino acids (01-01-2020)“…Type 2 Diabetes causes learning and memory deficits that might be mediated by hippocampus neuron apoptosis. Studies found that taurine might improve cognitive…”
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Oxycodone is superior to morphine for pain relief following peroral oesophageal myotomy: a prospective, randomized, controlled trial
Published in Wideochirurgia i inne techniki mało inwazyjne (01-12-2022)“…Patients underwent peroral endoscopic myotomy (POEM) for treating achalasia suffered with mild to moderate, sometimes even severe postoperative pain. To…”
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Intensified conditioning regimen with fludarabine combined with post-transplantation cyclophosphamide for haploidentical allogeneic hematopoietic stem cell transplantation in children with high-risk acute leukemia
Published in Hematology (Luxembourg) (31-12-2023)“…Post-transplantation cyclophosphamide (PTCy) can reduce the incidence of graft versus host disease (GVHD) and this intervention is often applied on adults with…”
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15
Protection of Taurine Against PFOS-Induced Neurotoxicity in PC12 Cells
Published in Advances in experimental medicine and biology (2017)“…As a new member of persistent organic pollutants, the potent neurotoxicity of perfluorooctane sulfonates (PFOS) found in epidemiological studies and laboratory…”
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2,5-hexanedione downregulates nerve growth factor and induces neuron apoptosis in the spinal cord of rats via inhibition of the PI3K/Akt signaling pathway
Published in PloS one (27-06-2017)“…2,5-hexanedione (2,5-HD) is the main active metabolite of n-hexane and induces apoptosis in nerve tissue, however, the mechanism of which remains unclear. In…”
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Bone marrow mesenchymal stem cells promote remyelination in spinal cord by driving oligodendrocyte progenitor cell differentiation via TNFα/RelB-Hes1 pathway: a rat model study of 2,5-hexanedione-induced neurotoxicity
Published in Stem cell research & therapy (04-08-2021)“…Abstract Background N -hexane, with its metabolite 2,5-hexanedine (HD), is an industrial hazardous material. Chronic hexane exposure causes segmental…”
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Taurine inhibits 2,5-hexanedione-induced oxidative stress and mitochondria-dependent apoptosis in PC12 cells
Published in Industrial Health (2017)“…2,5-hexanedione (HD) is the ultimate neurotoxic metabolite of hexane, causing the progression of nerve diseases in human. It was reported that HD induced…”
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Neuroprotection by Taurine on HBCD-Induced Apoptosis in PC12 Cells
Published in Advances in experimental medicine and biology (2017)“…Hexabromocyclododecane (HBCD) is a widely used brominated flame retardant (BFR). Because of their presence in human issues, including brain tissue, concern has…”
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Soy Isoflavone Protects Myocardial Ischemia/Reperfusion Injury through Increasing Endothelial Nitric Oxide Synthase and Decreasing Oxidative Stress in Ovariectomized Rats
Published in Oxidative medicine and cellular longevity (01-01-2016)“…There is a special role for estrogens in preventing and curing cardiovascular disease in women. Soy isoflavone (SI), a soy-derived phytoestrogen, has similar…”
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