Search Results - "LI, Ningning"
-
1
Architecture of the mammalian mechanosensitive Piezo1 channel
Published in Nature (London) (05-11-2015)“…Piezo proteins are evolutionarily conserved and functionally diverse mechanosensitive cation channels. However, the overall structural architecture and gating…”
Get full text
Journal Article -
2
Structural remodeling of ribosome associated Hsp40-Hsp70 chaperones during co-translational folding
Published in Nature communications (14-06-2022)“…Ribosome associated complex (RAC), an obligate heterodimer of HSP40 and HSP70 (Zuo1 and Ssz1 in yeast), is conserved in eukaryotes and functions as…”
Get full text
Journal Article -
3
Stable Recovery of Sparsely Corrupted Signals Through Justice Pursuit De-Noising
Published in Journal of computational mathematics (01-01-2024)Get full text
Journal Article -
4
Structure of a Pancreatic ATP-Sensitive Potassium Channel
Published in Cell (12-01-2017)“…ATP-sensitive potassium channels (KATP) couple intracellular ATP levels with membrane excitability. These channels play crucial roles in many essential…”
Get full text
Journal Article -
5
Structure of the eukaryotic MCM complex at 3.8 Å
Published in Nature (London) (13-08-2015)“…DNA replication in eukaryotes is strictly regulated by several mechanisms. A central step in this replication is the assembly of the heterohexameric…”
Get full text
Journal Article -
6
A Novel Frequency and Voltage Control Method for Islanded Microgrid Based on Multienergy Storages
Published in IEEE transactions on smart grid (01-01-2016)“…A microgrid (MG) can operate in both grid-tied and autonomous mode. Without the support from the public utility, the control of an autonomous MG is more…”
Get full text
Journal Article -
7
Effects of dyadic patterns and proficiency pairing on Chinese EFL learners’ second language learning in collaborative writing
Published in Frontiers in psychology (20-10-2022)“…Research on Collaborative Writing (CW) has proliferated over recent decades, but the role that pair dynamics plays in second language (L2) learning remains…”
Get full text
Journal Article -
8
Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion
Published in Nature neuroscience (01-04-2018)“…Newborn microglia rapidly replenish the whole brain after selective elimination of most microglia (>99%) in adult mice. Previous studies reported that…”
Get full text
Journal Article -
9
Hypericin Ameliorates Depression-like Behaviors via Neurotrophin Signaling Pathway Mediating m6A Epitranscriptome Modification
Published in Molecules (Basel, Switzerland) (03-05-2023)“…Hypericin, one of the major antidepressant constituents of St. John's wort, was shown to exert antidepressant effects by affecting cerebral CYP enzymes,…”
Get full text
Journal Article -
10
Hexavalent chromium caused DNA damage repair and apoptosis via the PI3K/AKT/FOXO1 pathway triggered by oxidative stress in the lung of rat
Published in Ecotoxicology and environmental safety (15-11-2023)“…Hexavalent chromium [Cr(VI)] is an occupational carcinogen that accumulates in the lungs and causes lung injury and even lung cancer. 36 SD male rats received…”
Get full text
Journal Article -
11
Exon-intron boundary inhibits m6A deposition, enabling m6A distribution hallmark, longer mRNA half-life and flexible protein coding
Published in Nature communications (13-07-2023)“…Regional bias of N 6 -methyladenosine (m 6 A) mRNA modification avoiding splice site region, calls for an open hypothesis whether exon-intron boundary could…”
Get full text
Journal Article -
12
MYC and the unfolded protein response in cancer: synthetic lethal partners in crime?
Published in EMBO molecular medicine (08-05-2020)“…The transcription factors of the MYC family play pivotal roles in the initiation and progression of human cancers. High oncogenic level of MYC invades…”
Get full text
Journal Article -
13
Structure of the origin recognition complex bound to DNA replication origin
Published in Nature (London) (01-07-2018)“…The six-subunit origin recognition complex (ORC) binds to DNA to mark the site for the initiation of replication in eukaryotes. Here we report a 3 Å…”
Get full text
Journal Article -
14
Open-ringed structure of the Cdt1–Mcm2–7 complex as a precursor of the MCM double hexamer
Published in Nature structural & molecular biology (01-03-2017)“…A high-resolution cryo-EM structure of the heptameric Cdt1–Mcm2–7 complex of the replicative helicase from budding yeast suggests a ‘spring-action’…”
Get full text
Journal Article -
15
Multibit Optoelectronic Memory in Top‐Floating‐Gated van der Waals Heterostructures
Published in Advanced functional materials (01-09-2019)“…Nonvolatile memories based on van der Waals heterostructures have been proved to be promising candidates for next‐generation data storage devices. However,…”
Get full text
Journal Article -
16
Structural insights into TSC complex assembly and GAP activity on Rheb
Published in Nature communications (12-01-2021)“…Tuberous sclerosis complex (TSC) integrates upstream stimuli and regulates cell growth by controlling the activity of mTORC1. TSC complex functions as a…”
Get full text
Journal Article -
17
A commentary of “Initial DNA melting in human DNA replication initiation”: Top 10 Scientific Advances of 2023, China
Published in Fundamental research (Beijing) (01-05-2024)Get full text
Journal Article -
18
Association between vitamin D concentration and delirium in hospitalized patients: A meta-analysis
Published in PloS one (08-02-2023)“…Now the occurrence of delirium is more concerning to clinicians and psychiatrists. It has been reported that vitamin D deficiency may be a relevant factor in…”
Get full text
Journal Article -
19
Fluoxetine regulates eEF2 activity (phosphorylation) via HDAC1 inhibitory mechanism in an LPS-induced mouse model of depression
Published in Journal of neuroinflammation (01-02-2021)“…Selective serotonin reuptaker inhibitors, including fluoxetine, are widely studied and prescribed antidepressants, while their exact molecular and cellular…”
Get full text
Journal Article -
20
Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System
Published in Cell (04-04-2019)“…Contractile injection systems (CISs) are cell-puncturing nanodevices that share ancestry with contractile tail bacteriophages. Photorhabdus virulence cassette…”
Get full text
Journal Article