Search Results - "LI, Jieru"

Volumetric interferometric lattice light-sheet imaging by Cao, Bin, Coelho, Simao, Li, Jieru, Wang, Guanshi, Pertsinidis, Alexandros

“…Live cell imaging with high spatiotemporal resolution and high detection sensitivity facilitates the study of the dynamics of cellular structure and function…”
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Beneficial effects of paeoniflorin on non-alcoholic fatty liver disease induced by high-fat diet in rats by Ma, Zhihong, Chu, Li, Liu, Hongying, Wang, Weijie, Li, Jieru, Yao, Wenzao, Yi, Jianfeng, Gao, Yue

“…Non-alcoholic fatty liver disease (NAFLD) is the most prevalent form of chronic liver diseases. This study sought to evaluate the insulin-sensitizing effect of…”
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STREAMING-tag system reveals spatiotemporal relationships between transcriptional regulatory factors and transcriptional activity by Ohishi, Hiroaki, Shimada, Seiru, Uchino, Satoshi, Li, Jieru, Sato, Yuko, Shintani, Manabu, Owada, Hitoshi, Ohkawa, Yasuyuki, Pertsinidis, Alexandros, Yamamoto, Takashi, Kimura, Hiroshi, Ochiai, Hiroshi

“…Transcription is a dynamic process. To detect the dynamic relationship among protein clusters of RNA polymerase II and coactivators, gene loci, and…”
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Single-gene imaging links genome topology, promoter–enhancer communication and transcription control by Li, Jieru, Hsu, Angela, Hua, Yujing, Wang, Guanshi, Cheng, Lingling, Ochiai, Hiroshi, Yamamoto, Takashi, Pertsinidis, Alexandros

“…Transcription activation by distal enhancers is essential for cell-fate specification and maintenance of cellular identities. How long-range gene regulation is…”
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CFLAP1 and CFLAP2 Are Two bHLH Transcription Factors Participating in Synergistic Regulation of AtCFL1-Mediated Cuticle Development in Arabidopsis by Li, Shibai, Wang, Xiaochen, He, Shan, Li, Jieru, Huang, Qingpei, Imaizumi, Takato, Qu, Leqing, Qin, Genji, Qu, Li-Jia, Gu, Hongya

“…The cuticle is a hydrophobic lipid layer covering the epidermal cells of terrestrial plants. Although many genes involved in Arabidopsis cuticle development…”
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ADP1 affects plant architecture by regulating local auxin biosynthesis by Li, Ruixi, Li, Jieru, Li, Shibai, Qin, Genji, Novák, Ondřej, Pěnčík, Aleš, Ljung, Karin, Aoyama, Takashi, Liu, Jingjing, Murphy, Angus, Gu, Hongya, Tsuge, Tomohiko, Qu, Li-Jia

“…Plant architecture is one of the key factors that affect plant survival and productivity. Plant body structure is established through the iterative initiation…”
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Experimental Study on the Penetration of Natural Unsaturated and Collapsible Loess Based on the Permeability Velocity by Wen, Xin, Jing, Yanlin, Hu, Zhiping, Shao, Jigang, Li, Jieru, Wang, Rui

“…It is of great importance to study the behavior of loess moisture infiltration based on the loess permeability velocity to prevent geological disasters by…”
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A novel and low-toxic peptide DR3penA alleviates pulmonary fibrosis by regulating the MAPK/miR-23b-5p/AQP5 signaling axis by Wang, Dan, Deng, Bochuan, Cheng, Lu, Li, Jieru, Zhang, Jiao, Zhang, Xiang, Guo, Xiaomin, Yan, Tiantian, Yue, Xin, An, Yingying, Zhang, Bangzhi, Yang, Wenle, Xie, Junqiu, Wang, Rui

“…Pulmonary fibrosis (PF) is a pathological change caused by repeated injuries and repair dysfunction of the alveolar epithelium. Our previous study revealed…”
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New insights into promoter-enhancer communication mechanisms revealed by dynamic single-molecule imaging by Li, Jieru, Pertsinidis, Alexandros

“…Establishing cell-type-specific gene expression programs relies on the action of distal enhancers, cis-regulatory elements that can activate target genes over…”
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Single-Molecule Nanoscopy Elucidates RNA Polymerase II Transcription at Single Genes in Live Cells by Li, Jieru, Dong, Ankun, Saydaminova, Kamola, Chang, Hill, Wang, Guanshi, Ochiai, Hiroshi, Yamamoto, Takashi, Pertsinidis, Alexandros

“…Transforming the vast knowledge from genetics, biochemistry, and structural biology into detailed molecular descriptions of biological processes inside cells…”
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Nanoscale nuclear environments, fine-scale 3D genome organization and transcription regulation by Li, Jieru, Pertsinidis, Alexandros

“…Decades of in vitro biochemical reconstitution, genetics and structural biology studies have established a vast knowledge base on the molecular mechanisms of…”
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Meta separation–fusion for generalizable person re-identification by Du, Haishun, He, Linbing, Guo, Jiangtao, Li, Jieru

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Self-assembled metal-polyphenolic based multifunctional nanomedicine to improve therapy treatment of pancreatic cancer by inhibition of glutamine metabolism by Dai, Yiwei, Li, Jieru, Wang, Tao, Zhang, Xinyu, Du, Pengcheng, Dong, Yuman, Jiao, Zuoyi

“…Cancer poses a significant threat to human health and life. Chemotherapy, immunotherapy and chemodynamic therapy (CDT) are effective treatments for cancer…”
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A facile one-step self-assembly strategy for constructing biocompatible and pH-sensitive polyphenol-based nanoparticles for high-efficiency tumor therapy by Dong, Yuman, Li, Jieru, Wang, Tao, Dai, Yiwei, Guo, Shimeng, Zhao, Liangtao, Du, Pengcheng

“…[Display omitted] •A simple and efficient strategy for biocompatible and pH-sensitive polyphenol-based nanoparticles.•Highly biocompatible, satisfactory safety…”
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The novel peptide DR4penA attenuates the bleomycin‐ and paraquat‐induced pulmonary fibrosis by suppressing the TGF‐β/Smad signaling pathway by Wang, Dan, Deng, Bochuan, Cheng, Lu, Li, Jieru, Guo, Xiaomin, Zhang, Jiao, Zhang, Xiang, Su, Ping, Li, Guofeng, Miao, Xiaokang, Yang, Wenle, Xie, Junqiu, Wang, Rui

“…Pulmonary fibrosis (PF), which is caused by continuous alveolar epithelial cell injury and abnormal repair, is referred to as a difficult disease of the lung…”
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The Peptide DH α -(4-pentenyl)-ANPQIR-NH 2 Exhibits Antifibrotic Activity in Multiple Pulmonary Fibrosis Models Induced by Particulate and Soluble Chemical Fibrogenic Agents by Li, Jieru, Deng, Bochuan, Zhang, Jiao, Zhang, Xiang, Cheng, Lu, Li, Guofeng, Su, Ping, Miao, Xiaokang, Yang, Wenle, Xie, Junqiu, Wang, Rui

“…Interstitial lung diseases (ILDs) are a group of restrictive lung diseases characterized by interstitial inflammation and pulmonary fibrosis. The incidence of…”
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Paeoniflorin alleviates non-alcoholic steatohepatitis in rats: Involvement with the ROCK/NF-κB pathway by Ma, Zhihong, Chu, Li, Liu, Hongying, Li, Jieru, Zhang, Yuanyuan, Liu, Wentai, Dai, Jun, Yi, Jianfeng, Gao, Yue

“…Paeoniflorin (PF) is one of the major active ingredients of Paeonia lactiflora and has been suggested as a dietary therapy for non-alcoholic steatohepatitis…”
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DR7dA, a Novel Antioxidant Peptide Analog, Demonstrates Antifibrotic Activity in Pulmonary Fibrosis In Vivo and In Vitro by Cheng, Lu, Wang, Dan, Deng, Bochuan, Li, Jieru, Zhang, Jiao, Guo, Xiaomin, Yan, Tiantian, Yue, Xin, An, Yingying, Zhang, Bangzhi, Xie, Junqiu

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Peptide DR8 analogs alleviate pulmonary fibrosis via suppressing TGF-β1 mediated epithelial-mesenchymal transition and ERK1/2 pathway in vivo and in vitro by Wang, Dan, Cheng, Lu, Li, Jieru, Deng, Bochuan, Yan, Tiantian, Yue, Xin, Zhang, Jianfeng, Zhang, Bangzhi, Xie, Junqiu

“…•Asp1, His2, Pro5 and Gln6 are key residues of DR8 determined by amino scanning.•Analogs DR8–3D and DR8–8A inhibit TGF-β1-induced epithelial-mesenchymal…”
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Ginsenoside Rb1 alleviates chronic intermittent hypoxia-induced diabetic cardiomyopathy in db/db mice by regulating the adenosine monophosphate-activated protein kinase/Nrf2/heme oxygenase-1 signaling pathway by LIU, Bingbing, LI, Jieru, SI, Jianchao, CHEN, Qi, YANG, Shengchang, JI, Ensheng

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