Search Results - "LEZHAVA, T"

Epigenetic Activation of Ribosomal Cistrons in Chromatids of Acrocentric Chromosome 15 in Lung Cancer by Lezhava, T., Buadze, T., Mikaia, N., Jokhadze, T., Sigua, T., Gaiozishvili, M., Melkadze, T.

“…After the Human Genome Project was declared complete, the strategic focus area of contemporary genetics shifted towards functional genomics whose research…”
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Thermal stability of blood plasma proteins of breast cancer patients, DSC study by Kikalishvili, L., Ramishvili, M., Nemsadze, G., Lezhava, T., Khorava, P., Gorgoshidze, M., Kiladze, M., Monaselidze, J.

“…The thermodynamic stability of blood plasma main proteins of 17 patients (32–72-year-old women) with preliminary diagnosis of ductal carcinoma was studied. We…”
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EPIGENETIC MODIFICATION UNDER THE INFLUENCE OF PEPTIDE BIOREGULATORS ON "AGED" HETEROCHROMATIN by Lezhava, T, Jokhadze, T, Monaselidze, J, Buadze, T, Gaiozishvili, M, Sigua, T

“…Following the completion of the Human Genome Project, the strategic direction of modern genetics has moved toward functional genomics, to explore the functions…”
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COMPARATIVE ANALYSIS OF WHOLE CARTILAGE TISSUE THERMOSTABILITY IN DISEASED PATIENTS VERSUS INJURED PATIENTS by Monaselidze, J, Kikalishvili, L, Sharia, Sh, Ramishvili, M, Lezhava, T

“…We conducted comparative thermodynamic analysis of femoral cartilages tissue of injured (healthy) patients and patients with congenital hip dislocation. It is…”
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Epigenetic Changes of Activity of the Ribosomal Cistrons of Human Acrocentric Chromatids in Fetuses, Middle-aged (22–45 years) and Old Individuals (80–106 years) by Lezhava, T., Buadze, T., Monaselidze, J., Jokhadze, T., Sigua, N., Jangulashvili, N., Gaiozishvili, M., Koridze, M., Zosidze, N., Rukhadze, M.

“…The level of total heterochromatin, Ag-positive nucleolar organiser regions (NORs) heterochromatin, non-associated and associated heterochromatin satellite…”
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Impact of unfounded vaccine safety concerns on the nationwide measles–rubella immunization campaign, Georgia, 2008 by Khetsuriani, N, Imnadze, P, Baidoshvili, L, Jabidze, L, Tatishili, N, Kurtsikashvili, G, Lezhava, T, Laurent, E, Martin, R

“…Abstract Vaccine safety fears following media reports of adverse events led to low (50.3%) coverage in a supplementary measles–rubella immunization campaign in…”
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Extracellular matrix thermostability of breast gland carcinoma by Monaselisdze, J, Lezhava, T, Nemsadze, G, Kikalishvili, L, Ramishvili, M

“…Thermostability of epithelial cell matrix in composition of normal and breast ductal carcinoma tissues at various stages of the disease has been studied in the…”
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Influence of tetrapeptide on chromatin thermostability by Monaselidze, J, Gorgoshidze, M, Jokhadze, T, Gaiozishvili, M, Lezhava, T

“…It is known that short peptides are capable to interact with DNA, as a result of changes in particular gene expression. In the given work, influence of…”
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Effect of the Peptide Bronchogen (Ala-Asp-Glu-Leu) on DNA Thermostability by Monaselidze, J. R, Khavinson, V. Kh, Gorgoshidze, M. Z, Khachidze, D. G, Lomidze, E. M, Jokhadze, T. A, Lezhava, T. A

“…Thermodynamic parameters of DNA melting in the presence of a peptide bronchogen in various concentrations were estimated on a differential scanning…”
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Mathematical model for satellite associations of human acrocentric chromosomes by Lezhava, T, Tsigroshvili, Z, Dvalishvili, N, Jokhadze, T

“…Short arms, satellite stalks and satellites of human acrocentric chromosomes (13, 14, 15, 21 and 22) represent heterochromatic regions. Enforced by mutual…”
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Natural and artefactual aneuploidy in human lymphocytes in extreme old age by Lezhava, T, Khmaladze, E, Lokhadze, T, Buadze, T

“…At present it is generally believed that aging is accompanied by an increase in the numbers of cells with altered chromosome sets. However, the problem of…”
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Microcalorimetric study of human blood lymphocytes culture at presence of copper, cadmium and prostamax by Kiladze, M, Gorgoshidze, M, Monaselidze, J, Jokhadze, T, Lezhava, T

“…Research goal was study of separate and joint influence of bioregulator prostamax and Cu(II) and Cd(II) ions on the chromatin structure in situ. The thermal…”
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The effect of heavy metal ions and peptide bioregulators on the expression of chromosome fragile sites in the individuals of different age groups and breast cancer patients by Dzhokhadze, T A, Ganozishvili, M N, Lezhava, T A

“…Expression rates of chromosome fragile sites in peripheral blood lymphocytes have been studied in clinically healthy individuals of different age groups (20-38…”
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Thermodynamic properties of blood plasma of patient suffering from atherosclerosis by Monaselidze, J, Barbakadze, Sh, Iladze, M, Kuchadze, Z, Lezhava, T

“…The goal of the work is to find out the changes in the heat parameters of blood plasma denaturation of a son and a granddaughter, in comparison with the same…”
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The microcalorimetric investigation of cellular suspensions of blood lymphocytes from healthily and suffering from atherosclerosis individuals by Monaselidze, J, Barbakadze, Sh, Gorgoshidze, M, Lezhava, T, Jokhadze, T

“…The denaturation thermodynamic parameters--enthalpy (DeltaH) and temperature of hetero-and active chromatin of lymphocytes and metabolic heat of these cells…”
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Academician of the Georgian Academy of Sciences D. I. Dzhaparidze (1933–2008) by Marsagishvili, T., Lezhava, T., Damaskin, B. B., Grafov, B. M., Petry, O. A.

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Association of genes polymorphisms with warfarin dose requirement in georgian population by Tchitashvili, G., Kakauridze, N., Buadze, T., Gaiozishvili, M., Lezhava, T.

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Variability of C-structural heterochromatin in cells derived from the patients with cardiomiopathy and from their relatives by Dzhokhadze, T A, Kakhidze, Kh R, Rogava, M A, Lezhava, T A

“…Variability of C-structural heterochromatin segments in chromosome 1,9 and 16 has been studied in lymphocyte cultures of peripheral blood taken from the…”
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Variability of radiation-induced adaptive response in old age individuals and their correction by Peptide bioregulator -Livagen by Dzhokhadze, T A, Buadze, T Zh, Dvalishvili, N A, Lezhava, T A

“…Effect of aging on adaptive response of cellular systems to low (stimulated) dozes of gamma-rays (0, 2 and 0, 5 Gy) and to disturbing dozes of radiation (1 and…”
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Anti-aging peptide bioregulators induce reactivation of chromatin by Lezhava, T, Monaselidze, J, Kadotani, T, Dvalishvili, N, Buadze, T

“…The effect of synthetic peptide bioregulators (Epitalon, Livagen and Vilon) on structural and facultative heterochromatin of cultivated lymphocytes have been…”
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