Search Results - "LEWALLEN, Michelle E"

MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer by Chaika, Nina V, Gebregiworgis, Teklab, Lewallen, Michelle E, Purohit, Vinee, Radhakrishnan, Prakash, Liu, Xiang, Zhang, Bo, Mehla, Kamiya, Brown, Roger B, Caffrey, Thomas, Yu, Fang, Johnson, Keith R, Powers, Robert, Hollingsworth, Michael A, Singh, Pankaj K

“…Aberrant glucose metabolism is one of the hallmarks of cancer that facilitates cancer cell survival and proliferation. Here, we demonstrate that MUC1, a large,…”
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Cyclin-Dependent Kinase 5 Is Amplified and Overexpressed in Pancreatic Cancer and Activated by Mutant K-Ras by EGGERS, John P, GRANDGENETT, Paul M, OUELLETTE, Michel, HOLLINGSWORTH, Michael A, COLLISSON, Eric C, LEWALLEN, Michelle E, TREMAYNE, Jarrod, SINGH, Pankaj K, SWANSON, Benjamin J, ANDERSEN, Judy M, CAFFREY, Thomas C, HIGH, Robin R

“…To evaluate the nature of cyclin-dependent kinase 5 (CDK5) hyperactivity in pancreatic cancer progression. We used genetic, biochemical, and molecular biology…”
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MUC1 regulates expression of multiple microRNAs involved in pancreatic tumor progression, including the miR-200c/141 cluster by Mohr, Ashley M, Bailey, Jennifer M, Lewallen, Michelle E, Liu, Xiang, Radhakrishnan, Prakash, Yu, Fang, Tapprich, William, Hollingsworth, Michael A

“…MUC1 is a transmembrane glycoprotein that modulates transcription via its cytoplasmic domain. We evaluated the capacity of MUC1 to regulate the global…”
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The glycoprotein mucin‐1 negatively regulates GalNAc transferase 5 expression in pancreatic cancer by Caffrey, Thomas, Sagar, Satish, Thomas, Divya, Lewallen, Michelle E., Hollingsworth, Michael A., Radhakrishnan, Prakash

“…Aberrant expression of the glycoprotein mucin‐1 (MUC1) has been associated with pancreatic cancer progression and metastasis as a result of mediating the…”
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MUC1 Negatively Regulates GalNAc Transferase 5 Expression in Pancreatic Cancer by Caffrey, Thomas, Sagar, Satish, Thomas, Divya, Lewallen, Michelle E, Hollingsworth, Michael A, Radhakrishnan, Prakash

“…Aberrant expression of MUC1 glycoprotein has been associated with pancreatic cancer (PC) progression and metastasis and mediates oncogenic transcriptional…”
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Abstract 2308: MUC1 modulation of E-cadherin through miR-200c and ZEB1 by Mohr, Ashley M., Lewallen, Michelle E., Radhakrishnan, Prakash, Liu, Xiang, Bailey, Jennifer M., Hollingsworth, Michael A.

“…MUC1, a cell-surface glycoprotein implicated in tumorigenesis and metastasis, has a cytoplasmic tail (MUC1.CT) that is phosphorylated by different receptor…”
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Cyclin Dependent Kinase 5 is amplified and over-expressed in pancreatic cancer and activated by mutant K-Ras by Eggers, John P., Grandgenett, Paul M., Collisson, Eric C., Lewallen, Michelle E., Tremayne, Jarrod, Singh, Pankaj K., Swanson, Benjamin J., Andersen, Judy M., Caffrey, Thomas C., High, Robin R., Ouellette, Michel, Hollingsworth, Michael A.

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