Search Results - "LEVY, Gary A"
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Beneficial effects of novel aureobasidium pullulans strains produced beta-1,3-1,6 glucans on interleukin-6 and D-dimer levels in COVID-19 patients; results of a randomized multiple-arm pilot clinical study
Published in Biomedicine & pharmacotherapy (01-01-2022)“…In this pilot clinical study, we report the beneficial effects of beta glucans derived from two strains AFO-202 and N-163 of a black yeast Aureobasidium…”
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2
FGL2 promotes tumour growth and attenuates infiltration of activated immune cells in melanoma and ovarian cancer models
Published in Scientific reports (08-01-2024)“…The tumour microenvironment is infiltrated by immunosuppressive cells, such as regulatory T cells (Tregs), which contribute to tumour escape and impede…”
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3
GITR intrinsically sustains early type 1 and late follicular helper CD4 T cell accumulation to control a chronic viral infection
Published in PLoS pathogens (01-01-2015)“…CD4 T cells are critical for control of persistent infections; however, the key signals that regulate CD4 T help during chronic infection remain incompletely…”
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4
Antiviral Treatment of Recurrent Hepatitis C After Liver Transplantation: Predictors of Response and Long-Term Outcome
Published in Transplantation (27-11-2009)“…Efficacy and long-term outcome of antiviral therapy for recurrent hepatitis C after liver transplantation is poorly defined. This study aimed at assessing the…”
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Subnormothermic ex vivo liver perfusion reduces endothelial cell and bile duct injury after donation after cardiac death pig liver transplantation
Published in Liver transplantation (01-11-2014)“…An ischemic‐type biliary stricture (ITBS) is a common feature after liver transplantation using donation after cardiac death (DCD) grafts. We compared…”
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6
Protective effects of long pentraxin PTX3 on lung injury in a severe acute respiratory syndrome model in mice
Published in Laboratory investigation (01-09-2012)“…The outbreak of severe acute respiratory syndrome (SARS) in 2003 reinforces the potential of lethal pandemics of respiratory viral infections. The underlying…”
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7
Therapeutic drug monitoring of immunosuppressant drugs in clinical practice
Published in Clinical therapeutics (01-03-2002)“…Background: Therapeutic drug monitoring (TDM) is essential to maintain the efficacy of many immunosuppressant drugs while minimizing their toxicity. TDM has…”
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8
Two unique biological response-modifier glucans beneficially regulating gut microbiota and faecal metabolome in a non-alcoholic steatohepatitis animal model, with potential applications in human health and disease
Published in BMJ open gastroenterology (01-09-2022)“…ObjectiveThe gut microbiome and its metabolites are influenced by age and stress and reflect the metabolism and health of the immune system. We assessed the…”
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9
Generation of Antigen Microarrays to Screen for Autoantibodies in Heart Failure and Heart Transplantation
Published in PloS one (11-03-2016)“…Autoantibodies directed against endogenous proteins including contractile proteins and endothelial antigens are frequently detected in patients with heart…”
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10
Murine Hepatitis Virus Strain 1 Produces a Clinically Relevant Model of Severe Acute Respiratory Syndrome in A/J Mice
Published in Journal of Virology (01-11-2006)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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11
FGL2/Fibroleukin mediates hepatic reperfusion injury by induction of sinusoidal endothelial cell and hepatocyte apoptosis in mice
Published in Journal of hepatology (01-01-2012)“…Background & Aims Sinusoidal endothelial cell (SEC) and hepatocyte death are early, TNF-α mediated events in ischemia and reperfusion of the liver (I/Rp). We…”
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12
Radiotherapy as a bridge to liver transplantation for hepatocellular carcinoma
Published in Transplant international (01-03-2010)“…About 20% of the patients with advanced hepatocellular carcinoma (HCC) who are listed for liver transplantation (LT) are eventually delisted as a result of…”
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13
Targeted deletion of FGL2 leads to increased early viral replication and enhanced adaptive immunity in a murine model of acute viral hepatitis caused by LCMV WE
Published in PloS one (11-10-2013)“…Mounting effective innate and adaptive immune responses are critical for viral clearance and the generation of long lasting immunity. It is known that…”
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14
Right lobe living-donor hepatectomy—the Toronto approach, tips and tricks
Published in Hepatobiliary surgery and nutrition (01-04-2016)“…Living-donor liver transplantation (LDLT) is a well-established treatment for end-stage liver disease. Nevertheless, it has not been extensively accepted in…”
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High preoperative bilirubin values protect against reperfusion injury after live donor liver transplantation
Published in Transplant international (01-11-2015)“…Heme Oxygenase-1 and its product biliverdin/bilirubin have been demonstrated to protect against ischemia/reperfusion injury (IRI). We investigated whether…”
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Recipient age affects long‐term outcome and hepatitis C recurrence in old donor livers following transplantation
Published in Liver transplantation (01-10-2009)“…We studied the role of donor and recipient age in transplantation/ischemia‐reperfusion injury (TIRI) and short‐ and long‐term graft and patient survival. Eight…”
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The Fgl2/fibroleukin prothrombinase contributes to immunologically mediated thrombosis in experimental and human viral hepatitis
Published in The Journal of clinical investigation (01-07-2003)“…Fibrin deposition and thrombosis within the microvasculature is now appreciated to play a pivotal role in the hepatocellular injury observed in experimental…”
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Endothelial Induction of fgl2 Contributes to Thrombosis during Acute Vascular Xenograft Rejection
Published in The Journal of immunology (1950) (01-05-2004)“…Thrombosis is a prominent feature of acute vascular rejection (AVR), the current barrier to survival of pig-to-primate xenografts. Fibrinogen-like protein 2…”
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Does microvascular invasion affect outcomes after liver transplantation for HCC? A histopathological analysis of 155 consecutive explants
Published in Journal of gastrointestinal surgery (01-04-2007)“…Macroscopic vascular invasion (macroVI) is associated with poor outcomes after liver transplantation (LT) for hepatocellular carcinoma (HCC). Whether…”
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Genetic Determinants of Mouse Hepatitis Virus Strain 1 Pneumovirulence
Published in Journal of Virology (15-09-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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