Search Results - "LEVIN, Mariano J"
-
1
Proteins associated with SF3a60 in T. brucei
Published in PloS one (20-03-2014)“…Trypanosoma brucei relies on Spliced leader trans splicing to generate functional messenger RNAs. Trans splicing joins the specialized SL exon from the SL RNA…”
Get full text
Journal Article -
2
Serological based monitoring of a cohort of patients with chronic Chagas disease treated with benznidazole in a highly endemic area of northern Argentina
Published in Memórias do Instituto Oswaldo Cruz (01-06-2016)“…This study aimed to evaluate well-documented diagnostic antigens, named B13, 1F8 and JL7 recombinant proteins, as potential markers of seroconversion in…”
Get full text
Journal Article -
3
Validation of a Rapid and Reliable Test for Diagnosis of Chagas' Disease by Detection of Trypanosoma cruzi-Specific Antibodies in Blood of Donors and Patients in Central America
Published in Journal of Clinical Microbiology (01-10-2005)“…In this study we compared the performance of the Chagas Stat-Pak rapid immunochromatographic test with a standard enzyme-linked immunosorbent assay (ELISA) in…”
Get full text
Journal Article -
4
The Structure of the 80S Ribosome from Trypanosoma cruzi Reveals Unique rRNA Components
Published in Proceedings of the National Academy of Sciences - PNAS (19-07-2005)“…We present analysis, by cryo-electron microscopy and single-particle reconstruction, of the structure of the 80S ribosome from Trypanosoma cruzi, the…”
Get full text
Journal Article -
5
Selective blockade of trypanosomatid protein synthesis by a recombinant antibody anti-Trypanosoma cruzi P2β protein
Published in PloS one (03-05-2012)“…The ribosomal P proteins are located on the stalk of the ribosomal large subunit and play a critical role during the elongation step of protein synthesis. The…”
Get full text
Journal Article -
6
Antibodies against the Trypanosoma cruzi ribosomal P proteins induce apoptosis in HL-1 cardiac cells
Published in International journal for parasitology (01-05-2011)“…[Display omitted] ► The monoclonal antibody against the C-terminal end of the Trypanosoma cruzi ribosomal P2 protein (R13 peptide), called mAb 17.2, and its…”
Get full text
Journal Article -
7
Crystal structure of the complex mAb 17.2 and the C-terminal region of Trypanosoma cruzi P2β protein: implications in cross-reactivity
Published in PLoS neglected tropical diseases (01-11-2011)“…Patients with Chronic Chagas' Heart Disease possess high levels of antibodies against the carboxyl-terminal end of the ribosomal P2ß protein of Trypanosoma…”
Get full text
Journal Article -
8
An improved serodiagnostic test for Chagas' disease employing a mixture of Trypanosoma cruzi recombinant antigens
Published in Transfusion (Philadelphia, Pa.) (01-01-2003)“…BACKGROUND : Blood transfusion is one of the most important transmission routes of Chagas' disease, a major parasitic infection in Latin America. Therefore,…”
Get full text
Journal Article -
9
Differential profile and biochemical effects of antiautonomic membrane receptor antibodies in ventricular arrhythmias and sinus node dysfunction
Published in Circulation (New York, N.Y.) (03-04-2001)“…The relationship between anti-beta-adrenergic (anti-betaR) and anti-M(2)-cholinergic (anti-M2R) receptor antibodies (Abs) and cardiac arrhythmias and their…”
Get full text
Journal Article -
10
Interaction map of the Trypanosoma cruzi ribosomal P protein complex (stalk) and the elongation factor 2
Published in Journal of molecular recognition (01-03-2011)“…The large subunit of the eukaryotic ribosome possesses a long and protruding stalk formed by the ribosomal P proteins. This structure is involved in the…”
Get full text
Journal Article -
11
Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas Disease
Published in Science (American Association for the Advancement of Science) (15-07-2005)“…Whole-genome sequencing of the protozoan pathogen Trypanosoma cruzi revealed that the diploid genome contains a predicted 22,570 proteins encoded by genes, of…”
Get full text
Journal Article -
12
Direct molecular profiling of minicircle signatures and lineages of Trypanosoma cruzi bloodstream populations causing congenital Chagas disease
Published in International journal for parasitology (01-10-2007)“…Congenital transmission of Trypanosoma cruzi may occur in some or all the gestations from a T. cruzi-infected mother. Variable rates of congenital transmission…”
Get full text
Journal Article -
13
Trypanosoma cruzi I genotypes in different geographical regions and transmission cycles based on a microsatellite motif of the intergenic spacer of spliced-leader genes
Published in International journal for parasitology (01-12-2010)“…The intergenic region of spliced-leader (SL-IR) genes from 105 Trypanosoma cruzi I (Tc I) infected biological samples, culture isolates and stocks from 11…”
Get full text
Journal Article -
14
Molecular epidemiology of domestic and sylvatic Trypanosoma cruzi infection in rural northwestern Argentina
Published in International journal for parasitology (01-11-2008)“…Genetic diversity of Trypanosoma cruzi populations and parasite transmission dynamics have been well documented throughout the Americas, but few studies have…”
Get full text
Journal Article -
15
Aetiological treatment of congenital Chagas’ disease diagnosed and monitored by the polymerase chain reaction
Published in Journal of antimicrobial chemotherapy (01-09-2003)“…Objectives: This prospective study focused on the evaluation of anti-parasitic therapy in congenital Chagas’ disease, diagnosed and monitored by PCR and…”
Get full text
Journal Article -
16
-
17
Cross-talk between anti-beta(1)-adrenoceptor antibodies in dilated cardiomyopathy and Chagas' heart disease
Published in Autoimmunity (Chur, Switzerland) (01-09-2008)“…Anti-beta(1)-adrenoceptor autoantibodies, first described in sera of patients with Chagas' disease, are now well documented in patients with idiopathic dilated…”
Get full text
Journal Article -
18
-
19
Identification of core components of the exon junction complex in trypanosomes
Published in Molecular and biochemical parasitology (01-08-2009)“…In animal cells, the exon junction complex (EJC) is deposited onto mRNAs during the second step of splicing, 20–24nt upstream of the exon–exon junction. The…”
Get full text
Journal Article -
20
Evaluation of in-house ELISA using Trypanosoma cruzi lysate and recombinant antigens for diagnosis of Chagas disease and discrimination of its clinical forms
Published in The American journal of tropical medicine and hygiene (01-08-2012)“…The aim of this work was to investigate the potential usefulness of Trypanosoma cruzi lysate, recombinant protein JL7, and peptides P013, R13, JL18, JL19, and…”
Get full text
Journal Article