Search Results - "LEVERE, R"

Transfection of the Human Heme Oxygenase Gene Into Rabbit Coronary Microvessel Endothelial Cells: Protective Effect Against Heme and Hemoglobin Toxicity by Abraham, N. G., Lavrovsky, Y., Schwartzman, M. L., Stoltz, R. A., Levere, R. D., Gerritsen, M. E.

“…Heme oxygenase (HO) is a stress protein and has been suggested to participate in defense mechanisms against agents that may induce oxidative injury such as…”
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Identification of Binding Sites for Transcription Factors NF-κB and AP-2 in the Promoter Region of the Human Heme Oxygenase 1 Gene by Lavrovsky, Yan, Schwartzman, Michal L., Levere, Richard D., Kappas, Attallah, Abraham, Nader G.

“…Heme oxygenase (HO) is the rate-limiting enzyme in heme catabolism and its activity is induced by many agents, including its substrate heme, heavy metals, UV…”
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Heme oxygenase induction with attenuation of experimentally induced corneal inflammation by Laniado-Schwartzman, Michal, Abraham, Nader G., Conners, Michael, Dunn, Michael W., Levere, Richard D., Kappas, Attallah

“…Heme oxygenase (HO), by catabolizing heme to bile pigments, down-regulates cellular levels of heme and hemeproteins; certain of the latter, i.e. cytochrome…”
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Effect of heme arginate administration on blood pressure in spontaneously hypertensive rats by LEVERE, R. D, MARTASEK, P, ESCALANTE, B, SCHWARTZMAN, M. L, ABRAHAM, N. G

“…Cytochrome P450 content and activities are increased in the kidneys of spontaneously hypertensive rats (SHR) as compared with those of normotensive,…”
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Treatment with Tin Prevents the Development of Hypertension in Spontaneously Hypertensive Rats by Sacerdoti, David, Escalante, Bruno, Abraham, Nader G., McGiff, John C., Levere, Richard D., Schwartzman, Michal L.

“…Cytochrome P-450--dependent metabolites of arachidonic acid (AA) increased in the kidneys of young, spontaneously hypertensive rats (SHRs) during the period of…”
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A closed eye contact lens model of corneal inflammation. Part 2: Inhibition of cytochrome P450 arachidonic acid metabolism alleviates inflammatory sequelae by Conners, MS, Stoltz, RA, Davis, KL, Dunn, MW, Abraham, NG, Levere, RD, Laniado- Schwartzman, M

“…The authors have previously shown a marked increase in corneal epithelial arachidonic acid metabolism to 12-hydroxyeicosatetraenoic acid (12-HETE) and…”
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Tin-mediated heme oxygenase gene activation and cytochrome P450 arachidonate hydroxylase inhibition in spontaneously hypertensive rats by Da Silva, J L, Tiefenthaler, M, Park, E, Escalante, B, Schwartzman, M L, Levere, R D, Abraham, N G

“…The effect of SnCl2 on the transcription of the heme oxygenase gene in spontaneously hypertensive rats was examined using cDNA for the rat heme oxygenase…”
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Heme Inhibits Human Immunodeficiency Virus 1 Replication in Cell Cultures and Enhances the Antiviral Effect of Zidovudine by Levere, Richard D., Gong, Yi-Fei, Kappas, Attallah, Bucher, Doris J., Wormser, Gary P., Abraham, Nader G.

“…The effects of heme alone and heme administered together with 3'-azido-3'-deoxythymidine (AZT) on human immunodeficiency virus replication in human peripheral…”
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Differential induction of heme oxygenase in the hepatocarcinoma cell line (Hep3B) by environmental agents by Lutton, J D, da Silva, J L, Moqattash, S, Brown, A C, Levere, R D, Abraham, N G

“…In situ hybridization and Northern analysis of heme oxygenase (HO) mRNA was used to determine the induction and expression of HO by various environmental…”
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Cytochrome P450-dependent arachidonic acid metabolism in human kidney by Schwartzman, Michal L., Martasek, Pavel, Rios, Amelia R., Levere, Richard D., Solangi, Karim, Goodman, Alvin I., Abraham, Nader G.

“…Cytochrome P450-dependent arachidonic acid metabolism in human kidney. Cytochrome P450-dependent arachidonic acid metabolism in human kidney cortex from…”
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Hemin and L-arginine regulation of blood pressure in spontaneous hypertensive rats by Martasek, P, Schwartzman, M L, Goodman, A I, Solangi, K B, Levere, R D, Abraham, N G

“…Perturbation in heme metabolism is known to affect the level and activity of hemoproteins, including cytochrome P450-dependent arachidonic acid metabolism. The…”
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Purification and characterization of cytochrome P-450-dependent arachidonic acid epoxygenase from human liver by Laniado-Schwartzman, M, Davis, K L, McGiff, J C, Levere, R D, Abraham, N G

“…A novel human liver cytochrome P-450 isozyme (P-450-AA), which catalyzes arachidonic acid epoxidation, has been purified to electrophoretic homogeneity from…”
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Role of heme metabolism in AZT-induced bone marrow toxicity by Lutton, J D, Mathew, A, Levere, R D, Abraham, N G

“…We studied the effects of azidothymidine (AZT) on rat bone marrow heme metabolism and colony growth as determined by assays of granulocyte-macrophage (CFU-GM),…”
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Presence of Cytochrome P-450—Dependent Monooxygenase in Intimal Cells of the Hog Aorta by ABRAHAM, NADER G, PINTO, ALDO, MULLANE, KEVIN M, LEVERE, RICHARD D, SPOKAS, ERIC

“…Cytochrome P-450-dependent mixed function oxidase activity is present in vascular tissue; however, as far as we could determine, the distribution of…”
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Sensitivity of human tissue heme oxygenase to a new synthetic metalloporphyrin by Chernick, R J, Martasek, P, Levere, R D, Margreiter, R, Abraham, N G

“…Heme oxygenase, the rate-limiting enzyme for heme degradation, can be inhibited by several new synthetic metalloporphyrins. Under certain conditions, a…”
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Heme metabolism and erythropoiesis in abnormal iron states: role of delta-aminolevulinic acid synthase and heme oxygenase by Abraham, N G, Lutton, J D, Levere, R D

“…Heme metabolism was examined in bone marrow and hepatic cells from iron-deficient and chronically iron-overloaded rats. Results indicate that the rate limiting…”
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Physiologic role of heme and cytochrome P-450 in hematopoietic cells by Lutton, J D, Levere, R D, Abraham, N G

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Regulation of arachidonic acid metabolism by cytochrome P-450 in rabbit kidney by Schwartzman, M L, Abraham, N G, Carroll, M A, Levere, R D, McGiff, J C

“…Renal microsomal cytochrome P-450-dependent arachidonic acid metabolism was correlated with the level of cytochrome P-450 in the rabbit kidney. Cobalt, an…”
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Identification of heme oxygenase and cytochrome P-450 in the rabbit heart by Abraham, N G, Pinto, A, Levere, R D, Mullane, K

“…The regulation of cardiac heme oxygenase and cytochrome P-450 mixed function oxidase was studied in the rabbit heart. Heme oxygenase activity is found in…”
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Zinc Porphyrins: Potent Inhibitors of Hematopoieses in Animal and Human Bone Marrow by Lutton, John D., Abraham, Nader G., Drummond, George S., Levere, Richard D., Kappas, Attallah

“…The effects of selected heme analogues on heme oxygenase activity in tissues and on human and rabbit bone marrow hematopoietic colony growth were examined…”
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