Search Results - "LEVENTHAL, J. J"

Assessing Antibody Strength: Comparison of MFI, C1q, and Titer Information by Tambur, A. R., Herrera, N. D., Haarberg, K. M. K., Cusick, M. F., Gordon, R. A., Leventhal, J. R., Friedewald, J. J., Glotz, D.

“…The presence of donor‐specific HLA antibodies before or after transplantation may have different implications based on the antibody strength. Yet, current…”
Get full text

Near total body vitiligo secondary to immunotherapy for metastatic melanoma by Olamiju, B., Leventhal, J.S.

Get full text

Cutaneous Immune-Related Adverse Events Secondary to Immune Checkpoint Inhibitors and Their Management by Pach, J, Leventhal, J S

“…Immune checkpoint inhibitors (CPIs) are highly effective in the treatment of various cancers. Immunotherapy enhances antitumor activity by relieving inhibition…”
Get full text

Integrative analysis reveals a conserved role for the amyloid precursor protein in proteostasis during aging by Nithianandam, Vanitha, Bukhari, Hassan, Leventhal, Matthew J., Battaglia, Rachel A., Dong, Xianjun, Fraenkel, Ernest, Feany, Mel B.

“…Aβ peptides derived from the amyloid precursor protein (APP) have been strongly implicated in the pathogenesis of Alzheimer’s disease. However, the normal…”
Get full text

How Clinical Immunologists Can Impact Patient Care within a Cancer Center: A Tale of 3 Patients by Belmont, A., Leventhal, J., Price, C.

Get full text

Immune Cell‐Derived C3a and C5a Costimulate Human T Cell Alloimmunity by Cravedi, P., Leventhal, J., Lakhani, P., Ward, S. C., Donovan, M. J., Heeger, P. S.

“…Emerging evidence indicates that complement provides costimulatory signals for murine T cells but whether complement impacts human T cells remains unclear. We…”
Get full text

Pruritic reticulation: don't ‘fiddle’ around by Salam, A., Peleva, E., Cowper, S. E., Leventhal, J. S.

“…Click here for the corresponding questions to this CME article…”
Get full text

Ex Vivo‐Expanded Natural CD4+CD25+ Regulatory T Cells Synergize With Host T‐Cell Depletion to Promote Long‐Term Survival of Allografts by Xia, G., He, J., Leventhal, J. R.

“…Foxp3+CD4+CD25+ natural regulatory T (nTreg) cells have been shown in immunodeficient mice to suppress allograft rejection after adoptive cotransfer. We…”
Get full text

APOL1‐Associated End‐Stage Renal Disease in a Living Kidney Transplant Donor by Zwang, N. A., Shetty, A., Sustento‐Reodica, N., Gordon, E. J., Leventhal, J., Gallon, L., Friedewald, J. J.

“…Homozygosity for apolipoprotein‐L1 (APOL1) risk variants has emerged as an important predictor of renal disease in individuals of African descent over the past…”
Get full text

Nonchimeric HLA‐Identical Renal Transplant Tolerance: Regulatory Immunophenotypic/Genomic Biomarkers by Leventhal, J. R., Mathew, J. M., Salomon, D. R., Kurian, S. M., Friedewald, J. J., Gallon, L., Konieczna, I., Tambur, A. R., Charette, J., Levitsky, J., Jie, C., Kanwar, Y. S., Abecassis, M. M., Miller, J.

“…We previously described early results of a nonchimeric operational tolerance protocol in human leukocyte antigen (HLA)‐identical living donor renal transplants…”
Get full text

Clinical Implications of Basic Science Discoveries: Induced Pluripotent Stem Cell Therapy in Transplantation—A Potential Role for Immunologic Tolerance by Wertheim, J. A., Leventhal, J. R.

“…Induced pluripotent stem cells (iPSCs) hold the potential for future development of genetically identical tissues from almost any mature cell lineage. For…”
Get full text

Alemtuzumab Induction and Prednisone‐Free Maintenance Immunotherapy in Simultaneous Pancreas‐Kidney Transplantation Comparison With Rabbit Antithymocyte Globulin Induction – Long‐Term Results by Kaufman, D. B., Leventhal, J. R., Gallon, L. G., Parker, M. A.

“…This study compared the effects of using two T‐cell depleting antibodies, alemtuzumab (anti‐CD 52, Campath‐1H®) and rabbit antithymocyte globulin…”
Get full text

Allospecific Memory B Cell Responses Are Dependent on Autophagy by Fribourg, M., Ni, J., Nina Papavasiliou, F., Yue, Z., Heeger, P. S., Leventhal, J. S.

“…Long‐lived, donor‐reactive memory B cells (Bmems) can produce alloantibodies that mediate transplant injury. Autophagy, an intrinsic mechanism of cell…”
Get full text

Calcineurin‐Inhibitor‐Free Immunosuppression Based on the JAK Inhibitor CP‐690,550: A Pilot Study in De Novo Kidney Allograft Recipients by Busque, S., Leventhal, J., Brennan, D. C., Steinberg, S., Klintmalm, G., Shah, T., Mulgaonkar, S., Bromberg, J. S., Vincenti, F., Hariharan, S., Slakey, D., Peddi, V. R., Fisher, R. A., Lawendy, N., Wang, C., Chan, G.

“…This randomized, pilot study compared the Janus kinase inhibitor CP‐690,550 (15 mg BID [CP15] and 30 mg BID [CP30], n = 20 each) with tacrolimus (n = 21) in de…”
Get full text

Evolving Approaches of Hematopoietic Stem Cell-Based Therapies to Induce Tolerance to Organ Transplants: The Long Road to Tolerance by Leventhal, J, Miller, J, Abecassis, M, Tollerud, D J, Ildstad, S T

“…The immunoregulatory properties of hematopoietic stem cells (HSCs) have been recognized for more than 60 years, beginning in 1945, when Owen reported that…”
Get full text

BK Virus Replication and Nephropathy After Alemtuzumab‐Induced Kidney Transplantation by Theodoropoulos, N., Wang, E., Penugonda, S., Ladner, D. P., Stosor, V., Leventhal, J., Friedewald, J., Angarone, M. P., Ison, M. G.

“…BK virus nephropathy (BKVN) is a recognized cause of graft failure in kidney transplant recipients. There are limited data on the epidemiology of BK virus…”
Get full text

Recurrent genetic HLA loss in AML relapsed after matched unrelated allogeneic hematopoietic cell transplantation by Jan, Max, Leventhal, Matthew J., Morgan, Elizabeth A., Wengrod, Jordan C., Nag, Anwesha, Drinan, Samantha D., Wollison, Bruce M., Ducar, Matthew D., Thorner, Aaron R., Leppanen, Scott, Baronas, Jane, Stevens, Jonathan, Lane, William J., Kekre, Natasha, Ho, Vincent T., Koreth, John, Cutler, Corey S., Nikiforow, Sarah, Alyea, Edwin P., Antin, Joseph H., Soiffer, Robert J., Ritz, Jerome, Lindsley, R. Coleman, Ebert, Benjamin L.

“…Immune evasion is a hallmark of cancer and a central mechanism underlying acquired resistance to immune therapy. In allogeneic hematopoietic cell…”
Get full text

Perception Versus Reality?: Virtual Crossmatch—How to Overcome Some of the Technical and Logistic Limitations by Tambur, A. R., Ramon, D. S., Kaufman, D. B., Friedewald, J., Luo, X., Ho, B., Skaro, A., Caicedo, J., Ladner, D., Baker, T., Fryer, J., Gallon, L., Miller, J., Abecassis, M. M., Leventhal, J.

“…The goal of this work was to evaluate concordance between (a) actual flow cytometric crossmatch (FCXM) that is performed by the OPO laboratory servicing our…”
Get full text

Image Gallery: Juvenile autoimmune pemphigus presenting with diffuse gingival hypertrophy and antibodies against desmocollin 3 by Leventhal, J. S., Haberland, C.M., Cowper, S.E., Tomayko, M.M.

Get full text

Intergenerational continuity of child physical abuse: how good is the evidence? by Ertem, Ilgi Ozturk, Leventhal, John M, Dobbs, Sara

“…There is widespread belief that individuals who were physically abused during childhood are more likely to abuse their own children than those who were not…”
Get full text