Search Results - "LEVELL, M. J."

Interleukin‐6 and ACTH act synergistically to stimulate the release of corticosterone from adrenal gland cells by SALAS, M. A., EVANS, S. W., LEVELL, M. J., WHICHER, J. T.

“…SUMMARY We investigated whether interleukin‐6 (IL‐6) could cause the release of corticosterone by a direct interaction with the adrenal gland. Primary cultures…”
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Inhibition of testicular 17 alpha-hydroxylase and 17,20-lyase but not 3 beta-hydroxysteroid dehydrogenase-isomerase or 17 beta-hydroxysteroid oxidoreductase by ketoconazole and other imidazole drugs by Ayub, M, Levell, M J

“…Ketoconazole, an orally active antifungal drug, is known to inhibit testicular androgen production both in vitro and in vivo. The aim of the present study was…”
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Structure-activity relationships of the inhibition of human placental aromatase by imidazole drugs including ketoconazole by Ayub, M, Levell, M J

“…The aim of the present study was to investigate the effectiveness of several imidazole drugs to inhibit human placental aromatase compared with the known…”
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Suppression of plasma androgens by the antiandrogen flutamide in prostatic cancer patients treated with Zoladex, a GnRH analogue by Ayub, M, Levell, M J

“…Chronic treatment with the GnRH (gonadotrophin hormone releasing hormone) agonist Zoladex causes suppression of testicular androgens. Use of antiandrogens has…”
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Acne is not associated with abnormal plasma androgens by Levell, M J, Cawood, M L, Burke, B, Cunliffe, W J

“…Plasma dehydroepiandrosterone sulphate, androstenedione, testosterone (T), dihydrotestosterone (DHT), and sex hormone binding globulin (SHBG) have been…”
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The inhibition of human prostatic aromatase activity by imidazole drugs including ketoconazole and 4-hydroxyandrostenedione by Ayub, M, Levell, M J

“…Ketoconazole, an orally active imidazole drug and bifonazole, clotrimazole, econazole, isoconazole, miconazole and tioconazole are known as inhibitors of…”
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Arginine vasopressin in manic-depressive psychosis by Penney, M D, Levell, M J, Hullin, R P

“…Urinary excretions of arginine vasopressin (AVP), sodium, potassium, osmoles and creatinine were measured in three in-patients with bipolar manic-depressive…”
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Relationship of testosterone, sex hormone binding globulin, and calculated free testosterone to subsequent clinical progress in patients with carcinoma of the prostate treated with bilateral orchidectomy or estrogens by Levell, M J, Siddall, J K, Rowe, E, Glashan, R W, Robinson, M R, Pidcock, N B

“…The concentration in serum of testosterone, sex hormone binding globulin (SHBG), and albumin has been measured, and from these measurements free testosterone…”
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Inhibition of human adrenal steroidogenic enzymes in vitro by imidazole drugs including ketoconazole by Ayub, M, Levell, M J

“…The effect of several imidazole containing drugs including keto on human adrenal 17 alpha-hydroxylase, 17,20-lyase, 21-hydroxylase, 11 beta-hydroxylase and 3…”
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Inhibition of rat testicular 17 alpha-hydroxylase and 17,20-lyase activities by anti-androgens (flutamide, hydroxyflutamide, RU23908, cyproterone acetate) in vitro by Ayub, M, Levell, M J

“…Flutamide, hydroxyflutamide, RU23908 and cyproterone acetate (CPA) inhibited rat testicular microsomal 17 alpha-hydroxylase and 17,20-lyase activities in…”
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Variation of cortisol metabolism as a contributing factor to discrepancies in the measurement of cortisol production rate by Levell, M J

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Effects of analytical error on the clinical discrimination of the urinary 11-hydroxycorticosteroid assay by Levell, M J

“…A model consisting of overlapping Gaussian distributions of disease and reference values has been used to calculate the effects of analytical imprecision on…”
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Measurement of sex hormone binding globulin by Pidcock, N B, Levell, M J

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Inhibition of aldosterone production in adrenal cell suspensions by serum from patients with manic-depressive psychosis by O'Brien, M J, Levell, M J, Hullin, R P

“…A method of preparing a suspension of cells of the zona glomerulosa from rat adrenal capsules treated with crude collagenase is described. The cells responded…”
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Redefinition of the normal range for serum sodium by Payne, R B, Levell, M J

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Comparison of immunodiffusion and DHT-binding methods for the measurement of sex hormone binding globulin in plasma and serum by Earnshaw, R J, Bowen, M, Levell, M J

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Aldosterone production rates in manic-depressive psychosis by Allsopp, M N, Levell, M J, Stitch, S R, Hullin, R P

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Impairment of the pituitary-adrenal axis following prolonged therapy with corticotrophin by Levell, M J, Noronha, M J, Stitch, S R

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The assessment of adrenal-cortical function in patients receiving corticotrophin therapy by Levell, M J, Stitch, S R, Noronha, M, Vas, C

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Inhibition of in vitro production of aldosterone by manic-depressive sera by Hullin, R P, Levell, M J, O'Brien, M J, Toumba, K J

“…Serum samples from psychiatric patients were added to incubations of rat adrenal cortical cells synthesizing aldosterone. A high proportion of sera from…”
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