Search Results - "LEV, Dina C"

Outcome Prediction in Primary Resected Retroperitoneal Soft Tissue Sarcoma: Histology-Specific Overall Survival and Disease-Free Survival Nomograms Built on Major Sarcoma Center Data Sets by GRONCHI, Alessandro, MICELI, Rosalba, BONVALOT, Sylvie, MARIANI, Luigi, POLLOCK, Raphael E, SHURELL, Elizabeth, EILBER, Fritz C, EILBER, Frederick R, ANAYA, Daniel A, KATTAN, Michael W, HONORE, Charles, LEV, Dina C, COLOMBO, Chiara

“…Integration of numerous prognostic variables not included in the conventional staging of retroperitoneal soft tissue sarcomas (RPS) is essential in providing…”
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Multimodality Treatment of Desmoplastic Small Round Cell Tumor: Chemotherapy and Complete Cytoreductive Surgery Improve Patient Survival by Subbiah, Vivek, Lamhamedi-Cherradi, Salah-Eddine, Cuglievan, Branko, Menegaz, Brian A, Camacho, Pamela, Huh, Winston, Ramamoorthy, Vandhana, Anderson, Pete M, Pollock, Raphael E, Lev, Dina C, Qiao, Wei, McAleer, Mary Frances, Benjamin, Robert S, Patel, Shreyaskumar, Herzog, Cynthia E, Daw, Najat C, Feig, Barry W, Lazar, Alexander J, Hayes-Jordan, Andrea, Ludwig, Joseph A

“…Desmoplastic small round cell tumor (DSRCT), which harbors EWSR1-WT1 t(11;22)(p13:q12) chromosomal translocation, is an aggressive malignancy that typically…”
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ERG and FLI1 protein expression in epithelioid sarcoma by Stockman, David L, Hornick, Jason L, Deavers, Michael T, Lev, Dina C, Lazar, Alexander J, Wang, Wei-Lien

“…Epithelioid sarcoma is a rare, aggressive keratin-positive sarcoma that co-expresses CD34 in 50% of cases and may mimic an angiosarcoma. Recently, we have…”
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Detection and characterization of EWSR1/ATF1 and EWSR1/CREB1 chimeric transcripts in clear cell sarcoma (melanoma of soft parts) by Wang, Wei-Lien, Mayordomo, Empar, Zhang, Wenyong, Hernandez, Vivian S, Tuvin, Daniel, Garcia, Lisa, Lev, Dina C, Lazar, Alexander JF, López-Terrada, Dolores

“…Unlike melanoma, clear cell sarcoma harbors either a t(12;22)(q13;q12) recurrent translocation, resulting in an EWSR1/ATF1 chimeric gene, or less commonly a…”
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The role of surgical margin status in retroperitoneal sarcoma by Anaya, Daniel A., Lev, Dina C., Pollock, Raphael E.

“…Retroperitoneal sarcomas (RPS) represent approximately 15% of all soft tissue sarcomas (STS). Clinical and prognostic features as well as oncologic outcomes…”
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Genomic and molecular characterization of malignant peripheral nerve sheath tumor identifies the IGF1R pathway as a primary target for treatment by Yang, Jilong, Ylipää, Antti, Sun, Yan, Zheng, Hong, Chen, Kexin, Nykter, Matti, Trent, Jonathan, Ratner, Nancy, Lev, Dina C, Zhang, Wei

“…Malignant peripheral nerve sheath tumor (MPNST) is a rare sarcoma that lacks effective therapeutic strategies. We gain insight into the most recurrent…”
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A Small-Molecule Inhibitor Targeting the Mitotic Spindle Checkpoint Impairs the Growth of Uterine Leiomyosarcoma by WEIWEI SHAN, AKINFENWA, Patricia Y, SAVANNAH, Kari B, KOLOMEYEVSKAYA, Nonna, LAUCIRICA, Rudolfo, THOMAS, Dafydd G, ODUNSI, Kunle, CREIGHTON, Chad J, LEV, Dina C, ANDERSON, Matthew L

“…Uterine leiomyosarcoma (ULMS) is a poorly understood cancer with few effective treatments. This study explores the molecular events involved in ULMS with the…”
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Vascular tumors have increased p70 S6-kinase activation and are inhibited by topical rapamycin by Du, Wa, Gerald, Damien, Perruzzi, Carole A, Rodriguez-Waitkus, Paul, Enayati, Ladan, Krishnan, Bhuvaneswari, Edmonds, Joseph, Hochman, Marcelo L, Lev, Dina C, Phung, Thuy L

“…Vascular tumors are endothelial cell neoplasms whose cellular and molecular mechanisms, leading to tumor formation, are poorly understood, and current…”
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Computed tomography scan‐driven selection of treatment for retroperitoneal liposarcoma histologic subtypes by Lahat, Guy, Madewell, John E., Anaya, Daniel A., Qiao, Wei, Tuvin, Daniel, Benjamin, Robert S., Lev, Dina C., Pollock, Ralphael E.

“…BACKGROUND: Well differentiated (WD) and dedifferentiated (DD) retroperitoneal liposarcoma (RPLS) have distinct biologic behaviors. Consequently, the…”
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Detection of myxoid liposarcoma-associated FUS–DDIT3 rearrangement variants including a newly identified breakpoint using an optimized RT-PCR assay by Powers, Martin P, Wang, Wei-Lien, Hernandez, Vivian S, Patel, Kayuri S, Lev, Dina C, Lazar, Alexander J, López-Terrada, Dolores H

“…Myxoid/round cell liposarcoma is characterized by the recurrent translocations t(12;16)(q13;p11) and, less commonly, t(12;22)(q13;q12), which fuse FUS or EWSR1…”
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The hepatocyte growth factor receptor as a potential therapeutic target for dedifferentiated liposarcoma by Bill, Kate Lynn J, Garnett, Jeannine, Ma, Xiaoyan, May, Caitlin D, Bolshakov, Svetlana, Lazar, Alexander J, Lev, Dina C, Pollock, Raphael E

“…Dedifferentiated liposarcomas (DDLPS) are highly resistant to conventional chemo- and radiotherapies, with surgical resection remaining the classic treatment…”
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Analysis of the Intratumoral Adaptive Immune Response in Well Differentiated and Dedifferentiated Retroperitoneal Liposarcoma by Tseng, William W., Malu, Shruti, Zhang, Minying, Chen, Jieqing, Sim, Geok Choo, Wei, Wei, Ingram, Davis, Somaiah, Neeta, Lev, Dina C., Pollock, Raphael E., Lizée, Gregory, Radvanyi, Laszlo, Hwu, Patrick

“…Treatment options are limited in well differentiated (WD) and dedifferentiated (DD) retroperitoneal liposarcoma. We sought to study the intratumoral adaptive…”
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Combining PCI-24781, a Novel Histone Deacetylase Inhibitor, with Chemotherapy for the Treatment of Soft Tissue Sarcoma by Lopez, Gonzalo, Liu, Juehui, Ren, Wenhong, Wei, Wei, Wang, Suizhao, Lahat, Guy, Zhu, Quan-Sheng, Bornmann, William G, McConkey, David J, Pollock, Raphael E, Lev, Dina C

“…Purpose: Histone deactylase inhibitors (HDACi) are a promising new class of anticancer therapeutics; however, little is known about HDACi activity in soft…”
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Establishing Prognosis in Retroperitoneal Sarcoma: A New Histology-Based Paradigm by Anaya, Daniel A., Lahat, Guy, Wang, Xuemei, Xiao, Lianchun, Tuvin, Daniel, Pisters, Peter W., Lev, Dina C., Pollock, Raphael E.

“…Background Retroperitoneal sarcoma (RPS) American Joint Committee on Cancer (AJCC) staging applies to primary tumors only; due to specific RPS disease…”
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The role of chemotherapy in advanced solitary fibrous tumors: a retrospective analysis by Park, Min S, Ravi, Vinod, Conley, Anthony, Patel, Shreyaskumar R, Trent, Jonathan C, Lev, Dina C, Lazar, Alexander J, Wang, Wei-Lien, Benjamin, Robert S, Araujo, Dejka M

“…Patients with advanced solitary fibrous tumors (SFTs) have a poor prognosis; treatment options for recurrent disease are particularly limited. Several novel…”
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preclinical model for predicting drug response in soft-tissue sarcoma with targeted AAVP molecular imaging by Hajitou, Amin, Lev, Dina C, Hannay, Jonathan A.F, Korchin, Borys, Staquicini, Fernanda I, Soghomonyan, Suren, Alauddin, Mian M, Benjamin, Robert S, Pollock, Raphael E, Gelovani, Juri G, Pasqualini, Renata, Arap, Wadih

“…Human sarcomas are rare but diverse malignant tumors derived from mesenchymal tissue. Clinical response to therapy is currently determined by the modified…”
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IFN Regulatory Factor 8 Mediates Apoptosis in Nonhemopoietic Tumor Cells via Regulation of Fas Expression by Yang, Dafeng, Thangaraju, Muthusamy, Browning, Darren D, Dong, Zheng, Korchin, Borys, Lev, Dina C, Ganapathy, Vadivel, Liu, Kebin

“…IFN regulatory factor 8 (IRF8) is a transcription factor that was originally identified in myeloid cells and has been shown to be essential for differentiation…”
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MicroRNA-16 suppresses metastasis in an orthotopic, but not autochthonous, mouse model of soft tissue sarcoma by Sachdeva, Mohit, Whitley, Melody J, Mito, Jeffrey K, Ma, Yan, Lev, Dina C, Cardona, Diana M, Kirsch, David G

“…MicroRNAs (miRNAs) can regulate tumor cell invasion and metastasis in a tumor-specific manner. We recently demonstrated that global downregulation of miRNAs…”
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MicroRNA-16 suppresses metastasis in an orthotopic, but not autochthonous, mouse model of soft tissue sarcoma by Sachdeva, Mohit, Whitley, Melodi J, Mito, Jeffrey K, Ma, Yan, Lev, Dina C, Cardona, Diana M, Kirsch, David G

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Locoregional Disease Patterns in Well-Differentiated and Dedifferentiated Retroperitoneal Liposarcoma: Implications for the Extent of Resection? by Tseng, William W., Madewell, John E., Wei, Wei, Somaiah, Neeta, Lazar, Alexander J., Ghadimi, Markus P., Hoffman, Aviad, Pisters, Peter W. T., Lev, Dina C., Pollock, Raphael E.

“…Background Well-differentiated (WD)/dedifferentiated (DD) liposarcoma is the most common soft tissue sarcoma of the retroperitoneum. The frequency of distant…”
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