Search Results - "LEUNG, Amy"

Onychomycosis: An Updated Review by Leung, Alexander K C, Lam, Joseph M, Leong, Kin F, Hon, Kam L, Barankin, Benjamin, Leung, Amy A M, Wong, Alex H C

“…Onychomycosis is a common fungal infection of the nail. The study aimed to provide an update on the evaluation, diagnosis, and treatment of onychomycosis. A…”
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Giardiasis: An Overview by Leung, Alexander K C, Leung, Amy A M, Wong, Alex H C, Sergi, Consolato M, Kam, Joseph K M

“…Giardiasis is an important cause of waterborne and foodborne diarrhea, daycare center outbreaks, and traveler's diarrhea. The study aimed to provide an update…”
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Novel Long Noncoding RNAs Are Regulated by Angiotensin II in Vascular Smooth Muscle Cells by Leung, Amy, Trac, Candi, Jin, Wen, Lanting, Linda, Akbany, Asad, Sætrom, Pål, Schones, Dustin E, Natarajan, Rama

“…RATIONALE:Misregulation of angiotensin II (Ang II) actions can lead to atherosclerosis and hypertension. Evaluating transcriptomic responses to Ang II in…”
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Breath-Holding Spells in Pediatrics: A Narrative Review of the Current Evidence by Leung, Alexander K C, Leung, Amy A M, Wong, Alex H C, Hon, Kam Lun

“…Breath-holding spells are common, frightening, but fortunately benign events. Familiarity with this condition is important so that an accurate diagnosis can be…”
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Regulation of angiotensin II actions by enhancers and super-enhancers in vascular smooth muscle cells by Das, Sadhan, Senapati, Parijat, Chen, Zhuo, Reddy, Marpadga A., Ganguly, Rituparna, Lanting, Linda, Mandi, Varun, Bansal, Anita, Leung, Amy, Zhang, Selena, Jia, Ye, Wu, Xiwei, Schones, Dustin E., Natarajan, Rama

“…Angiotensin II (AngII) promotes hypertension and atherosclerosis by activating growth-promoting and pro-inflammatory gene expression in vascular smooth muscle…”
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The core autophagy protein ATG4B is a potential biomarker and therapeutic target in CML stem/progenitor cells by Rothe, Katharina, Lin, Hanyang, Kevin Lin, B.L., Leung, Amy, Wang, Hui Mi, Malekesmaeili, Mehrnoush, Brinkman, Ryan R., Forrest, Donna L., Gorski, Sharon M., Jiang, Xiaoyan

“…Previous studies demonstrated that imatinib mesylate (IM) induces autophagy in chronic myeloid leukemia (CML) and that this process is critical to cell…”
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Clinical assessment of head orientation profile development and its relationship with positional plagiocephaly in healthy term infants — A prospective study by Leung, Amy Y.F, Mandrusiak, Allison, Watter, Pauline, Gavranich, John, Johnston, Leanne M

“…Abstract Background Positional plagiocephaly refers to atypical development of an uneven head shape with asymmetrical head orientation as a post-natal risk…”
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Functional Long Non-coding RNAs in Vascular Smooth Muscle Cells by Leung, Amy, Stapleton, Kenneth, Natarajan, Rama

“…Increasing evidence shows that long non-coding RNAs (lncRNAs) are not "transcriptional noise" but function in a myriad of biological processes. As such, this…”
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Induced Pluripotent Stem Cells and Genome-Editing Tools in Determining Gene Function and Therapy for Inherited Retinal Disorders by Benati, Daniela, Leung, Amy, Perdigao, Pedro, Toulis, Vasileios, van der Spuy, Jacqueline, Recchia, Alessandra

“…Inherited retinal disorders (IRDs) affect millions of people worldwide and are a major cause of irreversible blindness. Therapies based on drugs, gene…”
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Autophagy Inhibition Augments the Anticancer Effects of Epirubicin Treatment in Anthracycline-Sensitive and -Resistant Triple-Negative Breast Cancer by CHITTARANJAN, Suganthi, BORTNIK, Svetlana, YAPP, Donald T, BALLY, Marcel B, GORSKI, Sharon M, DRAGOWSKA, Wieslawa H, JING XU, ABEYSUNDARA, Namal, LEUNG, Amy, GO, Nancy E, DEVORKIN, Lindsay, WEPPLER, Sherry A, GELMON, Karen

“…Triple-negative breast cancers (TNBC) are defined by a lack of expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth…”
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Long-Read Sequencing with Hierarchical Clustering for Antiretroviral Resistance Profiling of Mixed Human Immunodeficiency Virus Quasispecies by Ng, Timothy Ting-Leung, Su, Junhao, Lao, Hiu-Yin, Lui, Wui-Wang, Chan, Chloe Toi-Mei, Leung, Amy Wing-Sze, Jim, Stephanie Hoi-Ching, Lee, Lam-Kwong, Shehzad, Sheeba, Tam, Kingsley King-Gee, Leung, Kenneth Siu-Sing, Tang, Forrest, Yam, Wing-Cheong, Luo, Ruibang, Siu, Gilman Kit-Hang

“…Abstract Background HIV infections often develop drug resistance mutations (DRMs), which can increase the risk of virological failure. However, it has been…”
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Sustainability of Clinical Benefits Gained During a Multidisciplinary Diabetes Shared Medical Appointment After Patients Return to Usual Care by Leung, Amy K, Buckley, Kelsey, Kurtz, Julie

“…This study examined whether clinical benefits gained while participating in interdisciplinary diabetes shared medical appointments (SMAs) of finite duration…”
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Evaluation of Mycobacterium tuberculosis enrichment in metagenomic samples using ONT adaptive sequencing and amplicon sequencing for identification and variant calling by Su, Junhao, Lui, Wui Wang, Lee, YanLam, Zheng, Zhenxian, Siu, Gilman Kit-Hang, Ng, Timothy Ting-Leung, Zhang, Tong, Lam, Tommy Tsan-Yuk, Lao, Hiu-Yin, Yam, Wing-Cheong, Tam, Kingsley King-Gee, Leung, Kenneth Siu-Sing, Lam, Tak-Wah, Leung, Amy Wing-Sze, Luo, Ruibang

“…Sensitive detection of Mycobacterium tuberculosis (TB) in small percentages in metagenomic samples is essential for microbial classification and drug…”
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Applications and potentials of nanopore sequencing in the (epi)genome and (epi)transcriptome era by Xie, Shangqian, Leung, Amy Wing-Sze, Zheng, Zhenxian, Zhang, Dake, Xiao, Chuanle, Luo, Ruibang, Luo, Ming, Zhang, Shoudong

“…The Human Genome Project opened an era of (epi)genomic research, and also provided a platform for the development of new sequencing technologies. During and…”
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Retinal Organoids from an AIPL1 CRISPR/Cas9 Knockout Cell Line Successfully Recapitulate the Molecular Features of LCA4 Disease by Perdigão, Pedro R L, Ollington, Bethany, Sai, Hali, Leung, Amy, Sacristan-Reviriego, Almudena, van der Spuy, Jacqueline

“…Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) is expressed in photoreceptors where it facilitates the assembly of phosphodiesterase 6 (PDE6)…”
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Mutation Spectrum Comparison between Benign Breast Lesion Cohort, Unselected Cancer Cohort and High-Risk Breast Cancer Cohort by Kwong, Ava, Ho, Cecilia Y S, Leung, Henry C M, Leung, Amy W S, Au, Chun-Hang, Ma, Edmond S K

“…Mutation study for high-risk breast and ovarian cancer (HBOC) has been extensively studied in patients of different ethnicities. Here we compared the germline…”
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Urinary Tract Infection in Children by Leung, Alexander K C, Wong, Alex H C, Leung, Amy A M, Hon, Kam L

“…Urinary Tract Infection (UTI) is a common infection in children. Prompt diagnosis and appropriate treatment are very important to reduce the morbidity…”
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Notch and Aryl Hydrocarbon Receptor Signaling Impact Definitive Hematopoiesis from Human Pluripotent Stem Cells by Leung, Amy, Zulick, Elizabeth, Skvir, Nicholas, Vanuytsel, Kim, Morrison, Tasha A., Naing, Zaw Htut, Wang, Zhongyan, Dai, Yan, Chui, David H. K., Steinberg, Martin H., Sherr, David H., Murphy, George J.

“…Induced pluripotent stem cells (iPSCs) stand to revolutionize the way we study human development, model disease, and eventually, treat patients. However, these…”
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Inhibition of DNMT1 methyltransferase activity via glucose-regulated O -GlcNAcylation alters the epigenome by Shin, Heon, Leung, Amy, Costello, Kevin R, Senapati, Parijat, Kato, Hiroyuki, Moore, Roger E, Lee, Michael, Lin, Dimitri, Tang, Xiaofang, Pirrotte, Patrick, Bouman Chen, Zhen, Schones, Dustin E

“…The DNA methyltransferase activity of DNMT1 is vital for genomic maintenance of DNA methylation. We report here that DNMT1 function is regulated by…”
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The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation by Smith, Brenden W., Rozelle, Sarah S., Leung, Amy, Ubellacker, Jessalyn, Parks, Ashley, Nah, Shirley K., French, Deborah, Gadue, Paul, Monti, Stefano, Chui, David H.K., Steinberg, Martin H., Frelinger, Andrew L., Michelson, Alan D., Theberge, Roger, McComb, Mark E., Costello, Catherine E., Kotton, Darrell N., Mostoslavsky, Gustavo, Sherr, David H., Murphy, George J.

“…The evolutionarily conserved aryl hydrocarbon receptor (AhR) has been studied for its role in environmental chemical-induced toxicity. However, recent studies…”
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