Search Results - "LEU, R. W"

Nitric oxide production by tumor targets in response to TNF: paradoxical correlation with susceptibility to TNF-mediated cytotoxicity without direct involvement in the cytotoxic mechanism by Fast, D J, Lynch, R C, Leu, R W

“…Tumor necrosis factor (TNF) is selectively cytotoxic for some tumor cells in vivo and in vitro. We determined whether TNF-mediated cytotoxicity for…”
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Kinetics of the biosynthesis of complement subcomponent C1q by murine macrophages: LPS, immune complexes, and zymosan alone and in combination with interferon-gamma by Zhou, A Q, Herriott, M J, Leu, R W

“…We investigated the effects of bacterial lipopolysaccharide (LPS), immune complexes (IC), and C3b opsonized zymosan (AZ) alone and in combination with…”
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Tumor target-derived soluble factor synergizes with IFN-gamma and IL-2 to activate macrophages for tumor necrosis factor and nitric oxide production to mediate cytotoxicity of the same target by Jiang, H, Stewart, CA, Fast, DJ, Leu, RW

“…Inflammatory mouse peritoneal macrophages were activated by IFN-gamma in synergy with IL-2 or Lipid A to mediate TNF production for autocrine generation of…”
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Staphylococcal exotoxins stimulate nitric oxide-dependent murine macrophage tumoricidal activity by FAST, D. J, SHANNON, B. J, HERRIOTT, M. J, KENNEDY, M. J, RUMMAGE, J. A, LEU, R. W

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Regulation of macrophage Fc receptor expression and phagocytosis by histidine-rich glycoprotein by CHANG, N.-S, LEU, R. W, RUMMAGE, J. A, ANDERSON, J. K, MOLE, J. E

“…Regulation of macrophage Fc receptor (Fc gamma R)-mediated phagocytic function by histidine-rich glycoprotein (HRG) was investigated. Pretreatment of…”
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Role of N-terminal domain of histidine-rich glycoprotein in modulation of macrophage Fcγ receptor-mediated phagocytosis by CHANG, N.-S, LEU, R. W, ANDERSON, J. K, MOLE, J. E

“…A brief exposure of murine peritoneal inflammatory macrophages to plasma histidine-rich glycoprotein (HRG; 77,000-81,000 MW) for 1-2 hr increased Fc gamma…”
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Mechanistic differences between migration inhibitory factor (MIF) and IFN-gamma for macrophage activation. MIF and IFN-gamma synergize with lipid A to mediate migration inhibition but only IFN-gamma induces production of TNF-alpha and nitric oxide by Herriott, MJ, Jiang, H, Stewart, CA, Fast, DJ, Leu, RW

“…Previously we found that murine macrophage migration inhibition (MMI) was mediated by IFN-gamma-priming and lipid A triggering. With the recent availability of…”
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IFN-gamma differentially modulates the susceptibility of L1210 and P815 tumor targets for macrophage-mediated cytotoxicity. Role of macrophage- target interaction coupled to nitric oxide generation, but independent of tumor necrosis factor production by Leu, RW, Leu, NR, Shannon, BJ, Fast, DJ

“…IFN-gamma primes murine macrophages to render them responsive for triggering by subactivating concentrations of bacterial LPS to mediate nonspecific tumor…”
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Regulation of Complement Functional Efficiency by Histidine-Rich Glycoprotein by Chang, Nan-Shan, Leu, Richard W., Rummage, John A., Anderson, Jacqueline K., E. Mole, I John

“…The modulation of complement functional efficiency by serum histidine-rich glycoprotein (HRG) was investigated. Addition of exogenous HRG to prewarmed diluted…”
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Characterization of C1 inhibitor binding to neutrophils by CHANG, N.-S, BOACKLE, R. J, LEU, R. W

“…In a previous study we have isolated neutrophil membrane proteins that non-covalently bind to native C1-INH (105,000 MW) and a non-functional, degraded C1-INH…”
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Effects of inhibitors of C1q biosynthesis on macrophage Fc receptor subclass-mediated antibody-dependent cellular cytotoxicity and phagocytosis by Mocharla, R, Mocharla, H, Leu, R W

“…We examined the effects of the inhibitors of C1q or collagen biosynthesis, 2,2'-dipyridyl (DP), and 3,4-dehydro-DL-proline (DHP) on murine macrophage (M phi)…”
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Triggering of interferon gamma-primed macrophages by various known complement activators for nonspecific tumor cytotoxicity by Leu, R W, Herriott, M J

“…Five known complement activators were evaluated for their capacity to directly activate murine macrophages and to trigger activation of lymphokine primed…”
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Inhibitors of C1q biosynthesis suppress activation of murine macrophages for both antibody-independent and antibody-dependent tumor cytotoxicity by Leu, RW, Zhou, AQ, Shannon, BJ, Herriott, MJ

“…The inhibitors of C1q biosynthesis and secretion, 3,4-dehydro-DL-proline (DHP) and 2,2'-dipyridyl, were previously shown to suppress murine macrophage…”
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Reconstitution of a deficiency of AKR mouse macrophages for their response to lipid A activation for tumor cytotoxicity by complement subcomponent C1q: role of IFN-gamma by Leu, RW, Zhou, AQ, Rummage, J, Fast, DJ, Shannon, BJ

“…C5-deficient AKR mouse macrophages were initially found to be refractory to activation by lipid A to mediate tumor cytotoxicity for P815 mastocytoma or L1210…”
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Inhibitor of C1q secretion suppresses the macrophage response to lipid A for nitric oxide but not for TNF production: evidence for a role of C1q in autocrine binding of TNF by Leu, R W, Stewart, C A, Herriott, M J, Fast, D J, Rummage, J A

“…Studies were designed to further define the modulatory role of complement subcomponent C1q in macrophage activation by Lipid A to mediate production of TNF and…”
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Exogenous C1q reconstitutes resident but not inflammatory mouse peritoneal macrophages for Fc receptor-dependent cellular cytotoxicity and phagocytosis. Relationship to endogenous C1q availability by Leu, RW, Zhou, AQ, Rummage, JA, Kennedy, MJ, Shannon, BJ

“…Murine resident peritoneal macrophages (PM) were refractory to activation for antibody-dependent cellular cytotoxicity (ADCC) of SRBC targets as compared with…”
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Exogenous C1q reconstitutes a secondary deficiency of C5-deficient AKR mouse macrophages for FcR-dependent cellular cytotoxicity and phagocytosis by Leu, RW, Zhou, AQ, Kennedy, MJ, Shannon, BJ

“…Studies originally designed to assess the putative role of endogenous C5 in macrophage activation for antibody-dependent cellular cytotoxicity (ADCC) yielded…”
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Reconstitution of murine resident peritoneal macrophages for antibody-dependent cellular cytotoxicity by homologous serum Clq by Leu, R W, Kriet, D, Zhou, A, Herriott, M J, Rummage, J A, Shannon, B J

“…Mouse resident peritoneal macrophages (PM) were reconstituted in their response to activation for antibody-dependent cellular cytotoxicity (ADCC) for sheep…”
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Activation of mouse macrophages for migration inhibition and for tumor cytotoxicity is mediated by interferon-gamma priming and triggering by various agents by Herriott, M J, Leu, R W

“…The requirements for activation of C3HeB/FeJ mouse peritoneal macrophages to mediate migration inhibition from capillary tubes was compared with those…”
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Tumor-derived recognition factor (TDRF) induces production of TNF-α by murine macrophages, but requires synergy with IFN-γ alone or in combination with IL-2 to induce nitric oxide synthase by Jiang, Hong, Stewart, Charles A., Fast, David J., Leu, Richard W.

“…A constitutively produced soluble activity, designated tumor-derived recognition factor (TDRF), from L1210, P815 and EL4 tumor targets, was previously shown to…”
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