Search Results - "LESNIAK, JACOB"

Safety and efficacy of anti-PD-L1 therapy in the woodchuck model of HBV infection by Balsitis, Scott, Gali, Volodymyr, Mason, Pamela J, Chaniewski, Susan, Levine, Steven M, Wichroski, Michael J, Feulner, Michael, Song, Yunling, Granaldi, Karen, Loy, James K, Thompson, Chris M, Lesniak, Jacob A, Brockus, Catherine, Kishnani, Narendra, Menne, Stephan, Cockett, Mark I, Iyer, Renuka, Mason, Stephen W, Tenney, Daniel J

“…Immune clearance of Hepatitis B virus (HBV) is characterized by broad and robust antiviral T cell responses, while virus-specific T cells in chronic hepatitis…”
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Structural and functional features of the Escherichia coli hydroperoxide resistance protein OsmC by Lesniak, Jacob, Barton, William A., Nikolov, Dimitar B.

“…The osmotically inducible protein OsmC, like its better‐characterized homolog, the organic hydroperoxide protein Ohr, is involved in defense against oxidative…”
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Structure of the Semaphorin-3A Receptor Binding Module by Antipenko, Alexander, Himanen, Juha-Pekka, van Leyen, Klaus, Nardi-Dei, Vincenzo, Lesniak, Jacob, Barton, William A., Rajashankar, Kanagalaghatta R., Lu, Min, Hoemme, Claudia, Püschel, Andreas W., Nikolov, Dimitar B.

“…The semaphorins are a large group of extracellular proteins involved in a variety of processes during development, including neuronal migration and axon…”
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Tg.rasH2 Mouse Model for Assessing Carcinogenic Potential of Pharmaceuticals: Industry Survey of Current Practices by Bogdanffy, Matthew S., Lesniak, Jacob, Mangipudy, Raja, Sistare, Frank D., Colman, Karyn, Garcia-Tapia, David, Monticello, Thomas, Blanset, Diann

“…The Tg.rasH2 mouse was developed as an alternative model to the traditional 2-year mouse bioassay for pharmaceutical carcinogenicity testing. This model has…”
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Identification of X-DING-CD4, a new member of human DING protein family that is secreted by HIV-1 resistant CD4 + T cells and has anti-viral activity by Lesner, Adam, Shilpi, Rasheda, Ivanova, Anna, Gawinowicz, Mary Ann, Lesniak, Jacob, Nikolov, Dimitar, Simm, Malgorzata

“…We reported previously the anti-viral activity named HRF (HIV-1 Resistance Factor) secreted by HIV-1 resistant cells. This work describes the identification of…”
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Identification of X-DING-CD4, a new member of human DING protein family that is secreted by HIV-1 resistant CD4+ T cells and has antiviral activity by Lesner, Adam, Shilpi, Rasheda, Ivanova, Anna, Gawinowicz, Mary Ann, Lesniak, Jacob, Nikolov, Dimitar, Simm, Malgorzata

“…We reported previously the antiviral activity named HRF (HIV-1 Resistance Factor) secreted by HIV-1 resistant cells. This work describes the identification of…”
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Structural and functional characterization of the Pseudomonas hydroperoxide resistance protein Ohr by Lesniak, Jacob, Barton, William A., Nikolov, Dimitar B.

“…Bacteria have developed complex strategies to detoxify and repair damage caused by reactive oxygen species. These compounds, produced during bacterial aerobic…”
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Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization by Thorson, Jon S, Nikolov, Dimitar B, Barton, William A, Lesniak, Jacob, Biggins, John B, Jeffrey, Philip D, Jiang, Jiqing, Rajashankar, K. R

“…Metabolite glycosylation is affected by three classes of enzymes: nucleotidylyltransferases, which activate sugars as nucleotide diphospho-derivatives,…”
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Substrate Specificity of NovM:  Implications for Novobiocin Biosynthesis and Glycorandomization by Albermann, Christoph, Soriano, Aileen, Jiang, Jiqing, Vollmer, Heidi, Biggins, John B, Barton, William A, Lesniak, Jacob, Nikolov, Dimitar B, Thorson, Jon S

“…In an effort to expand the scope of natural product in vitro glycorandomization (IVG), the substrate specificity of NovM was investigated. A test of four…”
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Structural and functional characterization of Pseudomonas aeruginosa Ohr and Escherichia coli OsmC organic hydroperoxide resistance proteins by Lesniak, Jacob A

“…Bacteria developed complex strategies to detoxify reactive oxygen species and to repair the damage caused by them. Reactive oxygen species produce cytotoxic…”
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The Effects of Lead on PKC Isoforms by COPPI, ALDO A., LESNIAK, JACOB, ZIEBA, DIANE, SCHANNE, FRANCIS A. X.

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