Search Results - "LERNER, HARVEY"
-
1
Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites
Published in Cell reports (Cambridge) (19-09-2017)“…Tissue-resident memory T cells (TRMs) in mice mediate optimal protective immunity to infection and vaccination, while in humans, the existence and properties…”
Get full text
Journal Article -
2
Dendritic Cells Display Subset and Tissue-Specific Maturation Dynamics over Human Life
Published in Immunity (Cambridge, Mass.) (21-03-2017)“…Maturation and migration to lymph nodes (LNs) constitutes a central paradigm in conventional dendritic cell (cDC) biology but remains poorly defined in humans…”
Get full text
Journal Article -
3
An atlas of B-cell clonal distribution in the human body
Published in Nature biotechnology (01-09-2017)“…B-cell VH region repertoire sequencing of eight anatomical sites in six human donors reveals distinct networks of clone distribution. B-cell responses result…”
Get full text
Journal Article -
4
Lesson From the New York City Out-of-Hospital Uncontrolled Donation After Circulatory Determination of Death Program
Published in Annals of emergency medicine (01-04-2016)“…Study objective In 2006, the Institute of Medicine emphasized substantial potential to expand organ donation opportunities through uncontrolled donation after…”
Get full text
Journal Article -
5
Spatial map of human T cell compartmentalization and maintenance over decades of life
Published in Cell (06-11-2014)“…Mechanisms for human memory T cell differentiation and maintenance have largely been inferred from studies of peripheral blood, though the majority of T cells…”
Get full text
Journal Article -
6
Distribution and Compartmentalization of Human Circulating and Tissue-Resident Memory T Cell Subsets
Published in Immunity (Cambridge, Mass.) (24-01-2013)“…Knowledge of human T cells derives chiefly from studies of peripheral blood, whereas their distribution and function in tissues remains largely unknown. Here,…”
Get full text
Journal Article -
7
Early-life compartmentalization of human T cell differentiation and regulatory function in mucosal and lymphoid tissues
Published in Nature medicine (01-01-2016)“…Early life differentiation and regulatory function of human T cells is confined to particular anatomical sites. It is unclear how the immune response in early…”
Get full text
Journal Article -
8
Tissue reservoirs of antiviral T cell immunity in persistent human CMV infection
Published in The Journal of experimental medicine (06-03-2017)“…T cell responses to viruses are initiated and maintained in tissue sites; however, knowledge of human antiviral T cells is largely derived from blood…”
Get full text
Journal Article -
9
Liver biopsy in assessment of extended criteria donors
Published in Liver transplantation (01-02-2018)“…The safety and liver utilization with prerecovery liver biopsy (PLB) in extended criteria liver donors are unclear. We conducted a retrospective cohort study…”
Get full text
Journal Article -
10
Functional heterogeneity of human tissue-resident memory T cells based on dye efflux capacities
Published in JCI insight (15-11-2018)“…Tissue-resident memory T cells (TRMs) accelerate pathogen clearance through rapid and enhanced functional responses in situ. TRMs are prevalent in diverse…”
Get full text
Journal Article -
11
Mishandling Misconduct: The NSABP Lumpectomy Trial
Published in JAMA : the journal of the American Medical Association (19-10-1994)“…To the Editor.—In his Editorial,1 Dr Rennie apologizes for publishing the study by Dr Lee-Feldstein and colleagues2 and the Editorial by Dr Baue.3 He cites…”
Get full text
Journal Article -
12
Human lymph nodes maintain TCF-1hi memory T cells with high functional potential and clonal diversity throughout life 1
Published in The Journal of immunology (1950) (15-08-2018)“…Translating studies on T cell function and modulation from mouse models to humans requires extrapolating in vivo results on mouse T cell responses in lymphoid…”
Get full text
Journal Article -
13
ED SUMM: B cell VH region repertoire sequencing of 8 anatomical sites in 6 human donors reveals distinct networks of clone distribution: An atlas of B cell clonal distribution in the human body
Published in Nature biotechnology (21-08-2017)“…B cell responses result in clonal expansion, and can occur in a variety of tissues. To define how B cell clones are distributed in the body, we sequenced…”
Get full text
Journal Article -
14
Human Lymph Nodes Maintain TCF-1hi Memory T Cells with High Functional Potential and Clonal Diversity throughout Life
Published in The Journal of immunology (1950) (01-10-2018)“…Translating studies on T cell function and modulation from mouse models to humans requires extrapolating in vivo results on mouse T cell responses in lymphoid…”
Get full text
Journal Article -
15
A Pilot Program to Evaluate Deceased Donor Disease Transmission Risk: The New York Organ Donor Network Infectious Disease Working Group
Published in Transplantation (27-10-2014)“…BACKGROUNDRecent cases of donor-derived infections raise the question of how best to screen donors without excessive restriction of the donor pool. METHODSThe…”
Get full text
Journal Article -
16
Human Lymph Nodes Maintain TCF-1 hi Memory T Cells with High Functional Potential and Clonal Diversity throughout Life
Published in The Journal of immunology (1950) (01-10-2018)“…Translating studies on T cell function and modulation from mouse models to humans requires extrapolating in vivo results on mouse T cell responses in lymphoid…”
Get full text
Journal Article -
17
Hemoglobin A1c testing is associated with improved pancreas utilization for transplant
Published in Progress in transplantation (Aliso Viejo, Calif.) (01-03-2013)“…Aging, higher prevalence of diabetes, worsening obesity, and hyperglycemia among potential donors increase the likelihood that pancreata will be declined by…”
Get full text
Journal Article -
18
Hemoglobin A^sub 1c^ testing is associated with improved pancreas utilization for transplant
Published in Progress in transplantation (Aliso Viejo, Calif.) (01-03-2013)“…Aging, higher prevalence of diabetes, worsening obesity, and hyperglycemia among potential donors increase the likelihood that pancreata will be declined by…”
Get full text
Journal Article -
19
Hemoglobin Alc Testing is Associated with Improved Pancreas Utilization for Transplant
Published in Progress in transplantation (Aliso Viejo, Calif.) (01-03-2013)“…Context Aging, higher prevalence of diabetes, worsening obesity, and hyperglycemia among potential donors increase the likelihood that pancreata will be…”
Get full text
Journal Article -
20
Hemoglobin A lc Testing is Associated with Improved Pancreas Utilization for Transplant
Published in Progress in transplantation (Aliso Viejo, Calif.) (01-03-2013)Get full text
Journal Article