Search Results - "LERNER, HARVEY"

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    Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites by Kumar, Brahma V., Ma, Wenji, Miron, Michelle, Granot, Tomer, Guyer, Rebecca S., Carpenter, Dustin J., Senda, Takashi, Sun, Xiaoyun, Ho, Siu-Hong, Lerner, Harvey, Friedman, Amy L., Shen, Yufeng, Farber, Donna L.

    Published in Cell reports (Cambridge) (19-09-2017)
    “…Tissue-resident memory T cells (TRMs) in mice mediate optimal protective immunity to infection and vaccination, while in humans, the existence and properties…”
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    Dendritic Cells Display Subset and Tissue-Specific Maturation Dynamics over Human Life by Granot, Tomer, Senda, Takashi, Carpenter, Dustin J., Matsuoka, Nobuhide, Weiner, Joshua, Gordon, Claire L., Miron, Michelle, Kumar, Brahma V., Griesemer, Adam, Ho, Siu-Hong, Lerner, Harvey, Thome, Joseph J.C., Connors, Thomas, Reizis, Boris, Farber, Donna L.

    Published in Immunity (Cambridge, Mass.) (21-03-2017)
    “…Maturation and migration to lymph nodes (LNs) constitutes a central paradigm in conventional dendritic cell (cDC) biology but remains poorly defined in humans…”
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    An atlas of B-cell clonal distribution in the human body by Meng, Wenzhao, Zhang, Bochao, Schwartz, Gregory W, Rosenfeld, Aaron M, Ren, Daqiu, Thome, Joseph J C, Carpenter, Dustin J, Matsuoka, Nobuhide, Lerner, Harvey, Friedman, Amy L, Granot, Tomer, Farber, Donna L, Shlomchik, Mark J, Hershberg, Uri, Luning Prak, Eline T

    Published in Nature biotechnology (01-09-2017)
    “…B-cell VH region repertoire sequencing of eight anatomical sites in six human donors reveals distinct networks of clone distribution. B-cell responses result…”
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    Spatial map of human T cell compartmentalization and maintenance over decades of life by Thome, Joseph J C, Yudanin, Naomi, Ohmura, Yoshiaki, Kubota, Masaru, Grinshpun, Boris, Sathaliyawala, Taheri, Kato, Tomoaki, Lerner, Harvey, Shen, Yufeng, Farber, Donna L

    Published in Cell (06-11-2014)
    “…Mechanisms for human memory T cell differentiation and maintenance have largely been inferred from studies of peripheral blood, though the majority of T cells…”
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    Distribution and Compartmentalization of Human Circulating and Tissue-Resident Memory T Cell Subsets by Sathaliyawala, Taheri, Kubota, Masaru, Yudanin, Naomi, Turner, Damian, Camp, Philip, Thome, Joseph J.C., Bickham, Kara L., Lerner, Harvey, Goldstein, Michael, Sykes, Megan, Kato, Tomoaki, Farber, Donna L.

    Published in Immunity (Cambridge, Mass.) (24-01-2013)
    “…Knowledge of human T cells derives chiefly from studies of peripheral blood, whereas their distribution and function in tissues remains largely unknown. Here,…”
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    Early-life compartmentalization of human T cell differentiation and regulatory function in mucosal and lymphoid tissues by Thome, Joseph J C, Bickham, Kara L, Ohmura, Yoshiaki, Kubota, Masaru, Matsuoka, Nobuhide, Gordon, Claire, Granot, Tomer, Griesemer, Adam, Lerner, Harvey, Kato, Tomoaki, Farber, Donna L

    Published in Nature medicine (01-01-2016)
    “…Early life differentiation and regulatory function of human T cells is confined to particular anatomical sites. It is unclear how the immune response in early…”
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    Tissue reservoirs of antiviral T cell immunity in persistent human CMV infection by Gordon, Claire L, Miron, Michelle, Thome, Joseph J C, Matsuoka, Nobuhide, Weiner, Joshua, Rak, Michael A, Igarashi, Suzu, Granot, Tomer, Lerner, Harvey, Goodrum, Felicia, Farber, Donna L

    Published in The Journal of experimental medicine (06-03-2017)
    “…T cell responses to viruses are initiated and maintained in tissue sites; however, knowledge of human antiviral T cells is largely derived from blood…”
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    Liver biopsy in assessment of extended criteria donors by Oliver, Joseph B., Machineni, Praveena, Bongu, Advaith, Patel, Trusha, Nespral, Joseph, Kadric, Carie, Goldstein, Michael J., Lerner, Harvey, Gee, David, Hillbom, Richard, Brown, Lloyd, Washburn, Kenneth, Koneru, Baburao

    Published in Liver transplantation (01-02-2018)
    “…The safety and liver utilization with prerecovery liver biopsy (PLB) in extended criteria liver donors are unclear. We conducted a retrospective cohort study…”
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    Functional heterogeneity of human tissue-resident memory T cells based on dye efflux capacities by Kumar, Brahma V, Kratchmarov, Radomir, Miron, Michelle, Carpenter, Dustin J, Senda, Takashi, Lerner, Harvey, Friedman, Amy, Reiner, Steven L, Farber, Donna L

    Published in JCI insight (15-11-2018)
    “…Tissue-resident memory T cells (TRMs) accelerate pathogen clearance through rapid and enhanced functional responses in situ. TRMs are prevalent in diverse…”
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    Mishandling Misconduct: The NSABP Lumpectomy Trial by Lerner, Harvey J

    “…To the Editor.—In his Editorial,1 Dr Rennie apologizes for publishing the study by Dr Lee-Feldstein and colleagues2 and the Editorial by Dr Baue.3 He cites…”
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    A Pilot Program to Evaluate Deceased Donor Disease Transmission Risk: The New York Organ Donor Network Infectious Disease Working Group by Madan, Rebecca Pellett, Carpini, Kristin Delli, Huprikar, Shirish, Lerner, Harvey, Patel, Gopi, Ratner, Lloyd E, Goldstein, Michael J, Herold, Betsy C

    Published in Transplantation (27-10-2014)
    “…BACKGROUNDRecent cases of donor-derived infections raise the question of how best to screen donors without excessive restriction of the donor pool. METHODSThe…”
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    Hemoglobin A1c testing is associated with improved pancreas utilization for transplant by Torres-Quinones, Maritza, Stern, Jeffrey, Seals, Nicholas, Giglio, Gysel, Meza, Kathryn, Carpini, Kristin Delli, Icitovic, Nikolina, Tajik, Waheed, O'Hara, David, Lerner, Harvey, Goldstein, Michael J

    “…Aging, higher prevalence of diabetes, worsening obesity, and hyperglycemia among potential donors increase the likelihood that pancreata will be declined by…”
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    Hemoglobin A^sub 1c^ testing is associated with improved pancreas utilization for transplant by Torres-Quinones, Maritza, Stern, Jeffrey, Seals, Nicholas, Giglio, Gysel, Meza, Kathryn, Carpini, Kristin Delli, Icitovic, Nikolina, Tajik, Waheed, O'Hara, David, Lerner, Harvey, Goldstein, Michael J

    “…Aging, higher prevalence of diabetes, worsening obesity, and hyperglycemia among potential donors increase the likelihood that pancreata will be declined by…”
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    Hemoglobin Alc Testing is Associated with Improved Pancreas Utilization for Transplant by Torres-Quinones, Maritza, Stern, Jeffrey, Seals, Nicholas, Giglio, Gysel, Meza, Kathryn, Carpini, Kristin Delli, Icitovic, Nikolina, Tajik, Waheed, O'Hara, David, Lerner, Harvey, Goldstein, Michael J.

    “…Context Aging, higher prevalence of diabetes, worsening obesity, and hyperglycemia among potential donors increase the likelihood that pancreata will be…”
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