Search Results - "LEREN, PAUL"

Lamin A/C cardiomyopathy: young onset, high penetrance, and frequent need for heart transplantation by Hasselberg, Nina Eide, Haland, Trine Fink, Saberniak, Jørg, Brekke, Pål Haugar, Berge, Knut Erik, Leren, Trond Paul, Edvardsen, Thor, Haugaa, Kristina Hermann

“…Abstract Aims Lamin A/C (LMNA) mutations cause familial dilated cardiomyopathy (DCM) with frequent conduction blocks and arrhythmias. We explored the…”
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Urban Air Pollution and Mortality in a Cohort of Norwegian Men by Nafstad, Per, Håheim, Lise Lund, Wisløff, Torbjørn, Gram, Frederick, Oftedal, Bente, Holme, Ingar, Hjermann, Ingvar, Leren, Paul

“…We investigated the association between total and cause-specific mortality and individual measures of long-term air pollution exposure in a cohort of Norwegian…”
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Novel mutation in the SLC12A3 gene in a Sri Lankan family with Gitelman syndrome & coexistent diabetes: a case report by Subasinghe, Chandrika Jayakanthi, Sirisena, Nirmala Dushyanthi, Herath, Chula, Berge, Knut Erik, Leren, Trond Paul, Bulugahapitiya, Uditha, Dissanayake, Vajira Harshadeva Weerabaddana

“…Gitelman syndrome (GS) is a rare autosomal recessively inherited salt-wasting tubulopathy associated with mutations in the SLC12A3 gene, which encodes for NaCl…”
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Hypokalaemic Paralysis - A double trouble from concurrent Thyrotoxicosis and Gitelman syndrome: A report of two cases by Subasinghe, Chandrika Jayakanthi, Gunatilake, Sonali Sihindi Chapa, Sirisena, Nirmala Dushyanthi, Berge, Knut Erik, Leren, Trond Paul, Bulugahapitiya, Uditha, Dissanayake, Vajira Harshadeva Weerabaddana

“…Background Hypokalaemic paralysis is a rare group of disorders with concomitant muscle weakness and hypokalaemia. Thyrotoxicosis is a recognized and a common…”
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Mortality in relation to smoking history: 13 years' follow-up of 68,000 Norwegian men and women 35-49 years by Tverdal, A, Thelle, D, Stensvold, I, Leren, P, Bjartveit, K

“…A total of 44,290 men and 24,535 women aged 35-49 have been followed with respect to different causes of death during 13.3 years on average. A detailed history…”
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Pregnancy Outcomes in Familial Hypercholesterolemia: A Registry-Based Study by TOLEIKYTE, Leva, RETTERSTØL, Kjetil, LEREN, Trond Paul, IVERSEN, Per Ole

“…Women with familial hypercholesterolemia (FH) are prone to early cardiovascular disease and death. It is unknown whether FH adversely affects pregnant women…”
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Molecular genetics in 1991 arrhythmia probands and 2782 relatives in Norway: Results from 17 years of genetic testing in a national laboratory by Stava, Tonje Talsnes, Berge, Knut Erik, Haugaa, Kristina Hermann, Smedsrud, Marit Kristine, Leren, Trond P., Bogsrud, Martin Prøven

“…The aim of this study was to explore the prevalence of likely pathogenic or pathogenic variants and assess the diagnostic yield from genetic testing for…”
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Impact of age on excess risk of coronary heart disease in patients with familial hypercholesterolaemia by Mundal, Liv J, Igland, Jannicke, Veierød, Marit B, Holven, Kirsten Bjørklund, Ose, Leiv, Selmer, Randi Marie, Wisloff, Torbjorn, Kristiansen, Ivar S, Tell, Grethe S, Leren, Trond P, Retterstøl, Kjetil

“…The primary objective was to study the risk of acute myocardial infarction (AMI) and coronary heart disease (CHD) in patients with familial…”
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Variants in the CETP gene affect levels of HDL cholesterol by reducing the amount, and not the specific lipid transfer activity, of secreted CETP by Ølnes, Åsa Schawlann, Teigen, Marianne, Laerdahl, Jon K, Leren, Trond P, Strøm, Thea Bismo, Bjune, Katrine

“…Background Cholesteryl ester transfer protein (CETP) transfers cholesteryl esters in plasma from high density lipoprotein (HDL) to very low density lipoprotein…”
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Risk of stroke in genetically verified familial hypercholesterolemia: A prospective matched cohort study by Svendsen, Karianne, Olsen, Thomas, Vinknes, Kathrine J., Mundal, Liv J., Holven, Kirsten B., Bogsrud, Martin P., Leren, Trond P., Igland, Jannicke, Retterstøl, Kjetil

“…Individuals with familial hypercholesterolemia (FH), causing severely elevated LDL-C, are expected to have a higher risk of ischemic stroke. The risk of…”
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Norsk student i tysk fangenskap by Leren, Paul

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Increased risk of peripheral artery disease in persons with familial hypercholesterolaemia: a prospective registry study by Mundal, Liv J, Hovland, Anders, Igland, Jannicke, Vetrhus, Morten, Veierød, Marit Bragelien, Holven, Kirsten Bjørklund, Bogsrud, Martin Prøven, Tell, Grethe Seppola, Leren, Trond Paul, Retterstøl, Kjetil

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Description of a Large Family with Autosomal Dominant Hypercholesterolemia Associated with the APOE p.Leu167del Mutation by Marduel, Marie, Ouguerram, Khadija, Serre, Valérie, Bonnefont-Rousselot, Dominique, Marques-Pinheiro, Alice, Erik Berge, Knut, Devillers, Martine, Luc, Gérald, Lecerf, Jean-Michel, Tosolini, Laurent, Erlich, Danièle, Peloso, Gina M., Stitziel, Nathan, Nitchké, Patrick, Jaïs, Jean-Philippe, Abifadel, Marianne, Kathiresan, Sekar, Leren, Trond Paul, Rabès, Jean-Pierre, Boileau, Catherine, Varret, Mathilde

“…ABSTRACT Apolipoprotein (apo) E mutants are associated with type III hyperlipoproteinemia characterized by high cholesterol and triglycerides levels. Autosomal…”
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Incidence of various types of atherosclerotic disease in patients with genotyped familial hypercholesterolemia by Retterstol, Kjetil, Mundal, Liv, Igland, Jannicke, Seppola Tell, Grethe, Holven, Kirsten, Braglien Veierød, Marit, Leren, Trond Paul

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Lower risk of smoking-related cancer in individuals with familial hypercholesterolemia compared with controls: a prospective matched cohort study by Krogh, Henriette W., Svendsen, Karianne, Igland, Jannicke, Mundal, Liv J., Holven, Kirsten B., Bogsrud, Martin P., Leren, Trond P., Retterstøl, Kjetil

“…According to guidelines, individuals with familial hypercholesterolemia (FH) shall receive lifestyle intervention and intensive lipid-lowering treatment from…”
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Missense mutation Q384K in the APOB gene affecting the large lipid transfer module of apoB reduces the secretion of apoB-100 in the liver without reducing the secretion of apoB-48 in the intestine by Strøm, Thea Bismo, Asprusten, Emil, Laerdahl, Jon K., Øygard, Irene, Hussain, M. Mahmood, Bogsrud, Martin Prøven, Leren, Trond P.

“…•Homozygosity for mutation Q384K in the APOB gene causes hypobetalipoproteinemia.•Mutation Q384K disrupts the structure of the large lipid transfer (LLT)…”
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Risk of Ischemic Stroke and Total Cerebrovascular Disease in Familial Hypercholesterolemia by Hovland, Anders, Mundal, Liv, Igland, Jannicke, Veierød, Marit Bragelien, Holven, Kirsten Bjørklund, Bogsrud, Martin Prøven, Tell, Grethe S, Leren, Trond Paul, Retterstøl, Kjetil

“…Background and Purpose: Familial hypercholesterolemia (FH) is a common autosomal dominant disease leading to increased level of serum LDL (low-density…”
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Risk of Ischemic Stroke and Total Cerebrovascular Disease in Familial Hypercholesterolemia by Hovland, Anders, Mundal, Liv, Igland, Jannicke, Veierød, Marit Bragelien, Holven, Kirsten Bjørklund, Bogsrud, Martin Prøven, Tell, Grethe S, Leren, Trond Paul, Retterstøl, Kjetil

“…Background and Purpose: Familial hypercholesterolemia (FH) is a common autosomal dominant disease leading to increased level of serum LDL (low-density…”
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The Prevalence of Mutations in KCNQ1, KCNH2, and SCN5A in an Unselected National Cohort of Young Sudden Unexplained Death Cases by WINKEL, BO GREGERS, LARSEN, MAIKEN KUDAHL, BERGE, KNUT ERIK, LEREN, TROND PAUL, NISSEN, PETER HENRIK, OLESEN, MORTEN SALLING, HOLLEGAARD, MADS VILHELM, JESPERSEN, THOMAS, YUAN, LEI, NIELSEN, NIKOLAJ, HAUNSØ, STIG, SVENDSEN, JESPER HASTRUP, WANG, YINMAN, KRISTENSEN, INGRID BAYER, JENSEN, HENRIK KJÆRULF, TFELT-HANSEN, JACOB, BANNER, JYTTE

“…Introduction: Sudden unexplained death account for one‐third of all sudden natural deaths in the young (1–35 years). Hitherto, the prevalence of genopositive…”
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The risk of various types of cardiovascular diseases in mutation positive familial hypercholesterolemia; a review by Hovland, Anders, Mundal, Liv J, Veierød, Marit B, Holven, Kirsten B, Bogsrud, Martin Prøven, Tell, Grethe S, Leren, Trond P, Retterstøl, Kjetil

“…Familial hypercholesterolemia (FH) is a common, inherited disease characterized by high levels of low-density lipoprotein Cholesterol (LDL-C) from birth. Any…”
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