Search Results - "LEPAULT, F"

Passive transfer of flt‐3L‐derived dendritic cells delays diabetes development in NOD mice and associates with early production of interleukin (IL)‐4 and IL‐10 in the spleen of recipient mice by MORIN, J., FAIDEAU, B., GAGNERAULT, M.‐C., LEPAULT, F., BOITARD, C., BOUDALY, S.

“…SUMMARY CD11c+/CD11b+dendritic cells (DC) with high levels of major histocompatibility complex (MHC) class II and co‐stimulatory molecules have been derived…”
Get full text

Expression of homing and adhesion molecules in infiltrated islets of Langerhans and salivary glands of nonobese diabetic mice by Faveeuw, C, Gagnerault, MC, Lepault, F

“…The nonobese diabetic mouse is a relevant model for insulin-dependent diabetes mellitus which results from the destruction of pancreatic beta cells by…”
Get full text

The Activity of Immunoregulatory T Cells Mediating Active Tolerance Is Potentiated in Nonobese Diabetic Mice by an IL-4-Based Retroviral Gene Therapy by Yamamoto, Ana Maria, Chernajovsky, Yuti, Lepault, Francoise, Podhajcer, Osvaldo, Feldmann, Marc, Bach, Jean-Francois, Chatenoud, Lucienne

“…Splenocytes from nonobese diabetic mice overexpressing murine IL (mIL)-4 upon recombinant retrovirus infection lose their capacity to transfer diabetes to…”
Get full text

Influence of iron-deficiency anemia on selected thymus functions in mice: thymulin biological activity, T-cell subsets, and thymocyte proliferation by Kuvibidila, S, Dardenne, M, Savino, W, Lepault, F

“…To define the effects of iron deficiency on thymulin biological activity, T-cell subsets, and thymocyte proliferation, C57BL/6 female mice at weaning were fed…”
Get full text

Histamine-producing cell-stimulating activity. Interleukin 3 and granulocyte-macrophage colony-stimulating factor induce de novo synthesis of histidine decarboxylase in hemopoietic progenitor cells by Schneider, E, Pollard, H, Lepault, F, Guy-Grand, D, Minkowski, M, Dy, M

“…Both interleukin 3 (IL-3) and granulocyte-macrophage colony-stimulating factor (GM-CSF) induce increased histamine production by murine hemopoietic cells…”
Get full text

Lymph node T-cells do not optimally transfer diabetes in NOD mice by Lepault, F., Faveeuw, C., Luan, J. J., Gagnerault, M. C.

“…Lymph node T-cells do not optimally transfer diabetes in NOD mice. F Lepault , C Faveeuw , J J Luan and M C Gagnerault Hôpital Necker, CNRS URA 1461, Paris,…”
Get full text

Pancreatic lymph nodes are required for priming of beta cell reactive T cells in NOD mice by Gagnerault, Marie-Claude, Luan, Jian Jian, Lotton, Chantal, Lepault, Françoise

“…Nonobese diabetic (NOD) mice develop spontaneous autoimmune diabetes that results from the destruction of insulin secreting beta cells by diabetogenic T cells…”
Get full text

Synergistic effect of colony-stimulating factors and IL-2 on prothymocyte proliferation linked to the maturation of macrophage/dendritic cells within L3T4-Lyt-2-Ia-Mac- cells by Papiernik, M, Lepault, F, Pontoux, C

“…Bone marrow-derived precursors colonize the thymus, where they constitute the minor L3T4-Lyt2- subset which can give rise to all thymocyte subpopulations. We…”
Get full text

Activation of natural killer T cells by α-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes by Delovitch, Terry L, Bach, Jean-François, Sharif, Shayan, Arreaza, Guillermo A, Zucker, Peter, Mi, Qing-Sheng, Sondhi, Jitin, Naidenko, Olga V, Kronenberg, Mitchell, Koezuka, Yasuhiko, Gombert, Jean-Marc, Leite-de-Moraes, Maria, Gouarin, Christine, Zhu, Ren, Hameg, Agathe, Nakayama, Toshinori, Taniguchi, Masaru, Lepault, Françoise, Lehuen, Agnès, Herbelin, André

“…Type 1 diabetes (T1D) in non-obese diabetic (NOD) mice may be favored by immune dysregulation leading to the hyporesponsiveness of regulatory T cells and…”
Get full text

Characterization of Peripheral Regulatory CD4+ T Cells That Prevent Diabetes Onset in Nonobese Diabetic Mice by Lepault, Francoise, Gagnerault, Marie Claude

“…The period that precedes onset of insulin-dependent diabetes mellitus corresponds to an active dynamic state in which pathogenic autoreactive T cells are kept…”
Get full text

Studies on the thymus in Chagas' disease. II. Thymocyte subset fluctuations in Trypanosoma cruzi-infected mice: relationship to stress by Leite de Moraes, M C, Hontebeyrie-Joskowicz, M, Leboulenger, F, Savino, W, Dardenne, M, Lepault, F

“…Changes in thymic T-cell subsets in mice acutely infected with Trypanosoma cruzi have been studied in both C3H/HeJ and C57BL/6 mice. The significant decrease…”
Get more information

In vitro T cell unresponsiveness following low‐dose injection of anti‐CD3 MoAb by BEN‐AMOR, A., LEITE‐DE‐MORAES, M. C., LEPAULT, F., SCHNEIDER, E., MACHAVOINE, F., ARNOULD, A., CHATENOUD, L., DY, M.

“…SUMMARY Anti‐CD3 MoAb treatment is widely used as an immunosuppressive therapy. In the present study we examined the in vitro T cell response in mice having…”
Get full text

Role of Adhesion Molecules in the Homing and Mobilization of Murine Hematopoietic Stem and Progenitor Cells by Vermeulen, Monica, Le Pesteur, Françoise, Gagnerault, Marie-Claude, Mary, Jean-Yves, Sainteny, Françoise, Lepault, Françoise

“…Bone marrow (BM) transplantation still must overcome multiple difficulties and should benefit from better understanding of stem-cell homing and mobilization…”
Get full text

Modifications of the expression of homing and adhesion molecules in infiltrated islets of Langerhans in NOD mice by Faveeuw, C, Gagnerault, M C, Lepault, F

Get more information

An in vivo assay for thymus-homing bone marrow cells by Lepault, F, Weissman, I. L

Get full text

Role of adhesion molecules in the homing and mobilization of murine hematopoietic stem and progenitor cells by VERMEULEN, M, LE PESTEUR, F, GAGNERAULT, M.-C, MARY, J.-Y, SAINTENY, F, LEPAULT, F

“…Bone marrow (BM) transplantation still must overcome multiple difficulties and should benefit from better understanding of stem-cell homing and mobilization…”
Get full text

Characteristics of thymus-homing bone marrow cells by Lepault, F, Coffman, RL, Weissman, IL

“…Using a short-term in vivo assay, we studied bone marrow cells capable of homing to the thymus of lethally irradiated recipients. In the bone marrow, these…”
Get full text

Role of β-Cells in Type 1 Diabetes Pathogenesis by FAIDEAU, Beatrice, LARGER, Etienne, LEPAULT, Francoise, CAREL, Jean Claude, BOITARD, Christian

“…Role of β-Cells in Type 1 Diabetes Pathogenesis Béatrice Faideau , Etienne Larger , Françoise Lepault , Jean Claude Carel and Christian Boitard From the INSERM…”
Get full text

Role of interleukin-2 receptors in the suppressive effect of spleen cells from anti-CD3-treated mice by Ben-Amor, A, Leite-De-Moraes MdC, Lepault, F, Schneider, E, Machavoine, F, Arnould, A, Chatenoud, L, Dy, M

“…In the present study, we demonstrate that unresponsive spleen T cells from mice injected with a low dose of anti-CD3 mAb (single 10 micrograms i.v. injection)…”
Get more information

Influence of a non-NK complex region of chromosome 6 on CD4+ invariant NKT cell homeostasis by Vallois, D., Gagnerault, M.C., Avner, P., Rogner, U.C., Boitard, C., Benlagha, K., Herbelin, A., Lepault, F.

Get full text