Search Results - "LEO, M. M"

Critical illness-associated diaphragm weakness by Dres, Martin, Goligher, Ewan C., Heunks, Leo M. A., Brochard, Laurent J.

“…Diaphragm weakness is highly prevalent in critically ill patients. It may exist prior to ICU admission and may precipitate the need for mechanical ventilation…”
Get full text

Emergence of a novel human coronavirus threatening human health by Poon, Leo L. M., Peiris, Malik

“…In late December 2019, a cluster of patients with ‘atypical pneumonia’ of unknown etiology was reported in Wuhan, China. A novel human coronavirus, now…”
Get full text

The carbapenem inactivation method (CIM), a simple and low-cost alternative for the Carba NP test to assess phenotypic carbapenemase activity in gram-negative rods by van der Zwaluw, Kim, de Haan, Angela, Pluister, Gerlinde N, Bootsma, Hester J, de Neeling, Albert J, Schouls, Leo M

“…A new phenotypic test, called the Carbapenem Inactivation Method (CIM), was developed to detect carbapenemase activity in Gram-negative rods within eight…”
Get full text

Viral load of SARS-CoV-2 in clinical samples by Pan, Yang, Zhang, Daitao, Yang, Peng, Poon, Leo L M, Wang, Quanyi

Get full text

Physiology of the Respiratory Drive in ICU Patients: Implications for Diagnosis and Treatment by Jonkman, Annemijn H, de Vries, Heder J, Heunks, Leo M A

“…This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2020. Other selected articles can be found online…”
Get full text

Biochar and the Nitrogen Cycle: Introduction by Clough, Tim J, Condron, Leo M

“…Nitrogen (N) is an essential nutrient, and research to date shows that biochar potentially has the ability to manipulate the rates of N cycling in soil systems…”
Get full text

Impact of long-term phosphorus fertilizer inputs on bacterial phoD gene community in a maize field, Northeast China by Chen, Xiaodong, Jiang, Nan, Condron, Leo M., Dunfield, Kari E., Chen, Zhenhua, Wang, Jingkuan, Chen, Lijun

“…The bacterial phoD gene encodes alkaline phosphomonoesterase, an enzyme which plays an important role in the release of plant-available inorganic phosphorus…”
Get full text

CB1 Cannabinoid Receptor Signaling and Biased Signaling by Leo, Luciana M, Abood, Mary E

“…The CB1 cannabinoid receptor is a G-protein coupled receptor highly expressed throughout the central nervous system that is a promising target for the…”
Get full text

Dried Blood Spot Methods in Therapeutic Drug Monitoring: Methods, Assays, and Pitfalls by EDELBROEK, Peter M, VAN DER HEIJDEN, Jacques, STOLK, Leo M. L

“…This article reviews dried blood spot (DBS) sampling in therapeutic drug monitoring. The DBS method involves applying whole blood obtained via a fingerprick to…”
Get full text

Diaphragm Pathology in Critically Ill Patients With COVID-19 and Postmortem Findings From 3 Medical Centers by Shi, Zhonghua, de Vries, Heder J, Vlaar, Alexander P J, van der Hoeven, Johannes, Boon, Reinier A, Heunks, Leo M A, Ottenheijm, Coen A C

Get more information

Revisiting the fundamentals of phosphorus fractionation of sediments and soils by Condron, Leo M., Newman, Susan

“…Introduction Sequential fractionation procedures have been an important tool in the study of phosphorus (P) dynamics in soils and sediments for over 50 years…”
Get full text

Functional Outcomes After Hip Fracture in Independent Community‐Dwelling Patients by Ouellet, Jennifer A., Ouellet, Gregory M., Romegialli, Alison M., Hirsch, Marilyn, Berardi, Lisa, Ramsey, Christine M., Cooney Jr, Leo M., Walke, Lisa M.

“…OBJECTIVES To determine predictors of new activities of daily living (ADLs) disability and worsened mobility disability and secondarily increased daily care…”
Get full text

Official International Association for Therapeutic Drug Monitoring and Clinical Toxicology Guideline: Development and Validation of Dried Blood Spot-Based Methods for Therapeutic Drug Monitoring by Capiau, Sara, Veenhof, Herman, Koster, Remco A, Bergqvist, Yngve, Boettcher, Michael, Halmingh, Otto, Keevil, Brian G, Koch, Birgit C P, Linden, Rafael, Pistos, Constantinos, Stolk, Leo M, Touw, Daan J, Stove, Christophe P, Alffenaar, Jan-Willem C

“…Dried blood spot (DBS) analysis has been introduced more and more into clinical practice to facilitate Therapeutic Drug Monitoring (TDM). To assure the quality…”
Get full text

Synthesis of Metastable Inorganic Solids with Extended Structures by Cordova, Dmitri Leo M., Johnson, David C.

“…The number of known inorganic compounds is dramatically less than predicted due to synthetic challenges, which often constrains products to only the…”
Get full text

Neutralizing antibodies against the SARS-CoV-2 Omicron variant BA.1 following homologous and heterologous CoronaVac or BNT162b2 vaccination by Cheng, Samuel M. S., Mok, Chris Ka Pun, Leung, Yonna W. Y., Ng, Susanna S., Chan, Karl C. K., Ko, Fanny W., Chen, Chunke, Yiu, Karen, Lam, Bosco H. S., Lau, Eric H. Y., Chan, Ken K. P., Luk, Leo L. H., Li, John K. C., Tsang, Leo C. H., Poon, Leo L. M., Hui, David S. C., Peiris, Malik

“…The Omicron variant is rapidly becoming the dominant SARS-CoV-2 virus circulating globally. It is important to define reductions in virus neutralizing activity…”
Get full text

Cost‐Related Medication Nonadherence Among Older Adults: Findings From a Nationally Representative Sample by Chung, Green C., Marottoli, Richard A., Cooney, Leo M., Rhee, Taeho Greg

“…OBJECTIVES To estimate the rate of and risk factors associated with cost‐related medication nonadherence among older adults. DESIGN Cross‐sectional analysis of…”
Get full text

The Collateral Ligament of the Digits of the Hand: Anatomy, Physiology, Biomechanics, Injury, and Treatment by Rozmaryn, Leo M.

“…Ligament injuries are among the most common musculoskeletal injuries seen in clinical practice and ligaments are the most frequently injured structures in a…”
Get full text

The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C − monocytes by Hedrick, Catherine C, Hanna, Richard N, Carlin, Leo M, Hubbeling, Harper G, Nackiewicz, Dominika, Green, Angela M, Punt, Jennifer A, Geissmann, Frederic

“…Ly6C – monocytes patrol blood vessels by crawling along uninflamed vasculature. Hedrick and colleagues show that the transcription factor NR4A1 is required for…”
Get full text

Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis by Riley, Joel S, Quarato, Giovanni, Cloix, Catherine, Lopez, Jonathan, O'Prey, Jim, Pearson, Matthew, Chapman, James, Sesaki, Hiromi, Carlin, Leo M, Passos, João F, Wheeler, Ann P, Oberst, Andrew, Ryan, Kevin M, Tait, Stephen WG

“…During apoptosis, pro‐apoptotic BAX and BAK are activated, causing mitochondrial outer membrane permeabilisation (MOMP), caspase activation and cell death…”
Get full text

TMEM16A channel upregulation in arterial smooth muscle cells produces vasoconstriction during diabetes by Leo, M Dennis, Peixoto-Nieves, Dieniffer, Yin, Wen, Raghavan, Somasundaram, Muralidharan, Padmapriya, Mata-Daboin, Alejandro, Jaggar, Jonathan H

“…The pathological involvement of anion channels in vascular dysfunction that occurs during type 2 diabetes (T2D) is unclear. Here, we tested the hypothesis that…”
Get more information