Search Results - "LEO, C."

High-Accuracy Mass, Spin, and Recoil Predictions of Generic Black-Hole Merger Remnants by Varma, Vijay, Gerosa, Davide, Stein, Leo C, Hébert, François, Zhang, Hao

“…We present accurate fits for the remnant properties of generically precessing binary black holes, trained on large banks of numerical-relativity simulations…”
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Acute and rapid degradation of endogenous proteins by Trim-Away by Clift, Dean, So, Chun, McEwan, William A., James, Leo C., Schuh, Melina

“…Protein depletion is a key approach to understanding the functions of a protein in a biological system. We recently developed the Trim-Away approach in order…”
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SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids by Pellegrini, Laura, Albecka, Anna, Mallery, Donna L., Kellner, Max J., Paul, David, Carter, Andrew P., James, Leo C., Lancaster, Madeline A.

“…Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, leads to respiratory symptoms that can…”
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Neutralizing antibodies against the SARS-CoV-2 Omicron variant BA.1 following homologous and heterologous CoronaVac or BNT162b2 vaccination by Cheng, Samuel M. S., Mok, Chris Ka Pun, Leung, Yonna W. Y., Ng, Susanna S., Chan, Karl C. K., Ko, Fanny W., Chen, Chunke, Yiu, Karen, Lam, Bosco H. S., Lau, Eric H. Y., Chan, Ken K. P., Luk, Leo L. H., Li, John K. C., Tsang, Leo C. H., Poon, Leo L. M., Hui, David S. C., Peiris, Malik

“…The Omicron variant is rapidly becoming the dominant SARS-CoV-2 virus circulating globally. It is important to define reductions in virus neutralizing activity…”
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A Method for the Acute and Rapid Degradation of Endogenous Proteins by Clift, Dean, McEwan, William A., Labzin, Larisa I., Konieczny, Vera, Mogessie, Binyam, James, Leo C., Schuh, Melina

“…Methods for the targeted disruption of protein function have revolutionized science and greatly expedited the systematic characterization of genes. Two main…”
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A review on the emerging applications of cellulose, cellulose derivatives and nanocellulose in carbon capture by Ho, Ngo Anh Dao, Leo, C.P.

“…Carbon capture can be implemented at a large scale only if the CO2 selective materials are abundantly available at low cost. Since the sustainable requirement…”
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Cellular Self-Defense: How Cell-Autonomous Immunity Protects Against Pathogens by Randow, Felix, MacMicking, John D., James, Leo C.

“…Our prevailing view of vertebrate host defense is strongly shaped by the notion of a specialized set of immune cells as sole guardians of antimicrobial…”
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Genetic Code Expansion and Bio-Orthogonal Labeling Reveal Intact HIV-1 Capsids inside the Nucleus by James, Leo C

“…Microscopy is one of the few techniques that can directly observe the HIV-1 capsid as it traverses the cell. However, an extrinsic or intrinsic label is needed…”
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Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion by Papa, Guido, Mallery, Donna L, Albecka, Anna, Welch, Lawrence G, Cattin-Ortolá, Jérôme, Luptak, Jakub, Paul, David, McMahon, Harvey T, Goodfellow, Ian G, Carter, Andrew, Munro, Sean, James, Leo C

“…Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) infects cells by binding to the host cell receptor ACE2 and undergoing virus-host membrane fusion…”
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The molecular mechanisms that drive intracellular neutralization by the antibody-receptor and RING E3 ligase TRIM21 by Kiss, Leo, James, Leo C.

“…The cytosolic antibody receptor and RING E3 ligase TRIM21 targets intracellular, antibody-coated immune complexes for degradation and activates the immune…”
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Bacterial autoaggregation by Trunk, Thomas, Khalil, Hawzeen S, Leo, Jack C

“…Many bacteria, both environmental and pathogenic, exhibit the property of autoaggregation. In autoaggregation (sometimes also called autoagglutination or…”
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RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination by Kiss, Leo, Clift, Dean, Renner, Nadine, Neuhaus, David, James, Leo C.

“…Attachment of ubiquitin (Ub) to proteins is one of the most abundant and versatile of all posttranslational modifications and affects outcomes in essentially…”
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Pregnant giant devil ray (Mobula mobular) bycatch reveals potential Northern Gulf of California pupping ground by Gaskins, Leo C.

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Real-world COVID-19 vaccine effectiveness against the Omicron BA.2 variant in a SARS-CoV-2 infection-naive population by Lau, Jonathan J., Cheng, Samuel M. S., Leung, Kathy, Lee, Cheuk Kwong, Hachim, Asmaa, Tsang, Leo C. H., Yam, Kenny W. H., Chaothai, Sara, Kwan, Kelvin K. H., Chai, Zacary Y. H., Lo, Tiffany H. K., Mori, Masashi, Wu, Chao, Valkenburg, Sophie A., Amarasinghe, Gaya K., Lau, Eric H. Y., Hui, David S. C., Leung, Gabriel M., Peiris, Malik, Wu, Joseph T.

“…The SARS-CoV-2 Omicron variant has demonstrated enhanced transmissibility and escape of vaccine-derived immunity. Although first-generation vaccines remain…”
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Erodibility of Mud–Sand Bed Mixtures by van Rijn, Leo C

“…AbstractThe erodibility of mud–sand bed mixtures has been studied based on experiments in a flume and in a small, vertical tube placed on the bed (Eromes-tube…”
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Sequences in the cytoplasmic tail of SARS-CoV-2 Spike facilitate expression at the cell surface and syncytia formation by Cattin-Ortolá, Jérôme, Welch, Lawrence G., Maslen, Sarah L., Papa, Guido, James, Leo C., Munro, Sean

“…The Spike (S) protein of SARS-CoV-2 binds ACE2 to direct fusion with host cells. S comprises a large external domain, a transmembrane domain, and a short…”
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Unified View of Sediment Transport by Currents and Waves. I: Initiation of Motion, Bed Roughness, and Bed-Load Transport by van Rijn, Leo C

“…Attention is given to the properties of sediment beds over the full range of conditions (silts to gravel), in particular the effect of fine silt on the bed…”
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Type V secretion: mechanism(s) of autotransport through the bacterial outer membrane by Leo, Jack C., Grin, Iwan, Linke, Dirk

“…Autotransport in Gram-negative bacteria denotes the ability of surface-localized proteins to cross the outer membrane (OM) autonomously. Autotransporters…”
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Charcoal, livelihoods, and poverty reduction: Evidence from sub-Saharan Africa by Zulu, Leo C., Richardson, Robert B.

“…More than 80% of urban households in sub-Saharan Africa use charcoal as their main source of cooking energy, and the demand is likely to increase for several…”
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Type V Secretion Systems: An Overview of Passenger Domain Functions by Meuskens, Ina, Saragliadis, Athanasios, Leo, Jack C, Linke, Dirk

“…Bacteria secrete proteins for different purposes such as communication, virulence functions, adhesion to surfaces, nutrient acquisition, or growth inhibition…”
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