Search Results - "LEMKE, J"
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Microstructure and Fracture Behavior of 316L Austenitic Stainless Steel Produced by Selective Laser Melting
Published in Journal of materials science & technology (01-08-2016)“…Selective laser melting is an additive manufacturing method based on local melting of a metal powder bed by a high power laser beam. Fast laser scans are…”
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Getting TRAIL back on track for cancer therapy
Published in Cell death and differentiation (01-09-2014)“…Unlike other members of the TNF superfamily, the TNF-related apoptosis-inducing ligand (TRAIL, also known as Apo2L) possesses the unique capacity to induce…”
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Onto better TRAILs for cancer treatment
Published in Cell death and differentiation (01-05-2016)“…Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand (Apo2L), is a member of the TNF cytokine superfamily. By…”
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An approximate form of Artin’s holomorphy conjecture and non-vanishing of Artin L-functions
Published in Inventiones mathematicae (01-03-2024)“…Let k be a number field and G be a finite group. Let F k G ( Q ) be the family of number fields K with absolute discriminant D K at most Q such that K / k is…”
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Unexpected biases in the distribution of consecutive primes
Published in Proceedings of the National Academy of Sciences - PNAS (02-08-2016)“…Although the sequence of primes is very well distributed in the reduced residue classes (mod q), the distribution of pairs of consecutive primes among the…”
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Articulating communities: Sociocultural perspectives on science education
Published in Journal of research in science teaching (01-03-2001)“…Explains what taking a sociocultural perspective on science education means and discusses classroom interactions, which is also a dominant focus of…”
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Rank Growth of Elliptic Curves in Non-Abelian Extensions
Published in International mathematics research notices (01-12-2021)“…Abstract Given an elliptic curve $E/\mathbb{Q}$, it is a conjecture of Goldfeld that asymptotically half of its quadratic twists will have rank zero and half…”
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Drug and Bile Acid Transporters in Rosuvastatin Hepatic Uptake: Function, Expression, and Pharmacogenetics
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2006)“…Background & Aims The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, or statins, target liver HMG-CoA and are of proven benefit in the…”
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Effective Log-Free Zero Density Estimates for Automorphic L-Functions and the Sato–Tate Conjecture
Published in International mathematics research notices (18-11-2019)“…Abstract Let $K/\mathbb{Q}$ be a number field. Let π and π′ be cuspidal automorphic representations of $\textrm{GL}_{d}(\mathbb{A}_{K})$ and…”
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Selective CDK9 inhibition overcomes TRAIL resistance by concomitant suppression of cFlip and Mcl-1
Published in Cell death and differentiation (01-03-2014)“…Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can induce apoptosis in many cancer cells without causing toxicity in vivo. However, to date,…”
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Transcription of the Escherichia coli Fatty Acid Synthesis Operon fabHDG Is Directly Activated by FadR and Inhibited by ppGpp
Published in Journal of Bacteriology (01-08-2013)“…In Escherichia coli, FadR and FabR are transcriptional regulators that control the expression of fatty acid degradation and unsaturated fatty acid synthesis…”
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Human Skeletal Muscle Drug Transporters Determine Local Exposure and Toxicity of Statins
Published in Circulation research (05-02-2010)“…RATIONALE:The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, or statins, are important drugs used in the treatment and prevention of…”
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DksA and ppGpp directly regulate transcription of the Escherichia coli flagellar cascade
Published in Molecular microbiology (01-12-2009)“…The components of the Escherichia coli flagella apparatus are synthesized in a three-level transcriptional cascade activated by the master regulator FlhDC. The…”
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14
Direct regulation of Escherichia coli ribosomal protein promoters by the transcription factors ppGpp and DksA
Published in Proceedings of the National Academy of Sciences - PNAS (05-04-2011)“…We show here that the promoters for many of the Escherichia coli ribosomal protein operons are regulated directly by two transcription factors, the small RNA…”
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A Novel Approach for Non-Invasive Continuous In-Line Control of Perfusion Cell Cultivations by Raman Spectroscopy
Published in Frontiers in bioengineering and biotechnology (25-04-2022)“…Continuous manufacturing is becoming more important in the biopharmaceutical industry. This processing strategy is favorable, as it is more efficient,…”
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The number of ramified primes in number fields of small degree
Published in Proceedings of the American Mathematical Society (01-08-2017)“…In this paper we investigate the distribution of the number of primes which ramify in number fields of degree d \leq 5. In analogy with the classical Erdős-Kac…”
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An Outbreak of Shiga Toxin—Producing Escherichia coli O104:H4 Hemolytic Uremic Syndrome in Germany: Presentation and Short-term Outcome in Children
Published in Clinical infectious diseases (15-09-2012)“…Background. In May and June 2011 the largest known outbreak of hemolytic uremic syndrome (HUS) occurred in northern Germany. Because, quite unusually, a large…”
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Bounded gaps between primes in number fields and function fields
Published in Proceedings of the American Mathematical Society (01-07-2015)“…The Hardy–Littlewood prime k-tuples conjecture has long been thought to be completely unapproachable with current methods. While this sadly remains true,…”
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Interrelation between macroscopic, microscopic and chemical dilution in hardfacing alloys
Published in Materials & design (05-02-2016)“…A common way to extend service life of steel tools under heavy duty service conditions is the use of hardfacing coatings. Coating an economically feasible base…”
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Upper bounds on number fields of given degree and bounded discriminant
Published in Duke mathematical journal (15-10-2022)Get full text
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