Search Results - "LEMIERE, F"

Quantitative DNA-methylation in Daphnia magna and effects of multigeneration Zn exposure by Vandegehuchte, M.B., Lemière, F., Janssen, C.R.

“…Little research on the epigenetic phenomenon of DNA methylation has been performed with invertebrates. However, a few studies have shown that effects of…”
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Mechanisms of Peptide Oxidation by Hydroxyl Radicals: Insight at the Molecular Scale by Verlackt, C. C. W, Van Boxem, W, Dewaele, D, Lemière, F, Sobott, F, Benedikt, J, Neyts, E. C, Bogaerts, A

“…Molecular dynamics (MD) simulations were performed to provide atomic scale insight in the initial interaction between hydroxyl radicals (OH) and peptide…”
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Stainless steel electrospray probe: A dead end for phosphorylated organic compounds? by Tuytten, R., Lemière, F., Witters, E., Dongen, W. Van, Slegers, H., Newton, R.P., Onckelen, H. Van, Esmans, E.L.

“…A study of the interaction of phosphorylated organic compounds with the stainless components of a liquid chromatography–electrospray ionisation–mass…”
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Synthesis, Cytotoxicity, and Antiplasmodial and Antitrypanosomal Activity of New Neocryptolepine Derivatives by Jonckers, Tim H. M, van Miert, Sabine, Cimanga, Kanyanga, Bailly, Christian, Colson, Pierre, De Pauw-Gillet, Marie-Claire, van den Heuvel, Hilde, Claeys, Magda, Lemière, Filip, Esmans, Eddy L, Rozenski, Jef, Quirijnen, Ludo, Maes, Louis, Dommisse, Roger, Lemière, Guy L. F, Vlietinck, Arnold, Pieters, Luc

“…On the basis of the original lead neocryptolepine or 5-methyl-5H-indolo[2,3-b]quinoline, an alkaloid from Cryptolepis sanguinolenta, derivatives were prepared…”
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Study of a New Rate Increasing “Base Effect” in the Palladium-Catalyzed Amination of Aryl Iodides by Meyers, Caroline, Maes, Bert U. W, Loones, Kristof T. J, Bal, Gunther, Lemière, Guy L. F, Dommisse, Roger A

“…Evidence for an interphase deprotonation of Pd(II)−amine complexes with weak carbonate base has been gained for the first time. When a rate-limiting…”
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Detection of estrogen DNA-adducts in human breast tumor tissue and healthy tissue by combined nano LC-nano ES tandem mass spectrometry by Embrechts, J, Lemière, F, Van Dongen, W, Esmans, E.L, Buytaert, P, Van Marck, E, Kockx, M, Makar, A

“…For the first time estrogen DNA-adducts were identified in DNA human breast tumor tissue using nano-LC coupled to nano-Electrospray Tandem Mass Spectrometry…”
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Online immobilized metal affinity chromatography/mass spectrometric analysis of changes elicited by cCMP in the murine brain phosphoproteome by Ding, S., Bond, A. E., Lemière, F., Tuytten, R., Esmans, E. L., Brenton, A. G., Dudley, E., Newton, R. P.

“…An automated online immobilized metal affinity chromatography/high‐performance liquid chromatography mass spectrometric (IMAC‐HPLC/MS/MS) method was developed…”
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Liquid chromatography–mass spectrometry in nucleoside, nucleotide and modified nucleotide characterization by Esmans, E.L, Broes, D, Hoes, I, Lemière, F, Vanhoutte, K

“…Macromolecules such as deoxyribonucleic acid (DNA) and ribonucleic acid as well as their constituents play an important role in all kinds of biochemical…”
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Synthesis of α‐Carbolines Starting from 2,3‐Dichloropyridines and Substituted Anilines by Hostyn, Steven, Van Baelen, Gitte, Lemière, Guy L. F., Maes, Bert U. W.

“…9H‐α‐Carbolines have been prepared via consecutive intermolecular Buchwald–Hartwig reaction and Pd‐catalyzed intramolecular direct arylation from commercially…”
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Sensitive and specific quantification of the anticancer agent ZD1839 (Gefitinib) in plasma by on-column focusing capillary liquid chromatography–tandem mass spectrometry by Guetens, G., Prenen, H., De Boeck, G., Van Dongen, W., Esmans, E., Lemière, F., van Oosterom, A.T., Schöffski, P., de Bruijn, E.A.

“…The development of an on-column focusing gradient capillary LC method coupled to tandem mass spectrometry (quadrupole-linear ion trap) for the quantitative…”
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Development of a Nanoscale Liquid Chromatography/Electrospray Mass Spectrometry Methodology for the Detection and Identification of DNA Adducts by Vanhoutte, K, Van Dongen, W, Hoes, I, Lemière, F, Esmans, E. L, Van Onckelen, H, Van den Eeckhout, E, van Soest, R. E. J, Hudson, A. J

“…In this work, the coupling of liquid nanochromatography to NanoFlow electrospray mass spectrometry was evaluated for the detection of DNA adducts. The NanoFlow…”
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Analysis of DNA Adducts in DNA Hydrolysates by Capillary Zone Electrophoresis and Capillary Zone Electrophoresis−Electrospray Mass Spectrometry by Deforce, Dieter L. D, Ryniers, Filip P. K, Van den Eeckhout, Elfriede G, Lemière, Filip, Esmans, Eddy L

“…The in vitro adduct formation with phenyl glycidyl ethers (PGEs) was studied on 2‘-deoxynucleotides and DNA. The modified DNA was hydrolyzed enzymatically, and…”
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Equilenin-2′-deoxynucleoside adducts: analysis with nano-liquid chromatography coupled to nano-electrospray tandem mass spectrometry by Embrechts, Jan, Lemière, Filip, Dongen, Walter Van, Esmans, Eddy L.

“…The interaction of 4‐hydroxy metabolites of estrogens with DNA leads to the formation of DNA adducts. These adducts are believed to play an important role in…”
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Urinary Modified Nucleosides as Tumor Markers by Dudley, E., Lemiere, F., Van Dongen, W., Esmans, E., El-Sharkawi, A. M. M., Games, D. E., Newton, R. P., Brenton, A. G.

“…Extracts of urinary nucleosides have been sequentially purified and examined by mass spectrometric analysis. Seventeen modified nucleosides have been…”
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2-Substituted 4-, 5-, and 6-[(1 E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2 H)-ones and 2-substituted 4,5-bis[(1 E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2 H)-ones as potent platelet aggregation inhibitors: Design, synthesis, and SAR studies by Meyers, Caroline, Yáñez, Matilde, Elmaatougi, Abdelaziz, Verhelst, Tom, Coelho, Alberto, Fraiz, Nuria, Lemière, Guy L.F., Garcı´a-Mera, Xerardo, Laguna, Reyes, Cano, Ernesto, Maes, Bert U.W., Sotelo, Eddy

“…A set of regioisomeric 2-substituted pyridazin-3(2 H)-ones containing a 3-oxo-3-phenylprop-1-en-1-yl fragment at either position 4, 5 or 6 and 2-substituted…”
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Narrow-Bore HPLC in Combination with Fluorescence and Electrospray Mass Spectrometric Detection for the Analysis of Cocaine and Metabolites in Human Hair by Clauwaert, Karine M, Van Bocxlaer, Jan F, Lambert, Willy E, Van den Eeckhout, Elfriede G, Lemière, Filip, Esmans, Eddy L, De Leenheer, André P

“…A simple, but sensitive and specific, high-performance liquid chromatographic assay for cocaine, cocaethylene, and benzoylecgonine is described. Using direct…”
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Analysis of the DNA Damage Induced by Phenyl Glycidyl Ether Using Capillary Zone Electrophoresis–Electrospray Mass Spectrometry by Deforce, Dieter L.D., Lemière, Filip, Esmans, Eddy.L., De Leenheer, Andreas, Van den Eeckhout, Elfriede G.

“…Thein vitroadduct formation between phenyl glycidyl ether (PGE) and calf thymus DNA was inves-tigated. Agarose slab gel electrophoresis of DNA incubated with…”
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Analysis of the DNA adducts of phenyl glycidyl ether in a calf thymus DNA hydrolysate by capillary zone electrophoresis-electrospray mass spectrometry : evidence for phosphate alkylation by DEFORCE, D. L. D, LEMIERE, F, HOES, I, MILLECAMPS, R. E. M, ESMANS, E. L, DE LEENHEER, A, VAN DEN EECKHOUT, E. G

“…Calf thymus DNA was reacted in vitro with phenyl glycidyl ether (PGE) and was hydrolysed enzymatically, to the 5'-monophosphate nucleotides using…”
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Short capillary ion-pair high-performance liquid chromatography coupled to electrospray (tandem) mass spectrometry for the simultaneous analysis of nucleoside mono-, di- and triphosphates by Tuytten, R., Lemière, F., Dongen, W. Van, Esmans, E. L., Slegers, H.

“…A liquid chromatography/mass spectrometry (LC/MS) method for the analysis of complex mixtures of nucleoside mono‐, di‐ and triphosphates has been developed. A…”
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Differentiation between isomeric phenylglycidyl ether adducts of 2′-deoxyguanosine and 2′-deoxyguanosine-5′-monophosphate using liquid chromatography/electrospray tandem mass spectrometry by Lemière, Filip, Vanhoutte, Koen, Jonckers, Tim, Marek, Radek, Esmans, Eddy L., Claeys, Magda, Van den Eeckhout, Elfriede, Van Onckelen, Harry

“…The reaction between phenylglycidyl ether and 2′‐deoxyguanosine or 2′‐deoxyguanosine‐5′‐monophosphate yields a variety of different nucleoside and nucleotide…”
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