Search Results - "LEISSNER, Philippe"
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Dynamic single-cell phenotyping of immune cells using the microfluidic platform DropMap
Published in Nature protocols (01-09-2020)“…Characterization of immune responses is currently hampered by the lack of systems enabling quantitative and dynamic phenotypic characterization of individual…”
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A modular transcriptional signature identifies phenotypic heterogeneity of human tuberculosis infection
Published in Nature communications (19-06-2018)“…Whole blood transcriptional signatures distinguishing active tuberculosis patients from asymptomatic latently infected individuals exist. Consensus has not…”
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Diagnostic Performance of Alpha-Fetoprotein, Protein Induced by Vitamin K Absence, Osteopontin, Dickkopf-1 and Its Combinations for Hepatocellular Carcinoma
Published in PloS one (17-03-2016)“…Alpha-fetoprotein (AFP) is the most widely used serum biomarker for hepatocellular carcinoma (HCC), despite its limitations. As complementary biomarkers,…”
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Comparison of DNA extraction methods for 16S rRNA gene sequencing in the analysis of the human gut microbiome
Published in Scientific reports (24-06-2023)“…The gut microbiome is widely analyzed using high-throughput sequencing, such as 16S rRNA gene amplicon sequencing and shotgun metagenomic sequencing (SMS). DNA…”
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Exploring the gut microbiota in patients with pre-diabetes and treatment naïve diabetes type 2 - a pilot study
Published in BMC endocrine disorders (21-08-2023)“…Abstract Background Compared to their healthy counterparts, patients with type 2 diabetes (T2D) can exhibit an altered gut microbiota composition, correlated…”
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Herpes DNAemia and TTV Viraemia in Intensive Care Unit Critically Ill Patients: A Single-Centre Prospective Longitudinal Study
Published in Frontiers in immunology (02-11-2021)“…We analysed blood DNAemia of TTV and four herpesviruses (CMV, EBV, HHV6, and HSV-1) in the REAnimation Low Immune Status Marker (REALISM) cohort of critically…”
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Human Endogenous Retrovirus K (HML-2) Elements in the Plasma of People with Lymphoma and Breast Cancer
Published in Journal of Virology (01-10-2008)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Author Correction: Dynamic single-cell phenotyping of immune cells using the microfluidic platform DropMap
Published in Nature protocols (01-08-2021)“…A Correction to this paper has been published: https://doi.org/10.1038/s41596-021-00492-7…”
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Characterization and analytical validation of a new antigenic rapid diagnostic test for Ebola virus disease detection
Published in PLoS neglected tropical diseases (01-01-2020)“…Hemorrhagic fever outbreaks are difficult to diagnose and control in part because of a lack of low-cost and easily accessible diagnostic structures in…”
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Oncogenic cooperation between H-Twist and N-Myc overrides failsafe programs in cancer cells
Published in Cancer cell (01-12-2004)“…N-Myc oncogene amplification is a frequent event in neuroblastoma and is strongly correlated with advanced disease stage and treatment failure. Similarly to…”
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Longitudinal study of cytokine and immune transcription factor mRNA expression in septic shock
Published in Clinical immunology (Orlando, Fla.) (2005)“…Success in treating severe sepsis will require relevant tools to monitor the patient immunoinflammatory status. This study aimed to investigate the feasibility…”
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Prognostic significance of urokinase plasminogen activator and plasminogen activator inhibitor-1 mRNA expression in lymph node- and hormone receptor-positive breast cancer
Published in BMC cancer (31-08-2006)“…One of the most thoroughly studied systems in relation to its prognostic relevance in patients with breast cancer, is the plasminogen activation system that…”
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Genome-wide analysis of gene expression in neuroblastomas detected by mass screening
Published in Cancer letters (08-07-2005)“…Neuroblastoma (NB) is the most common extracranial solid tumor of childhood and the third most common pediatric cancer. Although numerous factors including…”
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Development of Minimal Lentivirus Vectors Derived from Simian Immunodeficiency Virus (SIVmac251) and Their Use for Gene Transfer into Human Dendritic Cells
Published in Journal of Virology (01-09-2000)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Multiparametric duplex real-time nucleic acid sequence-based amplification assay for mRNA profiling
Published in BioTechniques (01-09-2004)“…Nucleic acid sequence-based amplification (NASBA) is a sensitive isothermal transcription-based amplification method. We have developed real-time NASBA assays…”
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DNA nucleic acid sequence-based amplification-based genotyping for polymorphism analysis
Published in BioTechniques (01-10-2004)“…Nucleic acid sequence-based amplification (NASBA) is a sensitive isothermal transcription-based amplification method known to be a suitable tool for RNA…”
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Blood transcriptomics reveal the evolution and resolution of the immune response in tuberculosis
Published in The Journal of experimental medicine (04-10-2021)“…Blood transcriptomics have revealed major characteristics of the immune response in active TB, but the signature early after infection is unknown. In a unique…”
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ProNGF is a potential diagnostic biomarker for thyroid cancer
Published in Oncotarget (10-05-2016)“…The precursor for nerve growth factor (proNGF) is expressed in some cancers but its clinicopathological significance is unclear. The present study aimed to…”
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Concomitant Assessment of Monocyte HLA-DR Expression and Ex Vivo TNF-α Release as Markers of Adverse Outcome after Various Injuries-Insights from the REALISM Study
Published in Journal of clinical medicine (01-01-2022)“…Intensive care unit (ICU) patients develop an altered host immune response after severe injuries. This response may evolve towards a state of persistent…”
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