Search Results - "LEISSINGER, C"
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Desmopressin (DDAVP) in the management of patients with congenital bleeding disorders
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-03-2014)“…Summary Bleeding disorders, including haemophilia, von Willebrand disease, and platelet function abnormalities pose a substantial, ongoing management…”
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Molecular pathogenesis and heterogeneity in type 3 VWD families in U.S. Zimmerman program
Published in Journal of thrombosis and haemostasis (01-07-2022)“…Background Type 3 von Willebrand Disease (VWD) is a rare and severe form of VWD characterized by the absence of von Willebrand factor (VWF). Objectives As part…”
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Laboratory variability in the diagnosis of type 2 VWD variants
Published in Journal of thrombosis and haemostasis (01-01-2021)“…Essentials Patients with von Willebrand disease were enrolled in our study. Type 2 VWD diagnoses were based on original test results. Repeat evaluation…”
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Comparative pharmacokinetics of rVIII-SingleChain and octocog alfa (Advate®) in patients with severe haemophilia A
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-09-2016)“…Background rVIII‐SingleChain, a novel recombinant factor VIII (rFVIII), has been designed as a B‐domain truncated construct with covalently bonded heavy and…”
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Health-related quality of life in patients with haemophilia and inhibitors on prophylaxis with anti-inhibitor complex concentrate: results from the Pro-FEIBA study
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-09-2013)“…Summary Patients with haemophilia A and inhibitors are at high risk for severe bleeding, progression of joint disease and deterioration of health‐related…”
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Assessing the impact of age, race, ethnicity and inhibitor status on functional limitations of patients with severe and moderately severe haemophilia A
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-11-2011)“…Few data exist on the impact of age and inhibitor status on activity levels among patients with severe and moderately severe haemophilia A. The aim of this…”
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Quantifying adherence to treatment and its relationship to quality of life in a well-characterized haemophilia population
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-09-2007)“…It is known that chronically ill patients adhere to medical treatment plans only 50% of the time [1]. Adherence to treatment with factor infusion therapy in…”
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Current prescription of prophylactic factor infusions and perceived adherence for children and adolescents with haemophilia: a survey of haemophilia healthcare professionals in the United States
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-07-2012)“…The primary goal of prophylaxis in patients with severe haemophilia is to convert the phenotype from severe to moderate and to prevent the development of…”
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Opinions on radiosynovectomy for chronic haemophilic synovitis: point/counterpoint
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-11-2012)“…Summary Joint bleeding is the hallmark of severe haemophilia and the major cause of disability in patients with this coagulopathy. Repeated bleeding into the…”
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Prophylactic treatment with activated prothrombin complex concentrate (FEIBA®) reduces the frequency of bleeding episodes in paediatric patients with haemophilia A and inhibitors
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-05-2007)“…Orthopaedic complications are among the most disabling sequelae occurring in patients with haemophilia and inhibitors. Recurrent or refractory joint bleeds can…”
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Physician preferences for medication attributes for the prophylactic treatment of patients with severe haemophilia A with inhibitors to factor VIII
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-01-2013)“…Summary Prophylaxis may be beneficial for patients with severe haemophilia A who have developed inhibitors to factor VIII. The aim of this study was to…”
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Inhibitor treatment in haemophilias A and B: summary statement for the 2006 international consensus conference
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-12-2006)“…Participants in an international conference on the management of haemophilia patients with inhibitors developed a jointly authored summary of the findings and…”
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Prophylaxis in haemophilia patients with inhibitors
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-12-2006)“…The presence of high titre inhibitors makes the treatment of bleeding episodes in haemophilia patients difficult and increases the risk of uncontrollable…”
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A systematic approach to controlling problem bleeds in patients with severe congenital haemophilia A and high-titre inhibitors
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-05-2007)“…The presence of inhibitory antibodies to clotting factors complicates the treatment of bleeding in haemophilia patients. For patients with high‐titre…”
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Case studies in the management of refractory bleeding in patients with haemophilia A and inhibitors
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-05-2013)“…Summary In haemophilia patients with well‐established high‐titer inhibitors, even seemingly minor acute bleeding episodes or surgical procedures may become…”
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