Search Results - "LEHNER, Małgorzata"

Sex-Related Predisposition to Post-Traumatic Stress Disorder Development-The Role of Neuropeptides by Lehner, Małgorzata, Skórzewska, Anna, Wisłowska-Stanek, Aleksandra

“…Post-traumatic stress disorder (PTSD) is characterized by re-experiencing a traumatic event, avoidance, negative alterations in cognitions and mood,…”
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The effect of chronic administration of corticosterone on anxiety- and depression-like behavior and the expression of GABA-A receptor alpha-2 subunits in brain structures of low- and high-anxiety rats by Skórzewska, Anna, Lehner, Małgorzata, Wisłowska-Stanek, Aleksandra, Krząścik, Paweł, Ziemba, Andrzej, Płaźnik, Adam

“…The aim of this study was to examine changes in rat emotional behavior and determine differences in the expression of GABA-A receptor alpha-2 subunits in brain…”
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Non-parametric analysis of neurochemical effects and Arc expression in amphetamine-induced 50-kHz ultrasonic vocalization by Hamed, Adam, Daszczuk, Patrycja, Kursa, Miron Bartosz, Turzyńska, Danuta, Sobolewska, Alicja, Lehner, Małgorzata, Boguszewski, Paweł M., Szyndler, Janusz

“…•Re-exposure to amphetamine increased 50-kHz USVs comparing to control.•50-kHz USVs do not correlate with distance covered by the investigated…”
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Changes in the brain expression of alpha-2 subunits of the GABA-A receptor after chronic restraint stress in low- and high-anxiety rats by Wisłowska-Stanek, Aleksandra, Lehner, Małgorzata, Skórzewska, Anna, Krząścik, Paweł, Maciejak, Piotr, Szyndler, Janusz, Ziemba, Andrzej, Płaźnik, Adam

“…•Chronic restraint stress decreased high anxiety rats (HR) activity in Porsolt test.•HR restraint rats had decreased alpha-2 GABA-A receptors density in…”
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κ-opioid receptor as a key mediator in the regulation of appetitive 50-kHz ultrasonic vocalizations by Hamed, Adam, Szyndler, Janusz, Taracha, Ewa, Turzyńska, Danuta, Sobolewska, Alicja, Lehner, Małgorzata, Krząścik, Paweł, Daszczuk, Patrycja

“…Rationale Acute administration of high doses of morphine reduced 50-kHz ultrasonic vocalizations (USVs). Although morphine meets the classical criteria for…”
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Dopaminergic system activity under stress condition - seeking individual differences, preclinical studies by Gryz, Marek, Lehner, Małgorzata, Wisłowska-Stanek, Aleksandra, Płaźnik, Adam

“…Dopaminergic system activity in limbic structures (reward system) is related to motivational processes and adaptation to changing environmental conditions…”
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The amphetamine-associated context exerts a stronger motivational effect in low-anxiety rats than in high-anxiety rats by Lehner, Małgorzata, Gryz, Marek, Wisłowska-Stanek, Aleksandra, Turzyńska, Danuta, Sobolewska, Alicja, Skórzewska, Anna, Płaźnik, Adam

“…This study used the conditioned place preference test to explore the effects of subchronic amphetamine administration on drug-associated cues in rats with…”
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Chronic restraint increases apoptosis in the hippocampus of rats with high responsiveness to fear stimuli by Lehner, Małgorzata, Wisłowska-Stanek, Aleksandra, Skórzewska, Anna, Płaźnik, Adam

“…•High anxiety rats (HR) have increased stress-induced apoptosis in the rat hippocampus.•Chronic corticosterone increases apoptosis of HR and low anxiety…”
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Midazolam treatment before re-exposure to contextual fear reduces freezing behavior and amygdala activity differentially in high- and low-anxiety rats by Skórzewska, Anna, Lehner, Małgorzata, Wisłowska-Stanek, Aleksandra, Turzyńska, Danuta, Sobolewska, Alicja, Krząścik, Paweł, Płaźnik, Adam

“…The aim of this study was to examine the effects of benzodiazepine (midazolam) administration on rat conditioned fear responses and on local brain activity…”
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The effects of morphine and morphine conditioned context on 50 kHz ultrasonic vocalisation in rats by Hamed, Adam, Taracha, Ewa, Szyndler, Janusz, Krząścik, Paweł, Lehner, Małgorzata, Maciejak, Piotr, Skórzewska, Anna, Płaźnik, Adam

“…The 50 kHz ultrasonic vocalisations (USVs) that are emitted by rats are dependent on activity of dopaminergic neurons projecting from the ventral tegmental…”
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High-anxiety rats are less sensitive to the rewarding affects of amphetamine on 50kHz USV by Lehner, Małgorzata H., Taracha, Ewa, Kaniuga, Ewelina, Wisłowska-Stanek, Aleksandra, Wróbel, Jacek, Sobolewska, Alicja, Turzyńska, Danuta, Skórzewska, Anna, Płaźnik, Adam

“…•Amphetamine enhances appetitive 50kHz vocalisation in rats.•Amphetamine's effect is stronger in low anxiety (LR) than in high anxiety rats (HR).•LR had…”
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Mapping of c-Fos expression in the rat brain during the evolution of pentylenetetrazol-kindled seizures by Szyndler, Janusz, Maciejak, Piotr, Turzyńska, Danuta, Sobolewska, Alicja, Taracha, Ewa, Skórzewska, Anna, Lehner, Małgorzata, Bidziński, Andrzej, Hamed, Adam, Wisłowska-Stanek, Aleksandra, Krząścik, Paweł, Płaźnik, Adam

“…Abstract c-Fos protein immunocytochemistry was used to map the brain structures recruited during the evolution of seizures that follows repeated administration…”
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Changes in the concentration of amino acids in the hippocampus of pentylenetetrazole-kindled rats by Szyndler, Janusz, Maciejak, Piotr, Turzyńska, Danuta, Sobolewska, Alicja, Lehner, Małgorzata, Taracha, Ewa, Walkowiak, Jerzy, Skórzewska, Anna, Wisłowska-Stanek, Aleksandra, Hamed, Adam, Bidziński, Andrzej, Płaźnik, Adam

“…It is not well recognized how disturbances in the local metabolism of some amino acids, especially glutamate and GABA, may lead to seizures. In the presented…”
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Changes in the Egr1 and Arc expression in brain structures of pentylenetetrazole-kindled rats by Szyndler, Janusz, Maciejak, Piotr, Wisłowska-Stanek, Aleksandra, Lehner, Małgorzata, Płaźnik, Adam

“…Epileptogenesis is regarded as a complicated and relatively poorly understood phenomenon. Some of immediate early genes (IEGs) as egr1 (zif268) or arc (arg3.1)…”
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The influence of the long-term administration of Curcuma longa extract on learning and spatial memory as well as the concentration of brain neurotransmitters and level of plasma corticosterone in aged rats by Pyrzanowska, Justyna, Piechal, Agnieszka, Blecharz-Klin, Kamilla, Lehner, Małgorzata, Skórzewska, Anna, Turzyńska, Danuta, Sobolewska, Alicja, Plaznik, Adam, Widy-Tyszkiewicz, Ewa

“…The effects of chronic pre-treatment with a standardised extract of Curcuma longa on learning and spatial memory in aged 24-month old male Wistar rats were…”
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The effects of buspirone and diazepam on aversive context- and social isolation-induced ultrasonic vocalisation by Hamed, Adam, Jaroszewski, Tomasz, Maciejak, Piotr, Szyndler, Janusz, Lehner, Małgorzata, Kamecka, Ita, Olczak, Mieszko, Kuzinska, Urszula, Taracha, Ewa, Płaźnik, Adam

“…Abstract Rats emit two types of high-frequency vocalisations (aversive and appetitive calls) in different behavioural situations. The aims of this paper were…”
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The effects of group III mGluR ligands on pentylenetetrazol-induced kindling of seizures and hippocampal amino acids concentration by Maciejak, Piotr, Szyndler, Janusz, Turzyńska, Danuta, Sobolewska, Alicja, Taracha, Ewa, Skórzewska, Anna, Lehner, Małgorzata, Bidziński, Andrzej, Hamed, Adam, Wisłowska-Stanek, Aleksandra, Płaźnik, Adam

“…Abstract Considering the contribution of hippocampal formation and glutamate-mediated signalling to epileptogenesis, we investigated the effects of group III…”
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The expression of c-Fos and colocalisation of c-Fos and glucocorticoid receptors in brain structures of low and high anxiety rats subjected to extinction trials and re-learning of a conditioned fear response by Lehner, Małgorzata, Wisłowska-Stanek, Aleksandra, Taracha, Ewa, Maciejak, Piotr, Szyndler, Janusz, Skórzewska, Anna, Turzyńska, Danuta, Sobolewska, Alicja, Hamed, Adam, Bidziński, Andrzej, Płaźnik, Adam

“…We designed an animal model to examine the mechanisms of differences in individual responses to aversive stimuli. We used the rat freezing response in the…”
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Effects of morphine and methadone treatment on mRNA expression of Gα(i) subunits in rat brains by Zelek-Molik, Agnieszka, Taracha, Ewa, Nawrat, Dominika, Bielawski, Adam, Lehner, Małgorzata, Płaźnik, Adam, Nalepa, Irena

“…Methadone is clinically effective as substitution therapy in patients with opioid dependence. The diversity of methadone and morphine in their intracellular…”
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Methadone is substantially less effective than morphine in modifying locomotor and brain Fos responses to subsequent methadone challenge in rats by Taracha, Ewa, Chrapusta, Stanisław J., Lehner, Małgorzata, Skórzewska, Anna, Płaźnik, Adam

“…Heroin addicts can benefit from methadone substitution therapy. However, little is known about the significance of pre-exposure to opioids for psychoactive…”
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