Search Results - "LEHMANN, T. E"

Design and Optimization of 20-O-Linked Camptothecin Glycoconjugates as Anticancer Agents by Lerchen, Hans-Georg, Baumgarten, Joerg, von dem Bruch, Karsten, Lehmann, Thomas E, Sperzel, Michael, Kempka, Grazyna, Fiebig, Heinz-Herbert

“…To improve the biological profile of 20(S)-camptothecin, a novel class of 20-O-linked camptothecin glycoconjugates has been designed for preferential cellular…”
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Plasmodium vivax CS peptides display conformational preferences for folded forms in solution by Lehmann, T.E., Kroon, G., Dyson, H.J., Lorenzo, M.A., Bermúdez, H., Perez, H.

“…: Spectroscopic techniques have been used to study the conformations of several synthetic peptides with sequences corresponding to the repeat regions of the…”
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Discovery and evaluation of piperidinyl carboxylic acid derivatives as potent α4β1 integrin antagonists by MÜLLER, G, ALBERS, M, FISCHER, R, HESSLER, G, LEHMANN, T. E, OKIGAMI, H, TAJIMI, M, BACON, K, RÖLLE, T

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Coordination Chemistry of Co(II)-Bleomycin:  Its Investigation through NMR and Molecular Dynamics by Lehmann, Teresa E, Serrano, Maria Luisa, Que, Lawrence

“…Previous studies on the coordination chemistry of Co−bleomycin have suggested the secondary amine in β-aminoalanine, the N5 and N1 nitrogens in the pyrimidine…”
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Discovery and evaluation of piperidinyl carboxylic acid derivatives as potent alpha(4)beta(1) integrin antagonists by Müller, G, Albers, M, Fischer, R, Hessler, G, Lehmann, T E, Okigami, H, Tajimi, M, Bacon, K, Rölle, T

“…Piperidinyl carboxylic acid-based derivatives were prepared as antagonists of the leukocyte cell adhesion process that is mediated through the interaction of…”
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NMR Studies of the Paramagnetic Complex Fe(II)−Bleomycin by Lehmann, Teresa E, Ming, Li-June, Rosen, Mark E, Que, Lawrence

“…The coordination chemistry of the iron(II) complex of the antitumor drug bleomycin has been extensively investigated with a number of spectroscopic and…”
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Photochemistry of 4‘-Benzophenone-Substituted Nucleoside Derivatives as Models for Ribonucleotide Reductases:  Competing Generation of 3‘-Radicals and Photoenols by Lehmann, Thomas E, Müller, Gerhard, Berkessel, Albrecht

“…Ribonucleotide reductases (RNRs) catalyze the 2‘-reduction of ribonucleotides, thus providing 2‘-deoxyribonucleotides, the monomers for DNA-biosynthesis. The…”
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Synthesis, characterization and olefin polymerization studies of iron(II) and cobalt(II) catalysts bearing 2,6-bis(pyrazol-1-yl)pyridines and 2,6-bis(pyrazol-1-ylmethyl)pyridines ligands by Karam, Arquímedes R., Catarí, Edgar L., López-Linares, Francisco, Agrifoglio, Giuseppe, Albano, Carmen L., Díaz-Barrios, Antonio, Lehmann, Teresa E., Pekerar, Sara V., Albornoz, Luis A., Atencio, Reinaldo, González, Teresa, Ortega, Heriberto B., Joskowics, Pablo

“…The complexes Py(PzR 3) 2MCl 2 (R = H, Me; M = Fe, Co) and Py(CH 2 PzR 3) 2MCl 2 (R = H, Me; M = Fe, Co) have been synthesized, characterized and used in the…”
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Molecular modeling of the three-dimensional structure of Fe(II)-bleomycin: are the Co(II) and Fe(II) adducts isostructural? by Lehmann, Teresa E

“…The molecular modeling of Co(II)-bleomycin previously performed by us through NMR and molecular dynamics indicates that the most favorable structure for this…”
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Structural study of copper(I)-bleomycin by Lehmann, Teresa E

“…Previous NMR studies on Cu(I)-bleomycin have suggested that this adduct has a geometry distinct from Fe(II)BLM. The coordination chemistry of this bleomycin…”
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Process Development and Pilot Plant Scale Synthesis of Spiro[3.5]nonane-6,8-dione by Lehmann, Thomas E, Kuhn, Oliver, Krüger, Jochen

“…A two step synthesis of spiro[3.5]nonane-6,8-dione is reported which allows the production of the target molecule on a pilot plant scale. The first step of the…”
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Stereoselective Synthesis of 4‘-Benzophenone-Substituted Nucleoside Analogs:  Photoactive Models for Ribonucleotide Reductases by Lehmann, Thomas E, Berkessel, Albrecht

“…Ribonucleotide reductases (RNRs) catalyze the 2‘-reduction of ribonucleotides, thus providing 2‘-deoxyribonucleotides, the monomers for DNA biosynthesis. The…”
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