Search Results - "LEGRO, R. S"

Bidirectional Mendelian randomization to explore the causal relationships between body mass index and polycystic ovary syndrome by Brower, M A, Hai, Y, Jones, M R, Guo, X, Chen, Y -D I, Rotter, J I, Krauss, R M, Legro, R S, Azziz, R, Goodarzi, M O

“…Abstract STUDY QUESTION What are the causal relationships between polycystic ovary syndrome (PCOS) and body mass index (BMI)? SUMMARY ANSWER Bidirectional…”
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A fasting glucose to insulin ratio is a useful measure of insulin sensitivity in women with polycystic ovary syndrome by LEGRO, R. S, FINEGOOD, D, DUNAIF, A

“…Women with polycystic ovary syndrome (PCOS) are profoundly insulin resistant, and the resultant hyperinsulinemia exacerbates the reproductive abnormalities of…”
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Prevalence and predictors of risk for type 2 Diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome : A prospective, controlled study in 254 affected women by LEGRO, R. S, KUNSELMAN, A. R, DODSON, W. C, DUNAIF, A

“…Women with polycystic ovary syndrome (PCOS) are insulin resistant, have insulin secretory defects, and are at high risk for glucose intolerance. We performed…”
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Candidate Gene Region for Polycystic Ovary Syndrome on Chromosome 19p13.2 by Urbanek, M., Woodroffe, A., Ewens, K. G., Diamanti-Kandarakis, E., Legro, R. S., Strauss, J. F., Dunaif, A., Spielman, R. S.

“…Context: Polycystic ovary syndrome (PCOS) is a common endocrine disorder that is believed to have a genetic basis. However, no specific susceptibility gene or…”
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Current perspectives of insulin resistance and polycystic ovary syndrome by Pauli, J. M., Raja-Khan, N., Wu, X., Legro, R. S.

“…Diabet. Med. 28, 1445–1454 (2011) Aims  To review the relationship between insulin resistance and polycystic ovary syndrome. Methods  A literature review…”
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Estrogen and progesterone exposure is reduced in response to energy deficiency in women aged 25–40 years by Williams, N.I., Reed, J.L., Leidy, H.J., Legro, R.S., De Souza, M.J.

“…BACKGROUND Alterations in circulating steroids are believed to be important mediators of the impact that diet and exercise have on breast cancer risk and…”
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Epigenetic Modification of the X Chromosome Influences Susceptibility to Polycystic Ovary Syndrome by Hickey, T. E., Legro, R. S., Norman, R. J.

“…Context: The cause of polycystic ovary syndrome (PCOS) is unknown, although genetic and environmental influences are clearly implicated. Some genetic studies…”
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Rapid maturation of the reproductive axis during perimenarche independent of body composition by LEGRO, R. S, HUNG MO LIN, DEMERS, L. M, LLOYD, T

“…The development of the reproductive axis is thought to be a gradual process, but our understanding of the complex endocrine changes that accompany the…”
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Peripubertal estrogen levels and physical activity affect femur geometry in young adult women by Devlin, M. J, Stetter, C. M, Lin, H.-M, Beck, T. J, Legro, R. S, Petit, M. A, Lieberman, D. E, Lloyd, T

“…Summary The growing skeleton is particularly responsive to exercise around the time of puberty, suggesting a possible role for estrogen in mechanical…”
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Top 10 priorities for future infertility research: an international consensus development study by Duffy, J M N, Adamson, G D, Benson, E, Bhattacharya, S, Bofill, M, Brian, K, Collura, B, Curtis, C, Evers, J L H, Farquharson, R G, Fincham, A, Franik, S, Giudice, L C, Glanville, E, Hickey, M, Horne, A W, Hull, M L, Johnson, N P, Jordan, V, Khalaf, Y, Knijnenburg, J M L, Legro, R S, Lensen, S, MacKenzie, J, Mavrelos, D, Mol, B W, Morbeck, D E, Nagels, H, Ng, E H Y, Niederberger, C, Otter, A S, Puscasiu, L, Rautakallio-Hokkanen, S, Sadler, L, Sarris, I, Showell, M, Stewart, J, Strandell, A, Strawbridge, C, Vail, A, van Wely, M, Vercoe, M, Vuong, N L, Wang, A Y, Wang, R, Wilkinson, J, Wong, K, Wong, T Y, Farquhar, C M

“…Abstract STUDY QUESTION Can the priorities for future research in infertility be identified? SUMMARY ANSWER The top 10 research priorities for the four areas…”
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Sildenafil citrate in the treatment of pain in primary dysmenorrhea: a randomized controlled trial by Dmitrovic, R., Kunselman, A.R., Legro, R. S.

“…STUDY QUESTION Is a vaginal preparation of sildenafil citrate capable of alleviating acute menstrual pain in patients with primary dysmenorrhea (PD)? SUMMARY…”
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Ovarian stimulation strategies for intrauterine insemination in couples with unexplained infertility: a systematic review and individual participant data meta-analysis by Wessel, J A, Danhof, N A, van Eekelen, R, Diamond, M P, Legro, R S, Peeraer, K, D’Hooghe, T M, Erdem, M, Dankert, T, Cohlen, B J, Thyagaraju, C, Mol, B W J, Showell, M, van Wely, M, Mochtar, M H, Wang, R

“…Abstract BACKGROUND Intrauterine insemination with ovarian stimulation (IUI-OS) is a first-line treatment for unexplained infertility. Gonadotrophins,…”
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Polycystic ovary syndrome: Current and future treatment paradigms by Legro, Richard S.

“…Polycystic ovary syndrome is characterized by excess levels of circulating androgens and by chronic anovulation. Although the fundamental pathophysiologic…”
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Evidence summaries and recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome: assessment and treatment of infertility by Costello, M F, Misso, M L, Balen, A, Boyle, J, Devoto, L, Garad, R M, Hart, R, Johnson, L, Jordan, C, Legro, R S, Norman, R J, Mocanu, E, Qiao, J, Rodgers, R J, Rombauts, L, Tassone, E C, Thangaratinam, S, Vanky, E, Teede, H J

“…Abstract STUDY QUESTION What is the recommended assessment and management of infertile women with polycystic ovary syndrome (PCOS), based on the best available…”
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Evidence for gonadotrophin secretory and steroidogenic abnormalities in brothers of women with polycystic ovary syndrome by Liu, D.M., Torchen, L.C., Sung, Y., Paparodis, R., Legro, R.S., Grebe, S.K., Singh, R.J., Taylor, R.L., Dunaif, A.

“…STUDY QUESTION Are there abnormalities in gonadotrophin secretion, adrenal steroidogenesis and/or testicular steroidogenesis in brothers of women with…”
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Polycystic ovary syndrome. Phenotype to genotype by Legro, R S

“…Available studies suggest there is a strong familial component to PCOS regardless of the diagnostic criteria used to ascertain probands and to assign affected…”
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Diabetes prevalence and risk factors in polycystic ovary syndrome by Legro, R S

“…Polycystic ovary syndrome is a reproductive disorder with a significant impact on fertility. It is secondarily, and perhaps for the individual primarily, a…”
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The relationship between oestrogen and executive functioning in ALS females with emerging Frontotemporal Lobar Degeneration (FTLD) supports a neuroendocrine model of FTLD attenuation by Flaherty, C., Kraft, J., Brothers, A., Harrison, M., Legro, R.S., Manni, A., Yang, C., Simmons, Z.

“…Objective: The prevalence of ALS cognitive or behavioural impairment (ci or bi) consistent with Frontotemporal Degeneration (FTLD) approachs 50%, while ∼5-10%…”
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Prevalence and predictors of dyslipidemia in women with polycystic ovary syndrome by Legro, R S, Kunselman, A R, Dunaif, A

“…Women with polycystic ovary syndrome are hyperandrogenemic and insulin resistant, which are associated with alterations in circulating lipid and lipoprotein…”
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A protocol developing, disseminating and implementing a core outcome set for infertility by Duffy, J M N, Bhattacharya, S, Curtis, C, Evers, J L H, Farquharson, R G, Franik, S, Khalaf, Y, Legro, R S, Lensen, S, Mol, B W, Niederberger, C, Ng, E H Y, Repping, S, Strandell, A, Torrance, H L, Vail, A, van Wely, M, Vuong, N L, Wang, A Y, Wang, R, Wilkinson, J, Youssef, M A, Farquhar, C M

“…We aim to produce, disseminate and implement a core outcome set for future infertility research. Randomized controlled trials (RCTs) evaluating infertility…”
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