Search Results - "LEFORT, A"

Untargeted next-generation sequencing-based first-line diagnosis of infection in immunocompromised adults: a multicentre, blinded, prospective study by Parize, P., Muth, E., Richaud, C., Gratigny, M., Pilmis, B., Lamamy, A., Mainardi, J.-L., Cheval, J., de Visser, L., Jagorel, F., Ben Yahia, L., Bamba, G., Dubois, M., Join-Lambert, O., Leruez-Ville, M., Nassif, X., Lefort, A., Lanternier, F., Suarez, F., Lortholary, O., Lecuit, M., Eloit, M.

“…Infections are the major cause of morbidity and mortality in immunocompromised patients. Improving microbiological diagnosis in these patients is of paramount…”
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A Rapid CRISPR/Cas-based Mutagenesis Assay in Zebrafish for Identification of Genes Involved in Thyroid Morphogenesis and Function by Trubiroha, A., Gillotay, P., Giusti, N., Gacquer, D., Libert, F., Lefort, A., Haerlingen, B., De Deken, X., Opitz, R., Costagliola, S.

“…The foregut endoderm gives rise to several organs including liver, pancreas, lung and thyroid with important roles in human physiology. Understanding which…”
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Pharmacokinetic interaction between rifampicin and clindamycin in staphylococcal osteoarticular infections by Goulenok, T., Seurat, J., Selle, A. de La, Jullien, V., Leflon-Guibout, V., Grall, N., Lescure, F.X., Lepeule, R., Bertrand, J., Fantin, B., Burdet, C., Lefort, A.

“…•A strong pharmacokinetic interaction between clindamycin and rifampicin is observed.•In osteoarticular infection (OAI), rifampicin co-administration…”
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Mortality in Escherichia coli bloodstream infections: antibiotic resistance still does not make it by de Lastours, V, Laouénan, C, Royer, G, Carbonnelle, E, Lepeule, R, Esposito-Farèse, M, Clermont, O, Duval, X, Fantin, B, Mentré, F, Decousser, J W, Denamur, E, Lefort, A

“…Escherichia coli bloodstream infections (BSIs) account for high mortality rates (5%-30%). Determinants of death are unclear, especially since the emergence of…”
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Expression of CTX-M-15 limits the efficacy of ceftolozane/tazobactam against Escherichia coli in a high-inoculum murine peritonitis model by Canovas, J., Petitjean, G., Chau, F., Le Monnier, A., Fantin, B., Lefort, A.

“…Among carbapenem-sparing therapies, ceftolozane/tazobactam has been proposed for the treatment of infections due to CTX-M-15-producing Escherichia coli…”
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Diagnosis, management and outcome of Candida endocarditis by Lefort, A., Chartier, L., Sendid, B., Wolff, M., Mainardi, J.-L., Podglajen, I., Desnos-Ollivier, M., Fontanet, A., Bretagne, S., Lortholary, O.

“…Limited data exist on Candida endocarditis (CE) outcome in the era of new antifungals. As early diagnosis of CE remains difficult, non-culture-based tools need…”
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Observations of periglacial landforms in Utopia Planitia with the High Resolution Imaging Science Experiment (HiRISE) by Lefort, A., Russell, P. S., Thomas, N., McEwen, A. S., Dundas, C. M., Kirk, R. L.

“…The region of western Utopia Planitia (80–105°E, 40–55°N) displays several types of landforms similar to Earth periglacial features, including scallop‐shaped…”
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Activity of temocillin in a lethal murine model of infection of intra-abdominal origin due to KPC-producing Escherichia coli by Alexandre, K, Chau, F, Guérin, F, Massias, L, Lefort, A, Cattoir, V, Fantin, B

“…Temocillin is a 6-α-methoxy derivative of ticarcillin that shows in vitro activity against Enterobacteriaceae producing Klebsiella pneumoniae carbapenemase…”
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Kinetochore KMN network gene CASC5 mutated in primary microcephaly by GENIN, Anne, DESIR, Julie, LIBERT, Frederick, PIRSON, Isabelle, ABRAMOWICZ, Marc, LAMBERT, Nelle, BIERVLIET, Martine, VAN DER AA, Nathalie, PIERQUIN, Genevieve, KILLIAN, Audrey, TOSI, Mario, URBINA, Montse, LEFORT, Anne

“…Several genes expressed at the centrosome or spindle pole have been reported to underlie autosomal recessive primary microcephaly (MCPH), a neurodevelopmental…”
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Fluconazole for the management of invasive candidiasis: where do we stand after 15 years? by Charlier, C., Hart, E., Lefort, A., Ribaud, P., Dromer, F., Denning, D. W., Lortholary, O.

“…Candida spp. are responsible for most of the fungal infections in humans. Available since 1990, fluconazole is well established as a leading drug in the…”
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Efficacy of vancomycin lock therapy for totally implantable venous access port-related infection due to coagulase-negative staphylococci in 100 patients with cancer by Lafaurie, Matthieu, Montlahuc, Claire, Kerneis, Solen, de Lastours, Victoire, Abgrall, Sophie, Manceron, Véronique, Couzigou, Carine, Chabrol, Amélie, de Raigniac, Axelle, Lescure, Xavier, Longuet, Pascale, Lesprit, Philippe, Vanjak, Dominique, Lepeule, Raphael

“…Abstract Objectives Data on the efficacy of vancomycin catheter lock therapy (VLT) for conservative treatment of totally implantable venous access port-related…”
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Body composition and anti-neoplastic treatment in adult and older subjects - A systematic review by Gérard, Stéphane, Bréchemier, D., Lefort, A., Lozano, S., Abellan Van Kan, G., Filleron, T., Mourey, L., Bernard-Marty, C., Rougé-Bugat, M. E., Soler, V., Vellas, B., Cesari, M., Rolland, Y., Balardy, L.

“…Background T he estimation of the risk of poor tolerance and overdose of antineoplastic agents protocols represents a major challenge in oncology, particularly…”
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Bacteraemia caused by third-generation cephalosporin-resistant Escherichia coli in France: prevalence, molecular epidemiology and clinical features by Courpon-Claudinon, A., Lefort, A., Panhard, X., Clermont, O., Dornic, Q., Fantin, B., Mentré, F., Wolff, M., Denamur, E., Branger, C.

“…Escherichia coli is one of the major pathogens responsible for bactaeremia. Empirical antibiotherapy of these infections usually relies on third-generation…”
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Informational resources used by farmers with ruminants and monogastrics for animal health monitoring: importance of sensory indicators by Manoli, C., Di Bianco, S., Sigwalt, A., Defois, J., Dufay-lefort, A.C., Gambara, T., Gabriac, M.S., Leblanc Maridor, M., Duvauchelle Waché, A.

“…•Practices on animal health monitoring have been investigated.•We focused on Informational Resources that farmers use to pilot animal health.•Six types of…”
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Cefotaxime and Amoxicillin-Clavulanate Synergism against Extended-Spectrum-β-Lactamase-Producing Escherichia coli in a Murine Model of Urinary Tract Infection by Rossi, B, Soubirou, J F, Chau, F, Massias, L, Dion, S, Lepeule, R, Fantin, B, Lefort, A

“…We investigated the efficacies of cefotaxime (CTX) and amoxicillin (AMX)-clavulanate (CLA) (AMC) against extended-spectrum-β-lactamase (ESBL)-producing…”
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Scalloped terrains in the Peneus and Amphitrites Paterae region of Mars as observed by HiRISE by Lefort, A., Russell, P.S., Thomas, N.

“…The Peneus and Amphitrites Paterae region of Mars displays large areas of smooth, geologically young terrains overlying a rougher and older topography. These…”
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The intravenous vancomycin prescription practices of French infectious disease specialists: A cross-sectional observational study by Lemaitre, M., Galy, A., de Lastours, V., Thill, P., Tattevin, P., Lefort, A.

“…•Infectious Disease specialists generally prescribe vancomycin by continuous administration, preceded by a loading dose.•Evaluation of co-administrations,…”
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Empirical therapies among adults hospitalized for community-acquired upper urinary tract infections: A decision-tree analysis of mortality, costs, and resistance by Parienti, J.J., MD, PhD, Lucet, J.C., MD, PhD, Lefort, A., MD, PhD, Armand-Lefèvre, L., MD, PhD, Wolff, M., MD, PhD, Caron, F., MD, PhD, Cattoir, V., MD, PhD, Yazdanpanah, Y., MD, PhD

“…Background Poor outcomes occur when patients with serious infections receive antibiotics to which the organisms are resistant. Methods Decision trees simulated…”
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The Emergence of Linezolid Resistance among Enterococci in Intestinal Microbiota of Treated Patients Is Unrelated to Individual Pharmacokinetic Characteristics by BOURGEOIS-NICOLAOS, N, NGUYEN, T. T, ANDREMONT, A, DUVAL, X, DEFRANCE, G, MASSIAS, L, ALAVOINE, L, LEFORT, A, NOEL, V, SENNEVILLE, E, DOUCET-POPULAIRE, F, MENTRE, F

“…Linezolid is an antimicrobial agent for the treatment of multiresistant Gram-positive infections. We assessed the impact of linezolid on the microbiota and the…”
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Diversity of accessory genome of human and livestock-associated ST398 methicillin resistant Staphylococcus aureus strains by Hallin, M., De Mendonça, R., Denis, O., Lefort, A., El Garch, F., Butaye, P., Hermans, K., Struelens, M.J.

“…▶ We explored the accessory and CV genomes of ST398 LA-, HA- and CA-MRSA strains. ▶ We used a DNA-microarray targeting ∼400 resistance, adhesion and virulence…”
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