Search Results - "LEFEBVRE, Philippe"

Hepatic sexual dimorphism — implications for non-alcoholic fatty liver disease by Lefebvre, Philippe, Staels, Bart

“…The liver is often thought of as a single functional unit, but both its structural and functional architecture make it highly multivalent and adaptable. In any…”
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Distinct but complementary contributions of PPAR isotypes to energy homeostasis by Dubois, Vanessa, Eeckhoute, Jérôme, Lefebvre, Philippe, Staels, Bart

“…Peroxisome proliferator-activated receptors (PPARs) regulate energy metabolism and hence are therapeutic targets in metabolic diseases such as type 2 diabetes…”
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Bile Acid Control of Metabolism and Inflammation in Obesity, Type 2 Diabetes, Dyslipidemia, and Nonalcoholic Fatty Liver Disease by Chávez-Talavera, Oscar, Tailleux, Anne, Lefebvre, Philippe, Staels, Bart

“…Bile acids are signaling molecules that coordinately regulate metabolism and inflammation via the nuclear farnesoid X receptor (FXR) and the Takeda G…”
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Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation by Lefebvre, Philippe, Cariou, Bertrand, Lien, Fleur, Kuipers, Folkert, Staels, Bart

“…Institut Pasteur de Lille, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR 545, and Université de Lille 2, Faculté des Sciences…”
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Auditory resting-state network connectivity in tinnitus: a functional MRI study by Maudoux, Audrey, Lefebvre, Philippe, Cabay, Jean-Evrard, Demertzi, Athena, Vanhaudenhuyse, Audrey, Laureys, Steven, Soddu, Andrea

“…The underlying functional neuroanatomy of tinnitus remains poorly understood. Few studies have focused on functional cerebral connectivity changes in tinnitus…”
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Sleep-disordered breathing diagnosis: a comprehensive audit of home sleep testing in real clinical settings by Toorens, Delphine, Tombu, Sophie, Camby, Séverine, Rogister, Florence, Chakar, Bassam, Fanielle, Julien, Bruwier, Annick, Lefebvre, Philippe P., Poirrier, Anne-Lise

“…Purpose This study aimed to investigate the indications and outcomes of Home Sleep Testing (HST) for patients with suspected obstructive sleep apnea (OSA),…”
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General molecular biology and architecture of nuclear receptors by Pawlak, Michal, Lefebvre, Philippe, Staels, Bart

“…Nuclear receptors (NRs) regulate and coordinate multiple processes by integrating internal and external signals, thereby maintaining homeostasis in front of…”
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Hepatic Molecular Signatures Highlight the Sexual Dimorphism of Nonalcoholic Steatohepatitis (NASH) by Vandel, Jimmy, Dubois‐Chevalier, Julie, Gheeraert, Céline, Derudas, Bruno, Raverdy, Violetta, Thuillier, Dorothée, Gaal, Luc, Francque, Sven, Pattou, François, Staels, Bart, Eeckhoute, Jérôme, Lefebvre, Philippe

“…Background and Aims Nonalcoholic steatohepatitis (NASH) is considered as a pivotal stage in nonalcoholic fatty liver disease (NAFLD) progression, given that it…”
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Factors Predictive of Binaural Hearing Restoration by Cochlear Implant in Single-Sided Deafness by Gersdorff, Guillaume, Péan, Vincent, Camby, Séverine, Barriat, Sébastien, Lefebvre, Philippe P

“…Cochlear implants (CIs) can restore binaural hearing in cases of single-sided deafness (SSD). However, studies with a high level of evidence in support of this…”
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Mitochondrial Dysfunction as an Arrhythmogenic Substrate by Montaigne, David, MD, PhD, Marechal, Xavier, PhD, Lefebvre, Philippe, PhD, Modine, Thomas, MD, PhD, Fayad, Georges, MD, Dehondt, Helene, Eng, Hurt, Christopher, MD, Coisne, Augustin, MD, Koussa, Mohamed, MD, Remy-Jouet, Isabelle, PhD, Zerimech, Farid, MD, Boulanger, Eric, MD, PhD, Lacroix, Dominique, MD, PhD, Staels, Bart, PhD, Neviere, Remi, MD, PhD

“…Objectives This study sought to provide bedside evidence of the potential link between cardiac mitochondrial dysfunction and arrhythmia as reported in bench…”
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Cochlear Implant: Analysis of the Frequency-to-Place Mismatch with the Table-Based Software OTOPLAN® and Its Influence on Hearing Performance by Dessard, Laura, Gersdorff, Guillaume, Ivanovik, Nicola, Zoca-Assadi, Masoud, Nopp, Peter, Camby, Séverine, Lefebvre, Philippe P

“…The purpose of this study was to compare the originally applied frequency allocation of cochlear implant electrodes assigned by default at the time of…”
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The transrepressive activity of peroxisome proliferator‐activated receptor alpha is necessary and sufficient to prevent liver fibrosis in mice by Pawlak, Michal, Baugé, Eric, Bourguet, William, Bosscher, Karolien, Lalloyer, Fanny, Tailleux, Anne, Lebherz, Corinna, Lefebvre, Philippe, Staels, Bart

“…Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent and strongly associated with central obesity, dyslipidemia, and insulin resistance…”
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Impact of local anesthesia on ciliary dyskinesia diagnosis by digital high-speed videomicroscopy by Benchimol, Lionel, Bricmont, Noemie, Bonhiver, Romane, Hans, Grégory A, Lefebvre, Philippe, Kempeneers, Celine, Poirrier, Anne-Lise

“…This prospective study investigates the impact of local anesthesia on ciliary function in nasal epithelium. The primary objective was to assess whether…”
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Role for the metalloproteinase ADAM28 in the control of airway inflammation, remodelling and responsiveness in asthma by Bendavid, Guillaume, Hubeau, Céline, Perin, Fabienne, Gillard, Alison, Nokin, Marie-Julie, Carnet, Oriane, Gerard, Catherine, Noel, Agnès, Lefebvre, Philippe, Rocks, Natacha, Cataldo, Didier

“…Asthma is characterized by morphological modifications of the airways (inflammation and remodelling) and bronchial hyperresponsiveness. Mechanisms linking…”
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Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects by Borgs, Laurence, Peyre, Elise, Alix, Philippe, Hanon, Kevin, Grobarczyk, Benjamin, Godin, Juliette D., Purnelle, Audrey, Krusy, Nathalie, Maquet, Pierre, Lefebvre, Philippe, Seutin, Vincent, Malgrange, Brigitte, Nguyen, Laurent

“…Some mutations of the LRRK2 gene underlie autosomal dominant form of Parkinson’s disease (PD). The G2019S is a common mutation that accounts for about 2% of PD…”
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Farnesoid X Receptor Inhibits the Transcriptional Activity of Carbohydrate Response Element Binding Protein in Human Hepatocytes by Caron, Sandrine, Huaman Samanez, Carolina, Dehondt, Hélène, Ploton, Maheul, Briand, Olivier, Lien, Fleur, Dorchies, Emilie, Dumont, Julie, Postic, Catherine, Cariou, Bertrand, Lefebvre, Philippe, Staels, Bart

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A Retrospective Multicentre Cohort Review of Patient Characteristics and Surgical Aspects versus the Long-Term Outcomes for Recipients of a Fully Implantable Active Middle Ear Implant by Lefebvre, Philippe P, Gisbert, Javier, Cuda, Domenico, Tringali, Stéphane, Deveze, Arnaud

“…To summarise treatment outcomes compared to surgical and patient variables for a multicentre recipient cohort using a fully implantable active middle ear…”
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The nuclear bile acid receptor FXR is a PKA- and FOXA2-sensitive activator of fasting hepatic gluconeogenesis by Ploton, Maheul, Mazuy, Claire, Gheeraert, Céline, Dubois, Vanessa, Berthier, Alexandre, Dubois-Chevalier, Julie, Maréchal, Xavier, Bantubungi, Kadiombo, Diemer, Hélène, Cianférani, Sarah, Strub, Jean-Marc, Helleboid-Chapman, Audrey, Eeckhoute, Jérôme, Staels, Bart, Lefebvre, Philippe

“…[Display omitted] •FXR synergizes with the glucagon signaling pathway to regulate hepatic gluconeogenesis in vivo and in vitro.•FXR positively regulates…”
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Decreased circulating IPA levels identify subjects with metabolic comorbidities: A multi-omics study by Ballanti, Marta, Antonetti, Lorenzo, Mavilio, Maria, Casagrande, Viviana, Moscatelli, Alessandro, Pietrucci, Daniele, Teofani, Adelaide, Internò, Chiara, Cardellini, Marina, Paoluzi, Omero, Monteleone, Giovanni, Lefebvre, Philippe, Staels, Bart, Mingrone, Geltrude, Menghini, Rossella, Federici, Massimo

“…In recent years several experimental observations demonstrated that the gut microbiome plays a role in regulating positively or negatively metabolic…”
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Glial but not neuronal development in the cochleo-vestibular ganglion requires Sox10 by Breuskin, Ingrid, Bodson, Morgan, Thelen, Nicolas, Thiry, Marc, Borgs, Laurence, Nguyen, Laurent, Stolt, Claus, Wegner, Michael, Lefebvre, Philippe P, Malgrange, Brigitte

“…J. Neurochem. (2010) 114, 1827-1839. The cochleo-vestibular ganglion contains neural crest-derived glial cells and sensory neurons that are derived from the…”
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