Search Results - "LEFEBVRE, Patricia"
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Prevalence, Molecular Epidemiology, and Clinical Significance of Heterogeneous Glycopeptide-Intermediate Staphylococcus aureus in Liver Transplant Recipients
Published in Journal of Clinical Microbiology (01-11-2003)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Phase I Pharmacokinetic, Food Effect, and Pharmacogenetic Study of Oral Irinotecan Given as Semisolid Matrix Capsules in Patients with Solid Tumors
Published in Clinical cancer research (15-02-2005)“…Purpose: To characterize the maximum-tolerated dose, recommended dose, dose-limiting toxicities (DLT), pharmacokinetic profile, and food effect of orally…”
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3
Single- and Multiple-Dose Pharmacokinetics of Riluzole in White Subjects
Published in Journal of clinical pharmacology (01-09-1997)“…Riluzole is a novel neuroprotective agent that has been developed for the treatment of amyotrophic lateral sclerosis. A series of studies was undertaken to…”
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4
Accuracy and generalizability of using automated methods for identifying adverse events from electronic health record data: a validation study protocol
Published in BMC health services research (16-02-2017)“…Adverse events (AEs) in acute care hospitals are frequent and associated with significant morbidity, mortality, and costs. Measuring AEs is necessary for…”
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5
Phase I study of an oral formulation of irinotecan administered daily for 14 days every 3 weeks in patients with advanced solid tumours
Published in Cancer chemotherapy and pharmacology (01-03-2005)“…A phase I study was conducted with oral irinotecan given daily for 14 days every 3 weeks in 45 patients with solid tumours to establish the maximum tolerated…”
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6
Phase I and pharmacokinetic study of two sequences of gemcitabine and docetaxel administered weekly to patients with advanced cancer
Published in Cancer chemotherapy and pharmacology (01-08-2001)“…To determine the maximum tolerated dose (MTD), dose-limiting toxicity (DLT), and effect of drug sequence on toxicities and pharmacokinetics of the combination…”
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7
Enhancement of O6-methylguanine-DNA-methyltransferase activity induced by various treatments in mammalian cells
Published in Cancer research (Chicago, Ill.) (01-11-1986)“…The O6-methylguanine-DNA-methyltransferase (methyltransferase) activity was determined in a rat hepatoma cell line after treatment with ultraviolet or…”
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A human cell line proficient in O6-methylguanine-DNA-methyltransferase and hypersensitive to alkylating agents
Published in Carcinogenesis (New York) (01-08-1993)“…The involvement of O6-methylguanine (O6-meGua) in mutagenesis is well established, while the toxic effect of these residues is still controversial. In this…”
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Hospitals report on medication safety in Canada
Published in Dynamics (Pembroke) (22-09-2010)“…Measurement of safety can be difficult. Given that incident reporting systems rely primarily on voluntary reporting and some types of medication incidents may…”
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10
Potentiation of N-methyl-N'-nitro-N-nitrosoguanidine-induced O6-methylguanine-DNA-methyltransferase activity in a rat hepatoma cell line by poly (ADP-ribose) synthesis inhibitors
Published in Biochemical and biophysical research communications (30-08-1989)“…The O6-methylguanine-DNA-methyltransferase (transferase) activity in a rat hepatoma cell line (H4 cells) is enhanced as a response to DNA damaging agents. To…”
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Journal Article -
11
On-chip microfluidics for proteomic analysis by electrospray ionization/mass spectrometry
Published in 1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) (2000)“…Describes the development of a silicon integrated demonstrator coupled to an ElectroSpray Ionization source in view of protein analysis by Mass Spectrometry…”
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Conference Proceeding