Search Results - "LEE, Tina X"

Phosphatidylinositol 3-Kinase/AKT Pathway Activation in Human Vestibular Schwannoma by Jacob, Abraham, Lee, Tina X., Neff, Brian A., Miller, Shyra, Welling, Bradley D., Chang, Long-Sheng

“…The neurofibromatosis 2 gene, which encodes the tumor suppressor protein merlin, is frequently mutated in vestibular schwannomas (VS). Merlin can inhibit…”
Get full text

Growth inhibitory and anti-tumour activities of OSU-03012, a novel PDK-1 inhibitor, on vestibular schwannoma and malignant schwannoma cells by Lee, Tina X, Packer, Mark D, Huang, Jie, Akhmametyeva, Elena M, Kulp, Samuel K, Chen, Ching-Shih, Giovannini, Marco, Jacob, Abraham, Welling, D. Bradley, Chang, Long-Sheng

“…Abstract Background Vestibular schwannomas (VS) frequently express high levels of activated AKT. Small-molecule inhibitors of AKT signalling may have…”
Get full text

Growth inhibitory and anti-tumour activities of OSU-03012, a novel PDK-1 inhibitor, on vestibular schwannoma and malignant schwannoma cells by LEE, Tina X, PACKER, Mark D, JIE HUANG, AKHMAMETYEVA, Elena M, KULP, Samuel K, CHEN, Ching-Shih, GIOVANNINI, Marco, JACOB, Abraham, BRADLEY WELLING, D, CHANG, Long-Sheng

Get full text

Analysis of Transcripts Derived from Sequences Upstream of the Bidirectional Mouse Thymidylate Synthase Promoter by Lee, Tina X., Johnson, Lee F.

“…The promoter of the mouse thymidylate synthase (TS) gene lacks a TATAA box and an initiator element and is capable of directing transcriptional initiation with…”
Get full text

Pre-mRNA processing enhancer (PPE) element increases the expression of an intronless thymidylate synthase gene but does not affect intron-dependent S phase regulation by Lee, Tina X., Johnson, Lee F.

“…The pre‐mRNA processing enhancer (PPE) element is an RNA sequence element derived from the intronless HSV‐TK gene. Insertion of the element into the highly…”
Get full text