Search Results - "LEE, Mase"

Comparative Metabolite Profiling of Wild and Cultivated Justicia procumbens L. Based on 1H-NMR Spectroscopy and HPLC-DAD Analysis by Lee, Hyunyong, Jeon, Jihyun, Yoon, Joobyoung, Kim, Seung-Hwan, Choi, Hyun Sik, Kang, Jong Seung, Lee, Yong Sup, Lee, Mase, Kim, Young Ho, Chang, Hwan Bong

“…Justicia procumbens L. is known across Korea, India, China, and Taiwan as a remedy against fever, cough, sore throat, and cirrhosis of ascites. J. procumbens…”
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The medicinal chemistry of 5-HT6 receptor ligands with a focus on arylsulfonyltryptamine analogs by Glennon, Richard A, Siripurapu, Uma, Roth, Bryan L, Kolanos, Renata, Bondarev, Mikhail L, Sikazwe, Donald, Lee, Mase, Dukat, Małgorzata

“…Arylsulfonyl analogs of aminopyrimidines (e.g. Ro 04-6790; 2), aminopyridines (e.g. Ro 63-0563; 3), 1-phenylpiperazines (e.g. SB-271046; 4), and tryptamines…”
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Preparation of Novel Donepezil Long‐Acting Injectable, IVL3003, and its Pharmacokinetic Study via Subcutaneous Injection in Dogs and Monkeys by Lee, Mase, Lee, Sangno

“…Background Donepezil is a selective oral acetylcholinesterase inhibitor to treat Alzheimer’s disease (AD). Most patients with AD need help with taking oral…”
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In Vitro Inhibitory Effect of Some Flavonoids on Rotavirus Infectivity by BAE, Eun-Ah, HAN, Myung Joo, LEE, Mase, KIM, Dong-Hyun

“…The inhibitory effects of some flavonoids on the infectivity of rotavirus, which predominantly causes sporadic diarrhea in infants and young children, were…”
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Development of a novel long-acting injectable, IVL4002 for modulation of multiple sclerosis: Pharmacokinetics and efficacy studies in an experimental autoimmune encephalomyelitis mouse model by Kim, Ju Hee, Youm, Soyoung, Lee, Slgirim, Lee, Mase

“…Multiple sclerosis (MS), a prevalent autoimmune disease and lacking a well-defined etiology and cures, drove the development of diverse disease-modifying…”
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A Phase I, Open-Label, Sequential, Single-Dose Clinical Trial to Evaluate the Pharmacokinetic, Pharmacodynamic, and Safety of IVL3001, a Finasteride-Based Novel Long-Acting Injection for Androgenetic Alopecia by Kim, Heesun, Ryu, Choongho, Lee, Mase, Lee, Kyeong-Ryoon, Kim, Juhee

“…Introduction Hair loss is driven by multiple factors, including genetics. Androgenetic alopecia (AGA) is a condition in which treatments necessitate prolonged…”
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Construction of three types of fused isoindoles via furan-pyrrole ring exchange reaction by Lee, Mase, Moritomo, Hiroyuki, Kanematsu, Ken

“…The new synthetic route of three types of fused isoindoles using furan-pyrrole ring exchange reaction as the main synthetic strategy is presented…”
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Formulation and evaluation of an alternative triglyceride-free propofol microemulsion by Cho, Jaepyoung, Cho, Jin Cheol, Lee, Pungsok, Lee, Mase, Oh, Euichaul

“…A new triglyceride-free propofol microemulsion for intravenous injection was formulated using nonionic surfactants, poloxamers and polyethylene glycol 660…”
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2-Substituted tryptamines: agents with selectivity for 5-HT(6) serotonin receptors by Glennon, R A, Lee, M, Rangisetty, J B, Dukat, M, Roth, B L, Savage, J E, McBride, A, Rauser, L, Hufeisen, S, Lee, D K

“…Several 2-alkyl-5-methoxytryptamine analogues were designed and prepared as potential 5-HT(6) serotonin agonists. It was found that 5-HT(6) receptors…”
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N1-(Benzenesulfonyl)tryptamines as novel 5-HT6 antagonists by YUCHING TSAI, DUKAT, Malgorzata, SLASSI, Abdelmalik, MACLEAN, Neil, DEMCHYSHYN, Lidia, SAVAGE, Jason E, ROTH, Bryan L, HUFESEIN, Sandy, LEE, Mase, GLENNON, Richard A

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2-Substituted Tryptamines:  Agents with Selectivity for 5-HT6 Serotonin Receptors by Glennon, Richard A, Lee, Mase, Rangisetty, Jagadeesh B, Dukat, Malgorzata, Roth, Bryan L, Savage, Jason E, McBride, Ace, Rauser, Laura, Hufeisen, Sandy, Lee, David K. H

“…Several 2-alkyl-5-methoxytryptamine analogues were designed and prepared as potential 5-HT6 serotonin agonists. It was found that 5-HT6 receptors accommodate…”
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N1-(Benzenesulfonyl)tryptamines as novel 5-HT6 antagonists by Tsai, Y, Dukat, M, Slassi, A, MacLean, N, Demchyshyn, L, Savage, J E, Roth, B L, Hufesein, S, Lee, M, Glennon, R A

“…N-Benzenesulfonyl-5-methoxy-N,N-dimethyltryptamine (BS/5-OMe DMT; 5) was shown to bind at human 5-HT6 serotonin receptors with high affinity (Ki = 2.3 nM)…”
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1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands by LEE, Mase, RANGISETTY, Jagadeesh B, PULLAGURLA, Manik R, DUKAT, Małgorzata, SETOLA, Vince, ROTH, Bryan L, GLENNON, Richard A

“…4-Sulfonyl analogs of 1-(1-naphthyl)piperazine bind at human 5-HT6 receptors and represent a novel class of human 5-HT6 receptor ligands…”
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S(+)- and R(−) N-Methyl-1-(3,4-methylenedioxyphenyl)-2-aminopropane (MDMA) as discriminative stimuli: Effect of cocaine by Bondareva, Tatiana, Wesołowska, Anna, Dukat, Małgorzata, Lee, Mase, Young, Richard, Glennon, Richard A.

“…Racemic N-methyl-1-(3,4-methylenedioxyphenyl)-2-aminopropane (methylenedioxymethamphetamine, MDMA), a central stimulant and empathogenic agent, and cocaine are…”
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1-(1-Naphthyl)piperazine as a novel template for 5-HT 6 serotonin receptor ligands by Lee, Mase, Rangisetty, Jagadeesh B., Pullagurla, Manik R., Dukat, Małgorzata, Setola, Vince, Roth, Bryan L., Glennon, Richard A.

“…4-Arylsulfone derivatives of 1-(1-naphthyl)piperazine represent a novel class of human 5-HT 6 serotonin receptor ligands. In particular, compounds such as 1f (…”
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3-(4-Aminobutyn-1-yl)pyridines: binding at α4β2 nicotinic cholinergic receptors by Dogruer, Deniz, Lee, Mase, Dukat, Malgorzata, Damaj, M.Imad, Martin, Billy R., Glennon, Richard A.

“…The binding of a series pyridylbutynylamines 6 was examined at α4β2 nACh receptors. Structural modifications, comparing 6 with pyridyl ethers 2, did not…”
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Quaternary ammonium 3-(aminoethoxy)pyridines as antinociceptive agents by Simsek, Rahime, Chang-Fong, Jean, Lee, Mase, Dukat, Malgorzata, Imad Damaj, M., Martin, Billy R., Glennon, Richard A.

“…Quaternization via N-methylation of the terminal amines of a series of 3-(dialkylaminoethoxy)pyridines resulted in analogues that displayed up to 50–60-fold…”
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Enantioselective Total Synthesis of cis-Trikentrin B by Lee, Mase, Ikeda, Izumi, Kawabe, Tsuyoshi, Mori, Sayaka, Kanematsu, Ken

“…Natural cis-trikentrin B was synthesized enantioselectively using, as key steps, an intramolecular Diels−Alder reaction of an allenic dienamide followed by…”
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6-(2-Phenylethyl)nicotine: A novel nicotinic cholinergic receptor ligand by Ramunno, Anna, Dukat, Małgorzata, Lee, Mase, Young, Richard, El-Zahabi, Mohamed, Damaj, M. Imad, Martin, Billy, Glennon, Richard A.

“…Defying presumed structure–affinity relationships, nicotine analog 1b ( K i = 15 nM) was unexpectedly found to bind to α4β2 nACh receptors. Administered via an…”
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3-(4-Aminobutyn-1-yl)pyridines: binding at alpha 4 beta 2 nicotinic cholinergic receptors by Dogruer, Deniz, Lee, Mase, Dukat, Malgorzata, Damaj, M Imad, Martin, Billy R, Glennon, Richard A

“…The binding of a series pyridylbutynylamines 6 was examined at alpha4beta2 nACh receptors. Structural modifications, comparing 6 with pyridyl ethers 2, did not…”
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